{"product_id":"ultrastructural-pathology-9780813803302","title":"Ultrastructural Pathology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eUltrastructural Pathology, Second Edition\u003c\/i\u003e is a comprehensive reference on electron microscopy of pathologic tissue in animals and humans. Now presented in an atlas format for easier identification of organelles, the text is designed to bridge the gap between what is seen in the electron microscope at the cellular level and what the pathologist encounters in the postmortem room. New to this edition are sections on diagnostic electron microscopy, providing information on specialized technologies for electron microscopy, and invertebrate pathology. Emphasizing comparative pathology, the book explains and integrates all aspects of cellular changes in lesions occurring from natural or experimental disease.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"The reorganization of the book, with complete tables of infectious agents and updated references, and the addition of illustrations to display complex cellular processes contribute to the book's value as a reference text. I highly recommend this book as a valuable resource for students, researchers, pathologists, and veterinary health-care professionals.\" (\u003ci\u003eJournal of the American Veterinary Medical Association\u003c\/i\u003e, March 2010)\u003cbr\u003e \u003cbr\u003e  \"This atlas has something for everyone: the student preparing for pathology boards, the bench pathologist, the diagnostician, and the toxicologic pathologist, just to name a few. This book, like the first edition, will be the gold standard desk reference for anyone who needs to interpret or confirm cellular changes from surgical or postmortem lesions.\" (\u003ci\u003eMicroscopy \u0026amp; Microanalysis\u003c\/i\u003e, 2010)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003eContributors xiii\u003c\/p\u003e \u003cp\u003ePrologue xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I: Structural Basis of Cell Injury 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Response to Cellular Injury  5\u003c\/p\u003e \u003cp\u003eAcute Cell Swelling 5\u003c\/p\u003e \u003cp\u003eAdaptive Responses to Persistent Injury 21\u003c\/p\u003e \u003cp\u003e2 Cell Death 33\u003c\/p\u003e \u003cp\u003eNecrosis 35\u003c\/p\u003e \u003cp\u003eProgrammed Cell Death 40\u003c\/p\u003e \u003cp\u003eInterplay of Necrosis and PCD 49\u003c\/p\u003e \u003cp\u003eGetting Rid of the Dead Cell 52\u003c\/p\u003e \u003cp\u003eEndothelial Cell Death 54\u003c\/p\u003e \u003cp\u003e3 Cellular Defense and Recovery 61\u003c\/p\u003e \u003cp\u003ePlasma Membrane in Recovery 61\u003c\/p\u003e \u003cp\u003eDetoxification: Smooth Endoplasmic Reticulum and Peroxisomes 62\u003c\/p\u003e \u003cp\u003eMitochondria in Recovery 63\u003c\/p\u003e \u003cp\u003eNucleoli, DNA, and the Genome in Recovery 64\u003c\/p\u003e \u003cp\u003eProteostasis 67\u003c\/p\u003e \u003cp\u003eAutophagy: Removal of Debris 69\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II: Organelle Pathology 75\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4 The Cell Surface 