Description
Book SynopsisTable of ContentsForeword vii
Preface ix
Contributors xi
About the Companion Website xvii
1 Biological Sequence Databases 1
Andreas D. Baxevanis
2 Information Retrieval from Biological Databases 19
Andreas D. Baxevanis
3 Assessing Pairwise Sequence Similarity: BLAST and FASTA 45
Andreas D. Baxevanis
4 Genome Browsers 79
Tyra G. Wolfsberg
5 Genome Annotation 117
David S. Wishart
6 Predictive Methods Using RNA Sequences 155
Michael F. Sloma, Michael Zuker, and David H. Mathews
7 Predictive Methods Using Protein Sequences 185
Jonas Reeb, Tatyana Goldberg, Yanay Ofran, and Burkhard Rost
8 Multiple Sequence Alignments 227
Fabian Sievers, Geoffrey J. Barton, and Desmond G. Higgins
9 Molecular Evolution and Phylogenetic Analysis 251
Emma J. Griffiths and Fiona S.L. Brinkman
10 Expression Analysis 279
Marieke L. Kuijjer, Joseph N. Paulson, and John Quackenbush
11 Proteomics and Protein Identification by Mass Spectrometry 315
Sadhna Phanse and Andrew Emili
12 Protein Structure Prediction and Analysis 363
David S. Wishart
13 Biological Networks and Pathways 399
Gary D. Bader
14 Metabolomics 437
David S. Wishart
15 Population Genetics 481
Lynn B. Jorde and W. Scott Watkins
16 Metagenomics and Microbial Community Analysis 505
Robert G. Beiko
17 Translational Bioinformatics 537
Sean D. Mooney and Stephen J. Mooney
18 Statistical Methods for Biologists 555
Hunter N.B. Moseley
Appendices 583
Glossary 591
Index 609
