{"product_id":"twodimensional-2d-nmr-methods-9781119806691","title":"TwoDimensional 2D NMR Methods","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eTWO-DIMENSIONAL (2D) NMR METHODS\u003c\/b\u003e \u003cp\u003e\u003cb\u003ePractical guide explaining the fundamentals of 2D-NMR for experienced scientists as well as relevant for advanced students\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eTwo-Dimensional (2D) NMR Methods\u003c\/i\u003e is a focused work presenting an overview of 2D-NMR concepts and techniques, including basic principles, practical applications, and how NMR pulse sequences work. \u003c\/p\u003e\u003cp\u003eContributed to by global experts with extensive experience in the field, \u003ci\u003eTwo-Dimensional (2D) NMR Methods\u003c\/i\u003e provides in-depth coverage of sample topics such as: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eBasics of 2D-NMR, data processing methods (Fourier and beyond), product operator formalism, basics of spin relaxation, and coherence transfer pathways\u003c\/li\u003e \u003cli\u003eMultidimensional methods (single- and multiple-quantum spectroscopy), NOESY (principles and applications), and DOSY methods\u003c\/li\u003e \u003cli\u003eMultiple acquisition strategies, anisotropic NMR in molecular analysis, ultrafast 2D methods, and multidimensional methods in bio-NMR\u003c\/li\u003e \u003cli\u003eTROSY (pr\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eDedication v\u003c\/p\u003e \u003cp\u003eList of Contributors xvii\u003c\/p\u003e \u003cp\u003ePreface xix\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Basics of Two-dimensional NMR 1\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMalcolm H. Levitt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e1.2 Spin Dynamics 2\u003c\/p\u003e \u003cp\u003e1.3 One-dimensional Fourier NMR 6\u003c\/p\u003e \u003cp\u003e1.4 Two-dimensional NMR 11\u003c\/p\u003e \u003cp\u003e1.5 Summary 14\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Data Processing Methods: Fourier and Beyond 19\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eVladislav Orekhov, Pawel Kasprzak, and Krzysztof Kazimierczuk\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 19\u003c\/p\u003e \u003cp\u003e2.2 Time-domain NMR Signal 19\u003c\/p\u003e \u003cp\u003e2.3 NMR Spectrum 20\u003c\/p\u003e \u003cp\u003e2.4 The Most Important Features of FT 20\u003c\/p\u003e \u003cp\u003e2.5 Distortion: Phase 23\u003c\/p\u003e \u003cp\u003e2.6 Kramers-Kronig Relations and Hilbert Transform 23\u003c\/p\u003e \u003cp\u003e2.7 Distortion: Truncation 25\u003c\/p\u003e \u003cp\u003e2.8 Distortion: Noise and Multiple Scans 27\u003c\/p\u003e \u003cp\u003e2.9 Distortion: Sampling and DFT 27\u003c\/p\u003e \u003cp\u003e2.10 Quadrature Detection 30\u003c\/p\u003e \u003cp\u003e2.11 Processing:Weighting 31\u003c\/p\u003e \u003cp\u003e2.12 Processing: Zero Filling 33\u003c\/p\u003e \u003cp\u003e2.13 Fourier Transform in Multiple Dimensions 33\u003c\/p\u003e \u003cp\u003e2.14 Quadrature Detection in Multiple Dimensions 36\u003c\/p\u003e \u003cp\u003e2.15 Projection Theorem 37\u003c\/p\u003e \u003cp\u003e2.16 ND Sampling Aspects and Sparse Sampling 40\u003c\/p\u003e \u003cp\u003e2.17 Reconstructing Sparsely Sampled Data Sets 41\u003c\/p\u003e \u003cp\u003e2.18 Deconvolution 42\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Product Operator Formalism 47\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eRolf Boelens and Robert Kaptein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 47\u003c\/p\u003e \u003cp\u003e3.2 Product Operators and Time Evolution 48\u003c\/p\u003e \u003cp\u003e3.3 Time Evolution of the Product Operators 55\u003c\/p\u003e \u003cp\u003e3.4 Applications 59\u003c\/p\u003e \u003cp\u003e3.4.1 Spin-echo Experiments 59\u003c\/p\u003e \u003cp\u003e3.5 Two-dimensional Experiments 66\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Relaxation in NMR Spectroscopy 93\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMatthias Ernst\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 93\u003c\/p\u003e \u003cp\u003e4.2 Theory 95\u003c\/p\u003e \u003cp\u003e4.3 Relaxation in Spin-1\/2 Systems: Dipolar and CSA Relaxation 104\u003c\/p\u003e \u003cp\u003e4.4 Other Relaxation Mechanisms 125\u003c\/p\u003e \u003cp\u003e4.5 Concluding Remarks 130\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Coherence Transfer Pathways 135\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eDavid E. Korenchan and Alexej Jerschow\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Coherence Transfer Pathways: What and Why? 135\u003c\/p\u003e \u003cp\u003e5.2 Principles of Coherence Selection 137\u003c\/p\u003e \u003cp\u003e5.3 Coherence Transfer Pathway Selection by Phase Cycling 140\u003c\/p\u003e \u003cp\u003e5.4 Cogwheel Phase Cycling 146\u003c\/p\u003e \u003cp\u003e5.5 Coherence Transfer Pathway Selection by Pulsed-field Gradients 147\u003c\/p\u003e \u003cp\u003e5.6 Comparison Between Phase Cycling and Pulsed-field Gradients 150\u003c\/p\u003e \u003cp\u003e5.7 CTP Selection in Heteronuclear Spin Systems 150\u003c\/p\u003e \u003cp\u003e5.8 Additional Approaches to Coherence Selection 151\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Nuclear Overhauser Effect Spectroscopy 153\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eP.K. Madhu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 153\u003c\/p\u003e \u003cp\u003e6.2 Nuclear Overhauser Effect 153\u003c\/p\u003e \u003cp\u003e6.3 Measurement of NOE 161\u003c\/p\u003e \u003cp\u003e6.4 Heteronuclear NOE 161\u003c\/p\u003e \u003cp\u003e6.5 NOE Kinetics 162\u003c\/p\u003e \u003cp\u003e6.6 Nuclear Overhauser Effect Spectroscopy, NOESY 164\u003c\/p\u003e \u003cp\u003e6.7 Rotating-frame NOE, ROE 166\u003c\/p\u003e \u003cp\u003e6.8 Relative Signs of Cross Peaks 168\u003c\/p\u003e \u003cp\u003e6.9 Generalised Solomon’s Equation 169\u003c\/p\u003e \u003cp\u003e6.10 NOESY and ROESY: Practical Considerations and Experimental Spectra 170\u003c\/p\u003e \u003cp\u003e6.11 Conclusions 170\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 DOSY Methods for Studying Non-equilibrium Molecular and Ionic Systems 175\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMuslim Dvoyashkin, Monika Schoönhoff, and Ville-Veikko Telkki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 175\u003c\/p\u003e \u003cp\u003e7.2 Spatial Spin \"Encoding\" Using Magnetic Field Gradient 175\u003c\/p\u003e \u003cp\u003e7.3 Formation of NMR Signal and Spin Echo in the Presence of Field Gradient 176\u003c\/p\u003e \u003cp\u003e7.4 NMR of Liquids in An Electric Field: Electrophoretic NMR 178\u003c\/p\u003e \u003cp\u003e7.5 Ultrafast Diffusion Measurements 186\u003c\/p\u003e \u003cp\u003e7.6 Ultrafast Diffusion Exchange Spectroscopy 189\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Multiple Acquisition Strategies 195\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eNathaniel J. Traaseth\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 195\u003c\/p\u003e \u003cp\u003e8.2 Types of Multiple Acquisition Experiments 195\u003c\/p\u003e \u003cp\u003e8.3 Utilization of Forgotten Spin Operators 196\u003c\/p\u003e \u003cp\u003e8.4 Application of Multiple Acquisition Techniques 198\u003c\/p\u003e \u003cp\u003e8.5 Modularity of Multiple Detection Schemes and Other Novel Approaches 201\u003c\/p\u003e \u003cp\u003e8.6 Future of Multiple Acquisition Detection 202\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Anisotropic One-dimensional\/Two-dimensional NMR in Molecular Analysis 209\u003c\/b\u003e\u003cbr\u003e\u003ci\u003ePhilippe Lesot and Roberto R. Gil\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 209\u003c\/p\u003e \u003cp\u003e9.2 Advantages of Oriented Solvents 210\u003c\/p\u003e \u003cp\u003e9.3 Description of Useful Anisotropic NMR Parameters 213\u003c\/p\u003e \u003cp\u003e9.4 Adapted 2D NMR Tools 221\u003c\/p\u003e \u003cp\u003e9.5 Examples of Polymeric Liquid Crystals 226\u003c\/p\u003e \u003cp\u003e9.6 Contribution to the Analysis of Chiral and Prochiral Molecules 232\u003c\/p\u003e \u003cp\u003e9.7 Structural Value of Anisotropic NMR Parameters 248\u003c\/p\u003e \u003cp\u003e9.8 Conformational Analysis in Oriented Solvents 276\u003c\/p\u003e \u003cp\u003e9.9 Anisotropic 2H 2D NMR Applied to Molecular Isotope Analysis 277\u003c\/p\u003e \u003cp\u003e9.10 Anisotropic NMR in Molecular Analysis: What You Should Keep in Mind 281\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Ultrafast 2D methods 297\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eBoris