77\u003c\/p\u003e \u003cp\u003eThe Plasma Membrane 77\u003c\/p\u003e \u003cp\u003eCytoskeleton 86\u003c\/p\u003e \u003cp\u003eIntercellular Junctions 97\u003c\/p\u003e \u003cp\u003eSurface Structures 101\u003c\/p\u003e \u003cp\u003e5 Intracellular Trafficking 109\u003c\/p\u003e \u003cp\u003eEndocytosis 109\u003c\/p\u003e \u003cp\u003ePhagocytosis 115\u003c\/p\u003e \u003cp\u003eLysosomes and Cytoplasmic Trafficking 116\u003c\/p\u003e \u003cp\u003eExocytosis 118\u003c\/p\u003e \u003cp\u003e6 Nucleus, Ribosomes, the Golgi Complex, and Secretion 125\u003c\/p\u003e \u003cp\u003eNucleus 125\u003c\/p\u003e \u003cp\u003eRibosomes 136\u003c\/p\u003e \u003cp\u003eRough Endoplasmic Reticulum 138\u003c\/p\u003e \u003cp\u003eGolgi Complex 139\u003c\/p\u003e \u003cp\u003eSecretion 142\u003c\/p\u003e \u003cp\u003e7 Peroxisomes, Smooth Endoplasmic Reticulum, and Lipids 153\u003c\/p\u003e \u003cp\u003ePeroxisomes 153\u003c\/p\u003e \u003cp\u003eSmooth Endoplasmic Reticulum 156\u003c\/p\u003e \u003cp\u003eGlycogen 161\u003c\/p\u003e \u003cp\u003eLipids 164\u003c\/p\u003e \u003cp\u003eLipoproteins 169\u003c\/p\u003e \u003cp\u003eLipid Metabolism Disorders 173\u003c\/p\u003e \u003cp\u003e8 Mitochondria 181\u003c\/p\u003e \u003cp\u003eThe Normal Mitochondrion 181\u003c\/p\u003e \u003cp\u003eMitochondrial Swelling: Response to Acute Injury 184\u003c\/p\u003e \u003cp\u003eMitochondriopathy of Metabolic and Chronic Diseases 188\u003c\/p\u003e \u003cp\u003eMitochondrial DNA-Based Disorders 193\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III: Inflammation and Hemostasis 199\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9 Endothelium 201\u003c\/p\u003e \u003cp\u003eEndothelial Interface with Blood and Perivascular Space 201\u003c\/p\u003e \u003cp\u003eEndothelial Thromboresistance vs. Procoagulation 206\u003c\/p\u003e \u003cp\u003eEndothelial Response to Hypoxia and Circulatory Dysfunction 208\u003c\/p\u003e \u003cp\u003eInflammation 209\u003c\/p\u003e \u003cp\u003eMast Cell and Basophil Interface with Endothelium 217\u003c\/p\u003e \u003cp\u003eAngiogenesis 223\u003c\/p\u003e \u003cp\u003e10 Leukocytes and Platelets 231\u003c\/p\u003e \u003cp\u003eThe Neutrophil 231\u003c\/p\u003e \u003cp\u003eEosinophils 243\u003c\/p\u003e \u003cp\u003ePlatelets 246\u003c\/p\u003e \u003cp\u003eThrombosis 257\u003c\/p\u003e \u003cp\u003e11 The Mononuclear Phagocyte System and Lymphocytes 269\u003c\/p\u003e \u003cp\u003eThe Monocyte-Macrophage System 269\u003c\/p\u003e \u003cp\u003eDendritic Cells 274\u003c\/p\u003e \u003cp\u003eLymphocytes 283\u003c\/p\u003e \u003cp\u003e12 The Extracellular Matrix 295\u003c\/p\u003e \u003cp\u003eCollagen Fibers 297\u003c\/p\u003e \u003cp\u003eMicrofibrils 303\u003c\/p\u003e \u003cp\u003eExtracellular Ground Substance 304\u003c\/p\u003e \u003cp\u003eBasement Membranes 307\u003c\/p\u003e \u003cp\u003eMucins and Other Barriers 310\u003c\/p\u003e \u003cp\u003ePart IV: Infectious Diseases 317\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Cytopathology of Viral Diseases 319\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFamily Poxviridae 319\u003c\/p\u003e \u003cp\u003eFamily Herpesviridae 