Description
Book Synopsisa gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide
Mark Leake, University of York
destined to become a standard reference. Not just a how to' handbook but also an accessible primer in the essentials of kinetic theory and practice.
Michael Geeves, University of Kent
covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques
Stephen Halford, University of Bristol
This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as
Trade Review
"a unique and innovative contribution to the field... the first to my knowledge that covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques… a significant contribution."
—Prof. Stephen Halford, University of Bristol
" Enzyme kinetics is regaining its rightful place at the center of molecular and cellular biology…. Thus, a new generation of students will benefit from Clive Bagshaw's Biomolecular Kinetics: A Step-By-Step Guide"
—Jonathon Howard, Eugene Higgins Professor of Molecular Biophysics & Biochemistry, Yale
"Comprehensive and well written."
—Enrico Di Cera, MD, Alice A. Doisy Professor and Chairman, Department of Biochemistry and Molecular Biology, Saint Louis University
"This book is destined to become a standard reference on the bookshelf of any laboratory with an interest in kinetic approaches to biology. Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory & practice."
—Prof. Michael Geeves, University of Kent
"This book is a much needed modern update for the underserved field of biomolecular kinetics. It covers the practical ‘how to’ and troubleshooting information for experiments together with the fundamentals in one place. It is written by a genuine expert in kinetic techniques, and is beautifully illustrated. It is highly accessible to readers at all levels, and I highly recommend this text to anyone wishing to learn more about the power and potential applications of kinetics techniques."
—Prof. Emma Raven, University of Leicester
"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide through the nuances of biomolecular kinetics, penned by one of the giants of this complex but fundamental field of the life sciences"
—Prof. Mark Leake, University of York
"This well written, concise but very comprehensive text will be the go-to book for those wanting to take advantage of new (and classic) approaches, and the challenges and the opportunities they provide."
—Bob Callender, Professor of Biochemistry, Albert Einstein College of Medicine
"This is a comprehensive and detailed yet clear and much needed book. Kinetic methods are applied throughout biological sciences and for everyone who is using them this is a must-read."
—Per Jemth, Department of Medical Biochemistry and Microbiology, Uppsala University
"Finally, a book that supports a practical entry into kinetics for enzymologists and other biochemists. The field sorely needs a solid, accessible kinetics text like this…."
—Bruce A. Palfey, Department of Biological Chemistry, University of Michigan Medical School
"a lively book with a splendid balance between the description of most recent experimental work and easily comprehensible theoretical interpretations…. [It] should help to encourage students to enter this exciting field and help research workers to expand the range of their endeavours."
—Herbert Gutfreund, University of Bristol
"a unique and innovative contribution to the field... the first to my knowledge that covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques… a significant contribution."
—Prof. Stephen Halford, University of Bristol
" Enzyme kinetics is regaining its rightful place at the center of molecular and cellular biology…. Thus, a new generation of students will benefit from Clive Bagshaw's Biomolecular Kinetics: A Step-By-Step Guide"
—Jonathon Howard, Eugene Higgins Professor of Molecular Biophysics & Biochemistry, Yale
"Comprehensive and well written."
—Enrico Di Cera, MD, Alice A. Doisy Professor and Chairman, Department of Biochemistry and Molecular Biology, Saint Louis University
"This book is destined to become a standard reference on the bookshelf of any laboratory with an interest in kinetic approaches to biology. Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory & practice."
—Prof. Michael Geeves, University of Kent
"This book is a much needed modern update for the underserved field of biomolecular kinetics. It covers the practical ‘how to’ and troubleshooting information for experiments together with the fundamentals in one place. It is written by a genuine expert in kinetic techniques, and is beautifully illustrated. It is highly accessible to readers at all levels, and I highly recommend this text to anyone wishing to learn more about the power and potential applications of kinetics techniques."
—Prof. Emma Raven, University of Leicester
"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide through the nuances of biomolecular kinetics, penned by one of the giants of this complex but fundamental field of the life sciences"
—Prof. Mark Leake, University of York
"This well written, concise but very comprehensive text will be the go-to book for those wanting to take advantage of new (and classic) approaches, and the challenges and the opportunities they provide."
—Bob Callender, Professor of Biochemistry, Albert Einstein College of Medicine
"This is a comprehensive and detailed yet clear and much needed book. Kinetic methods are applied throughout biological sciences and for everyone who is using them this is a must-read."
—Per Jemth, Department of Medical Biochemistry and Microbiology, Uppsala University
"Finally, a book that supports a practical entry into kinetics for enzymologists and other biochemists. The field sorely needs a solid, accessible kinetics text like this…."
—Bruce A. Palfey, Department of Biological Chemistry, University of Michigan Medical School
"a lively book with a splendid balance between the description of most recent experimental work and easily comprehensible theoretical interpretations…. [It] should help to encourage students to enter this exciting field and help research workers to expand the range of their endeavours."
—Herbert Gutfreund, University of Bristol
Table of ContentsIntroduction. Kinetic Theory. Some Underlying Physical Principles. Enzyme Kinetics. Beyond Enzyme Kinetics. Experimental Strategies. Instrumentation. Data Analysis. Single-Molecule Kinetics. Kinetic Thinking: Back To The Future. Appendices
