Description
Book SynopsisIndispensable reference source for researchers in the pharmaceutical and allied industries, and at the biology/chemistry interface in academia.
Table of ContentsEditor's preface. Part 1 Amino acids: textbooks and reviews; naturally occurring amino acids; chemical synthesis and resolution; physical and stereochemical studies of amino acids; chemical studies of amino acids; analytical methods. Part 2 Peptide synthesis. Part 3 Analogue and conformational studies on peptide hormones and other biologically active peptides: peptide-backbone modifications; conformationally restricted bridged analogues; dehydroamino acid analogues; enzyme inhibitors; side-chain interactions studied by residue; conformational information derived from physical methods. Part 4 Cyclic, modified and conjugated peptides: cyclic peptides; modified linear peptides; conjugate peptides. Part 5 Beta-lactam antibiotic chemistry: new natural products; biosynthesis; penicillins and cephalosporins; penems; carbapenems and related systems; azetidinones; major structural variants; mechanistic studies on mode of action and degradation. Part 6 Metal complexes of amino acids and peptides.
