Description
Book SynopsisThis atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI). The purpose for this publication is to fill the gap between the growing clinical relevance and utilization of immunotherapy in medical oncology, mainly based on checkpoint inhibitors, and the need for experienced imagers with reliable tools assessing response to treatment. A series of disease-oriented chapters will present the imaging findings during immunotherapy in the major oncological settings, with helpful comparison of functional (PET/CT) and morphological (CT/MRI) patterns of response in individual cases. To complete the atlas, a dedicated chapter will focus on major pitfalls and immune-related adverse events (irAEs) affecting image interpretation during the course of immunotherapy. The concluding chapter will lastly examine the available data and potential developments of immuno-PET, which is considered as the novel frontier of research in this oncological scenario. The atlas will be of high value for radiologists and nuclear medicine specialists at all levels of experience.
Trade Review“This publication is one of the first publications in the field ... . In relation to the innovative content, presented and explained by great experts, this atlas is recommended for diagnostic imagers, who already work with hybrid machines, for students of radiology and nuclear medicine, and for all those interested in immunotherapy. This atlas helps in the correct use of innovative therapies in an oncological reality which is already widely used, although not always appropriately.” (Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 48, 2021)
Table of ContentsPART I BRIEF INTRODUCTION:
1.Immunotherapy in oncology
2.Evolution of response criteria
Part II DIESEASE-ORIENTED APPLICATIONS:
3.CNS
4.Thorax
5.Melanoma
6.Gastrointestinal
7.Genitourinary
8.Hematologic
9.Other tumor types
PART III PITFALLS AND IMMUNE-RELATED ADVERSE EVENTS (IrAEs)
PART IV IMMUNO-PET
