Description
Book SynopsisUsed in the production of a wide number of fine chemicals and pharmaceuticals, the Friedel-Crafts acylation reaction represents a synthetic process of great interest to organic chemists of academia and industry. Nearly 40 years since the last major treatise on the topic and reflecting the growing emphasis on green technology, Advances in Friedel-Crafts Acylation Reactions: Catalytic and Green Processes focuses on how to make this reaction more economically and environmentally friendly by using green acylating conditions, thus minimizing the formation of waste and decreasing production costs.
Divided into four parts, the book explores stoichiometric acylations, catalytic homogeneous acylations, catalytic heterogeneous acylations, and phenol acylations. It is structured according to the role played by the catalyst in the activation of reagents as well as in the different modes of regioselectivity encountered in the acylation of arenes, a
Trade Review
The Friedel-Crafts acylation reaction is of interest to organic chemists in academia and industry. This work reviews the most important research on the Friedel-Crafts acylation reaction published during the past 30 years, and demonstrates how to make this reaction more economical and less damaging to the environment.
—Book News, June 2010
The book is well structured and provides the reader with up-to-date references … New researchers in the field as well as expert industrial practitioners will find valuable insights and up-to-date references here. I would personally recommend this book to all colleagues and graduate-level students who are pursuing research in the field of synthetic manipulation of aromatic compounds, A perfect balance between historical background and new trends toward low-impact environmental strategies can be found throughout the book.
—Marco Bandini, Università di Bologna, Journal of the American Chemical Society, Vol. 132 Issue 21-24, 2010
Table of ContentsIntroduction and Scope. Stoichiometric Acylations. Catalytic Homogeneous Acylations. Catalytic Heterogeneous Acylations. Direct Phenol Acylation – Fries Rearrangement.
