Description
Book SynopsisThe bestselling introduction to bioinformatics and genomics now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline.
Table of ContentsPart I Analyzing DNA, RNA, and Protein Sequences
1 Introduction 3
2 Access to Sequence Data and Related Information 19
3 Pairwise Sequence Alignment 69
4 Basic Local Alignment Search Tool (BLAST) 121
5 Advanced Database Searching 167
6 Multiple Sequence Alignment 205
7 Molecular Phylogeny and Evolution 245
Part II Genomewide Analysis of DNA, RNA, and Protein
8 DNA: The Eukaryotic Chromosome 307
9 Analysis of Next-Generation Sequence Data 377
10 Bioinformatic Approaches to Ribonucleic Acid (RNA) 433
11 Gene Expression: Microarray and RNA-seq Data Analysis 479
12 Protein Analysis and Proteomics 539
13 Protein Structure 589
14 Functional Genomics 635
Part III Genome Analysis
15 Genomes Across the Tree of Life 699
16 Completed Genomes: Viruses 755
17 Completed Genomes: Bacteria and Archaea 797
18 Eukaryotic Genomes: Fungi 847
19 Eukaryotic Genomes: From Parasites to Primates 887
20 Human Genome 957
21 Human Disease 1011
Glossary 1075
Self-Test Quiz: Solutions 1103
Author Index 1105
Subject Index 1109