327\u003c\/p\u003e \u003cp\u003eFamily Adenoviridae 338\u003c\/p\u003e \u003cp\u003eFamily Papillomaviridae 343\u003c\/p\u003e \u003cp\u003eFamily Polyomaviridae 347\u003c\/p\u003e \u003cp\u003eFamily Parvoviridae 349\u003c\/p\u003e \u003cp\u003eFamily Iridoviridae 353\u003c\/p\u003e \u003cp\u003eFamily Asfarviridae 353\u003c\/p\u003e \u003cp\u003eFamily Hepadnaviridae 354\u003c\/p\u003e \u003cp\u003eFamily Circoviridae 355\u003c\/p\u003e \u003cp\u003eFamily Orthomyxoviridae 356\u003c\/p\u003e \u003cp\u003eFamily Paramyxoviridae 358\u003c\/p\u003e \u003cp\u003eFamily Rhabdoviridae 366\u003c\/p\u003e \u003cp\u003eFamily Filoviridae 369\u003c\/p\u003e \u003cp\u003eFamily Coronaviridae 370\u003c\/p\u003e \u003cp\u003eFamily Reoviridae 373\u003c\/p\u003e \u003cp\u003eFamily Arenaviridae 379\u003c\/p\u003e \u003cp\u003eFamily Togaviridae 381\u003c\/p\u003e \u003cp\u003eFamily Arteriviridae 384\u003c\/p\u003e \u003cp\u003eFamily Bornaviridae 386\u003c\/p\u003e \u003cp\u003eFamily Flaviviridae 386\u003c\/p\u003e \u003cp\u003eFamily Bunyaviridae 391\u003c\/p\u003e \u003cp\u003eFamily Birnaviridae 392\u003c\/p\u003e \u003cp\u003eFamily Nadoviridae 394\u003c\/p\u003e \u003cp\u003eFamily Picornaviridae 394\u003c\/p\u003e \u003cp\u003eFamily Caliciviridae 399\u003c\/p\u003e \u003cp\u003eFamily Astroviridae 401\u003c\/p\u003e \u003cp\u003eFamily Retroviridae 401\u003c\/p\u003e \u003cp\u003e14 Cytopathology of Pathogenic Prokaryotes 425\u003c\/p\u003e \u003cp\u003eStructure of the Bacterial Cell 425\u003c\/p\u003e \u003cp\u003ePhylum Tenericutes, Order Mycoplasmatales 442\u003c\/p\u003e \u003cp\u003eOrder Entomoplasmatales 447\u003c\/p\u003e \u003cp\u003eOrder Incertae Sedis 447\u003c\/p\u003e \u003cp\u003ePhylum Proteobacteriae, Order Rickettsiales 448\u003c\/p\u003e \u003cp\u003eOrder Rhizobiales 453\u003c\/p\u003e \u003cp\u003eOrder Burkholderiales 457\u003c\/p\u003e \u003cp\u003eOrder Neisseriales 459\u003c\/p\u003e \u003cp\u003eOrder Campylobacterales 461\u003c\/p\u003e \u003cp\u003eOrder Aeromonadales 466\u003c\/p\u003e \u003cp\u003eOrder Enterobacteriales 466\u003c\/p\u003e \u003cp\u003eOrder Legionellales 476\u003c\/p\u003e \u003cp\u003eOrder Pasteurellales 477\u003c\/p\u003e \u003cp\u003eOrder Pseudomonadales 482\u003c\/p\u003e \u003cp\u003eOrder Thiotricales 484\u003c\/p\u003e \u003cp\u003eOrder Vibrionales 484\u003c\/p\u003e \u003cp\u003ePhylum Chlamydiae, Order Chlamydiales 485\u003c\/p\u003e \u003cp\u003eOrder Actinomycetales 487\u003c\/p\u003e \u003cp\u003ePhylum Firmicutes, Order Bacillales 496\u003c\/p\u003e \u003cp\u003eOrder Lactobacillales 500\u003c\/p\u003e \u003cp\u003eOrder Clostridiales 502\u003c\/p\u003e \u003cp\u003eOrder Spriochaetales 505\u003c\/p\u003e \u003cp\u003eOrder Bacteroidales 509\u003c\/p\u003e \u003cp\u003eOrder Fusobacteriales 510\u003c\/p\u003e \u003cp\u003eOther Bacteria 510\u003c\/p\u003e \u003cp\u003e15 Pathogenic Protozoa 525\u003c\/p\u003e \u003cp\u003eAmoebas 526\u003c\/p\u003e \u003cp\u003eCiliates 528\u003c\/p\u003e \u003cp\u003eFlagellates 529\u003c\/p\u003e \u003cp\u003eHemosporidians 538\u003c\/p\u003e \u003cp\u003eThe Malarial Organisms 543\u003c\/p\u003e \u003cp\u003eThe