Description
Book SynopsisThis book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is essential in allowing all those involved to fully profit from these exciting advances. In this comprehensive, up-to-date book, authors from different laboratory and clinical areas link laboratory and clinical topics. Analytical problems such as interferences, false-negative and false-positive results are discussed in depth, and flow-charts offer insights into identifying and avoiding them. Illustrated clinical cases detail the clinical role and limitations of different tumor markers. Lastly, it explores health technology assessment and economic issues.
This is a valuable resource for endocrinologists, oncologists, nuclear medicine physicians, scientists and technologists who want to keep abreast of the latest developments.
Table of ContentsCirculating biomarkers: biological basis, methods and interpretation criteria.- Thyroid tumors: pathology and molecular patholog .- Differentiated thyroid cancer.- Diagnosis, therapy and follow-up.- Thyroglobulin and Thyroglobulin Autoantibodies.- Circulating molecular markers: an overview .- Medullary Thyroid Carcinoma.- Diagnosis, therapy and follow-up.- Calcitonin and Carcinoembryonic Antige .- Procalcitonin: are we ready for clinical use?.- Aggressive and Rare Thyroid Carcinoma:.Diagnosis and clinical management.- Circulating mucines and cytokeratins in aggressive thyroid cancers.- Neuroendocrine tumors: pathology and molecular pathology.- Neuroendocrine tumors: diagnosis, therapy and follow-up.- Chromogranin-A and other neuroendocrine tumour markers.- Neuroendocrine gene transcripts.
