Description

Book Synopsis
This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists.

Table of Contents

Contents

List of Contributors

Part I: Immunohistology of Epithelial Tumors

1 Immunohistology and Molecular Studies of Epithelial Tumors

Heather M. Froehlich and Jose A. Plaza


Part II: Adnexal Neoplasms

2 Immunohistology and Molecular Studies of Sweat Gland Tumors

Ana M. Molina-Ruiz, Laura Fuertes, and Luis Requena

3 Immunohistology and Molecular Studies of Follicular Tumors

Olayemi Sokumbi and Jose A. Plaza

4 Use of Immunohistochemical and Molecular Studies in the Evaluation of the Sebaceous Neoplasms

Doina Ivan, Victor G. Prieto, and Phyu P. Aung

Part III: Immunohistology of Cutaneous Metastases and Its Simulators


5 Cutaneous Metastasis

Danielle M. Wehle, Sadia Salim, and Martin A. Sangueza

Part IV: Immunohistology of Mesenchymal Neoplasms


6 Immunohistology and Molecular Studies of Fibrohistiocytic and Myofibroblastic Cutaneous Tumors

Danny Ghazarian, Sebastien Labonte, Brendan Craig Dickson, and Ayman Al Habeeb

7 Immunohistology and Molecular Studies of Smooth Muscle and Neural Cutaneous Tumors

Tammie Ferringer

8 New Insights in Vascular Lesions Development and Identification with Immunohistochemical Markers

Omar P. Sangüeza and Julio A. Diaz-Perez

Part V: Immunohistology of Cutaneous Lymphoma


9 Immunohistology and Molecular Studies of Cutaneous B-cell Lymphomas

Juan F. García

10 Immunohistology and Molecular Studies of Cutaneous T-cell Lymphomas and Mimics

Carlos A. Torres-Cabala, Phyu P. Aung, Roberto N. Miranda, and Jonathan L. Curry

11 Immunohistology of Leukemia Cutis and Histiocytic Tumors

Maria Teresa Fernández Figueras, Gustavo Tapia, José Luis Mate, Aurelio Ariza

Part VI: Immunohistology of Melanocytic Lesions

12 Immunohistology of Melanocytic Lesions

Jonathan L. Curry, Michael T. Tetzlaff, Priyadharsini Nagarajan, and Carlos A. Torres-Cabala

Part VII: Molecular Studies of Melanocytic Lesions

13 Molecular Studies of Melanocytic Lesions

Rami Al-Rohil, Priyadharsini Nagarajan, and Michael T. Tetzlaff

Part VIII: Immunohistology of Sentinel Lymph Node in Melanoma

14 Sentinel Lymph Node in Melanoma

Victor G. Prieto

Applied Immunohistochemistry in the Evaluation of

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    A Hardback by Jose A. Plaza, Victor G. Prieto

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      Publisher: Springer International Publishing AG
      Publication Date: Publication Date: 22/08/2016
      ISBN13: 9783319305882, 978-3319305882
      ISBN10: 3319305883

      Description

      Book Synopsis
      This book provides a comprehensive, state-of-the-art account of the role of immunohistochemistry in the diagnosis of skin tumors, which is crucial given that overlapping histologic features and unusual morphologic changes can lead to considerable diagnostic uncertainty. The book reviews in detail the sensitivity and specificity of commonly available antibodies and their pattern of immunostaining. readers will learn when to order antibodies and how to interpret findings. In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. The text is complemented by a wealth of superb images. Helpful histograms and algorithms are included, and clear guidance is provided on the application and interpretation of less commonly used antibodies and immunostains. Applied Immunohistochemistry in the Evaluation of Skin Neoplasms will serve as an extremely valuable resource for practicing dermatopathologists and pathologists.

      Table of Contents

      Contents

      List of Contributors

      Part I: Immunohistology of Epithelial Tumors

      1 Immunohistology and Molecular Studies of Epithelial Tumors

      Heather M. Froehlich and Jose A. Plaza


      Part II: Adnexal Neoplasms

      2 Immunohistology and Molecular Studies of Sweat Gland Tumors

      Ana M. Molina-Ruiz, Laura Fuertes, and Luis Requena

      3 Immunohistology and Molecular Studies of Follicular Tumors

      Olayemi Sokumbi and Jose A. Plaza

      4 Use of Immunohistochemical and Molecular Studies in the Evaluation of the Sebaceous Neoplasms

      Doina Ivan, Victor G. Prieto, and Phyu P. Aung

      Part III: Immunohistology of Cutaneous Metastases and Its Simulators


      5 Cutaneous Metastasis

      Danielle M. Wehle, Sadia Salim, and Martin A. Sangueza

      Part IV: Immunohistology of Mesenchymal Neoplasms


      6 Immunohistology and Molecular Studies of Fibrohistiocytic and Myofibroblastic Cutaneous Tumors

      Danny Ghazarian, Sebastien Labonte, Brendan Craig Dickson, and Ayman Al Habeeb

      7 Immunohistology and Molecular Studies of Smooth Muscle and Neural Cutaneous Tumors

      Tammie Ferringer

      8 New Insights in Vascular Lesions Development and Identification with Immunohistochemical Markers

      Omar P. Sangüeza and Julio A. Diaz-Perez

      Part V: Immunohistology of Cutaneous Lymphoma


      9 Immunohistology and Molecular Studies of Cutaneous B-cell Lymphomas

      Juan F. García

      10 Immunohistology and Molecular Studies of Cutaneous T-cell Lymphomas and Mimics

      Carlos A. Torres-Cabala, Phyu P. Aung, Roberto N. Miranda, and Jonathan L. Curry

      11 Immunohistology of Leukemia Cutis and Histiocytic Tumors

      Maria Teresa Fernández Figueras, Gustavo Tapia, José Luis Mate, Aurelio Ariza

      Part VI: Immunohistology of Melanocytic Lesions

      12 Immunohistology of Melanocytic Lesions

      Jonathan L. Curry, Michael T. Tetzlaff, Priyadharsini Nagarajan, and Carlos A. Torres-Cabala

      Part VII: Molecular Studies of Melanocytic Lesions

      13 Molecular Studies of Melanocytic Lesions

      Rami Al-Rohil, Priyadharsini Nagarajan, and Michael T. Tetzlaff

      Part VIII: Immunohistology of Sentinel Lymph Node in Melanoma

      14 Sentinel Lymph Node in Melanoma

      Victor G. Prieto

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