Coccidia 549\u003c\/p\u003e \u003cp\u003eThe Microsporans 560\u003c\/p\u003e \u003cp\u003eProtozoa of Uncertain Taxonomy 563\u003c\/p\u003e \u003cp\u003e16 Algae, Fungi, and Other Eukaryotes 573\u003c\/p\u003e \u003cp\u003eAlgae 573\u003c\/p\u003e \u003cp\u003eFungi 576\u003c\/p\u003e \u003cp\u003eThe Myxozoans 595\u003c\/p\u003e \u003cp\u003eIntracelllar Metazoan Parasites 597\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V: Toxicologic Diseases 605\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17 Toxicologic Pathology 607\u003c\/p\u003e \u003cp\u003eLysosomotropic Hepatotoxins 609\u003c\/p\u003e \u003cp\u003eRough Endoplasmic Reticulum Hepatotoxins 613\u003c\/p\u003e \u003cp\u003eHepatotoxins and the Golgi Complex 619\u003c\/p\u003e \u003cp\u003eSmooth Endoplasmic Reticulum and Hepatotoxicity 619\u003c\/p\u003e \u003cp\u003eMitochondrial Hepatotoxins 623\u003c\/p\u003e \u003cp\u003eSteatosis and Hepatotoxicity 626\u003c\/p\u003e \u003cp\u003eHepatic Toxins That Act on the Nucleus 626\u003c\/p\u003e \u003cp\u003eHepatocyte Toxins That Act on the Cytoskeleton 627\u003c\/p\u003e \u003cp\u003eParticulate Hepatotoxins 627\u003c\/p\u003e \u003cp\u003e18 Myotoxins 635\u003c\/p\u003e \u003cp\u003eCardiotoxicity 635\u003c\/p\u003e \u003cp\u003eMyocardial Toxins 643\u003c\/p\u003e \u003cp\u003eSkeletal Muscle 651\u003c\/p\u003e \u003cp\u003eSmooth Muscle Toxicity 658\u003c\/p\u003e \u003cp\u003e19 Neurotoxins and Neurodegeneration 667\u003c\/p\u003e \u003cp\u003eIntroduction 667\u003c\/p\u003e \u003cp\u003eNeuronopathies 668\u003c\/p\u003e \u003cp\u003eMyelin Toxins: Myelinopathies 678\u003c\/p\u003e \u003cp\u003eNeuropathies: The Peripheral Nerves 681\u003c\/p\u003e \u003cp\u003eNeurotoxins That Act at Nerve Termini and Synapses 683\u003c\/p\u003e \u003cp\u003eGlial Toxins 687\u003c\/p\u003e \u003cp\u003eVascular Neurotoxins and the Blood-Brain Barrier 688\u003c\/p\u003e \u003cp\u003e20 Nephrotoxins 695\u003c\/p\u003e \u003cp\u003eGlomerular Toxins 695\u003c\/p\u003e \u003cp\u003eProximal Convoluted Tubule Toxins 697\u003c\/p\u003e \u003cp\u003eDistal Tubule Toxins 705\u003c\/p\u003e \u003cp\u003eToxins in the Medulla 705\u003c\/p\u003e \u003cp\u003eThe Juxtaglomerular Apparatus 708\u003c\/p\u003e \u003cp\u003eCrystal Nephropathy 710\u003c\/p\u003e \u003cp\u003eConfounding Lesions in Nephrotoxicity 711\u003c\/p\u003e \u003cp\u003e21 Toxicity of Respiratory Systems 717\u003c\/p\u003e \u003cp\u003eThe Normal Mammalian Lung 717\u003c\/p\u003e \u003cp\u003eReaction to Pulmonary Toxins 719\u003c\/p\u003e \u003cp\u003eSubstances Damaging to Lung 723\u003c\/p\u003e \u003cp\u003eAcute Toxic Pulmonary Injury 726\u003c\/p\u003e \u003cp\u003eChronic Inhalant Injury 728\u003c\/p\u003e \u003cp\u003eChronic Exhalant Toxicity 734\u003c\/p\u003e \u003cp\u003eComparative Respiratory Systems 736\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VI: Pathologic Growth 741\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22 The Cell Cycle: Dysfunction in Aging, Senescence, and Hibernation 743\u003c\/p\u003e \u003cp\u003eThe Cell Cycle 743\u003c\/p\u003e \u003cp\u003eRegeneration 747\u003c\/p\u003e \u003cp\u003eAging