{"product_id":"ubiquitin-proteasome-pathway-9781838804329","title":"Ubiquitin: Proteasome Pathway","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe ubiquitin-proteasome pathway consists of ubiquitin, substrate proteins, E1 enzymes, E2 enzymes, E3 enzymes, and proteasome, which acts in a series of enzymatic reaction chains to ubiquitinate substrate proteins such as surplus and misfolded proteins for degradation by the proteasome to maintain the balance between protein synthesis and degradation in a cell and tissue. Moreover, deubiquitinating enzymes can remove the attached ubiquitin chain, which results in a reverse ubiquitination-deubiquitination process involved in multiple biological processes in a cell and tissue. The changes of components in the ubiquitin-proteasome pathway are associated with multiple pathophysiological processes, such as cancers and neurodegenerative diseases. This book presents the new advances in concepts, analytical methodology, and application of ubiquitin-proteasome pathway for clarification of molecular mechanisms and discovery of new therapeutic targets and drugs in different diseases.","brand":"IntechOpen","offers":[{"title":"Default Title","offer_id":53191377060183,"sku":"9781838804329","price":107.1,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/ubiquitin-proteasome-pathway-9781838804329","provider":"Book Curl","version":"1.0","type":"link"}