Gouilleux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 297\u003c\/p\u003e \u003cp\u003e10.2 UF 2D NMR Principles: Entangling the Space and the Time 299\u003c\/p\u003e \u003cp\u003e10.3 Specific Features of UF 2D NMR 305\u003c\/p\u003e \u003cp\u003e10.4 Advanced UF Methods 307\u003c\/p\u003e \u003cp\u003e10.5 UF 2D NMR: A Versatile Approach 311\u003c\/p\u003e \u003cp\u003e10.6 Overview of UF 2D NMR Applications 316\u003c\/p\u003e \u003cp\u003e10.7 Conclusion 326\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Multi-dimensional Methods in Biological NMR 333\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eTobias Schneider and Michael Kovermann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction 333\u003c\/p\u003e \u003cp\u003e11.2 Experimental Approaches 334\u003c\/p\u003e \u003cp\u003e11.3 Case Studies 338\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 TROSY: Principles and Applications 365\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eHarindranath Kadavath and Roland Riek\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 365\u003c\/p\u003e \u003cp\u003e12.2 The Principles of TROSY 366\u003c\/p\u003e \u003cp\u003e12.3 Practical Aspects of TROSY 371\u003c\/p\u003e \u003cp\u003e12.4 Applications of TROSY 374\u003c\/p\u003e \u003cp\u003e12.5 Transverse Relaxation-optimization in the Polarization Transfers 379\u003c\/p\u003e \u003cp\u003e12.6 15N Direct Detected TROSY 380\u003c\/p\u003e \u003cp\u003e12.7 [1H,13C]-TROSY Correlation Experiments 380\u003c\/p\u003e \u003cp\u003e12.8 Applications to Nucleic Acids 382\u003c\/p\u003e \u003cp\u003e12.9 Intermolecular Interactions and Drug Design 383\u003c\/p\u003e \u003cp\u003e12.10 Conclusion 383\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Two-Dimensional Methods and Zero- to Ultralow-Field (ZULF) NMR 395\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eK.L. Ivanov, John Blanchard, Dmitry Budker, Fabien Ferrage, Alexey Kiryutin, Tobias Sjolander, Alexandra Yurkovskaya, and Ivan Zhukov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction and Motivation 395\u003c\/p\u003e \u003cp\u003e13.2 EarlyWork 396\u003c\/p\u003e \u003cp\u003e13.3 Two-dimensional NMR Measured at Zero Magnetic Field 397\u003c\/p\u003e \u003cp\u003e13.4 Nuclear Magnetic Resonance at Millitesla Fields Using a Zero-Field Spectrometer 403\u003c\/p\u003e \u003cp\u003e13.5 Field Cycling NMR and Correlation Spectroscopy 404\u003c\/p\u003e \u003cp\u003e13.6 ZERO-Field - High-Field Comparison 409\u003c\/p\u003e \u003cp\u003e13.7 Conclusion and Outlook 412\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Multidimensional Methods and Paramagnetic NMR 415\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eThomas Robinson, Kevin J. Sanders, Andrew J. Pell, and Guido Pintacuda\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction 415\u003c\/p\u003e \u003cp\u003e14.2 NMR Methods for Paramagnetic Systems in Solution 416\u003c\/p\u003e \u003cp\u003e14.3 NMR Methods for Paramagnetic Systems in Solids 423\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Chemical Exchange 435\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAshok Sekhar and Pramodh Vallurupalli\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction 435\u003c\/p\u003e \u003cp\u003e15.2 Bloch-McConnell Equations 436\u003c\/p\u003e \u003cp\u003e15.3 Studying Exchange Between Visible States 443\u003c\/p\u003e \u003cp\u003e15.4 Studying Exchange Between a Visible State and Invisible State(s) 448\u003c\/p\u003e \u003cp\u003e15.5 Summary 458\u003c\/p\u003e \u003cp\u003eAcknowledgments 459\u003c\/p\u003e \u003cp\u003eReferences 459\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAppendix A Proton-Detected Heteronuclear and Multidimensional NMR 461\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eChristian Griesinger, Harald Schwalbe, Jürgen Schleucher, and Michael Sattler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 553\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49407158550871,"sku":"9781119806691","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119806691.jpg?v=1730498377","url":"https:\/\/bookcurl.com\/products\/twodimensional-2d-nmr-methods-9781119806691","provider":"Book Curl","version":"1.0","type":"link"}