and Senescence 750\u003c\/p\u003e \u003cp\u003eHibernation 751\u003c\/p\u003e \u003cp\u003eCell Senescence 752\u003c\/p\u003e \u003cp\u003e23 The Neoplastic Cell 757\u003c\/p\u003e \u003cp\u003eThe Genomic Landscape 758\u003c\/p\u003e \u003cp\u003eBenign or Malignant 761\u003c\/p\u003e \u003cp\u003eNeoplastic Cell Structure 761\u003c\/p\u003e \u003cp\u003eNeoplastic Cell Surfaces 763\u003c\/p\u003e \u003cp\u003eThe Nucleus of the Neoplastic Cell 766\u003c\/p\u003e \u003cp\u003eCytoplasm 769\u003c\/p\u003e \u003cp\u003eThe Tumor Microenvironment 775\u003c\/p\u003e \u003cp\u003eMetastasis 780\u003c\/p\u003e \u003cp\u003eNeoplastic Cell Death 785\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VII: Diagnostic Pathology 795\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e24 Calcification 797\u003c\/p\u003e \u003cp\u003eIntracellular Calcification 797\u003c\/p\u003e \u003cp\u003eExtracellular Calcification 798\u003c\/p\u003e \u003cp\u003eMicroliths 802\u003c\/p\u003e \u003cp\u003e25 Pigments 811\u003c\/p\u003e \u003cp\u003eMelanin 811\u003c\/p\u003e \u003cp\u003eChromatophores 815\u003c\/p\u003e \u003cp\u003eHemoglobin-Derived Pigments 815\u003c\/p\u003e \u003cp\u003eErythrophagocytosis 817\u003c\/p\u003e \u003cp\u003eCopper-Containing Pigments 822\u003c\/p\u003e \u003cp\u003eExogenous Pigments 824\u003c\/p\u003e \u003cp\u003e26 Amyloid, Protein Misfolding Defects, and Inclusions 829\u003c\/p\u003e \u003cp\u003eAmyloid 829\u003c\/p\u003e \u003cp\u003eTauopathies 839\u003c\/p\u003e \u003cp\u003eSynucleinopathies 840\u003c\/p\u003e \u003cp\u003eMisfolded Proteins and Inspissated Inclusions 842\u003c\/p\u003e \u003cp\u003e27 Metabolic and Storage Diseases 857\u003c\/p\u003e \u003cp\u003eLipid Storage Diseases 857\u003c\/p\u003e \u003cp\u003eNeuronal Ceroid Lipofuscinoses 862\u003c\/p\u003e \u003cp\u003eGlycoproteinoses 863\u003c\/p\u003e \u003cp\u003eMucopolysaccharidoses 864\u003c\/p\u003e \u003cp\u003eMucolipidoses 866\u003c\/p\u003e \u003cp\u003eGlycogen Storage Diseases 866\u003c\/p\u003e \u003cp\u003eAmino Acid Transport Storage Diseases 869\u003c\/p\u003e \u003cp\u003eOther Storage Diseases 870\u003c\/p\u003e \u003cp\u003e28 Arteriopathy 875\u003c\/p\u003e \u003cp\u003eResponses of the Artery to Injury 875\u003c\/p\u003e \u003cp\u003eAtherosclerosis 881\u003c\/p\u003e \u003cp\u003e29 The Renal Glomerulopathies 891\u003c\/p\u003e \u003cp\u003eMembranous Glomerulonephritis 891\u003c\/p\u003e \u003cp\u003eProliferative Glomerulonephritis 898\u003c\/p\u003e \u003cp\u003eMinimal Change Disease 900\u003c\/p\u003e \u003cp\u003eGlomerulonephritis Associated with Systemic Disease 900\u003c\/p\u003e \u003cp\u003eDiabetes 903\u003c\/p\u003e \u003cp\u003e30 Prions 911\u003c\/p\u003e \u003cp\u003ePrions Defi ned 911\u003c\/p\u003e \u003cp\u003eThe Transmissible Spongiform Encephalopathies 912\u003c\/p\u003e \u003cp\u003eIndex 917\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":53515497570647,"sku":"9780813803302","price":305.06,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/bookcurl.com\/products\/ultrastructural-pathology-9780813803302","provider":"Book Curl","version":"1.0","type":"link"}