{"product_id":"therapeutic-dressings-and-wound-healing-applications-9781119433262","title":"Therapeutic Dressings and Wound Healing","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing.    This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ? Debridement and disinfection properties of wound dressing ? Biofilms, silver nanoparticles, and honey dressings ? Clinical perspectives for treating diabetic wounds ? T\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of Contributors xiii\u003c\/p\u003e \u003cp\u003eSeries Preface xvii\u003c\/p\u003e \u003cp\u003ePreface xix\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Chronic Wound Healing: Molecular and Biochemical Basis 1\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eSophia Tate and Keith Harding\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e1.2 Acute Wound Healing 1\u003c\/p\u003e \u003cp\u003e1.3 Categories of Chronic Wound 3\u003c\/p\u003e \u003cp\u003e1.3.1 Pressure Ulcers 3\u003c\/p\u003e \u003cp\u003e1.3.2 Venous Stasis Ulcers 4\u003c\/p\u003e \u003cp\u003e1.3.3 Ischaemic Ulcers 4\u003c\/p\u003e \u003cp\u003e1.3.4 Diabetic Foot Ulcers 4\u003c\/p\u003e \u003cp\u003e1.4 How a Chronic Wound Develops: Intrinsic Components 4\u003c\/p\u003e \u003cp\u003e1.4.1 Cell Phenotype 5\u003c\/p\u003e \u003cp\u003e1.4.2 Immune Cells and Inflammatory Mediators 6\u003c\/p\u003e \u003cp\u003e1.4.3 Reactive Oxygen Species 8\u003c\/p\u003e \u003cp\u003e1.4.4 Growth Factors 8\u003c\/p\u003e \u003cp\u003e1.4.5 The Role of Matrix Metalloproteinases 12\u003c\/p\u003e \u003cp\u003e1.5 How a Chronic Wound Develops: Extrinsic Factors 13\u003c\/p\u003e \u003cp\u003e1.5.1 Infection 13\u003c\/p\u003e \u003cp\u003e1.5.2 Nutrition 13\u003c\/p\u003e \u003cp\u003e1.5.3 Tobacco Smoking 14\u003c\/p\u003e \u003cp\u003e1.5.4 Hypoxia and Ischaemia–Reperfusion Injury 15\u003c\/p\u003e \u003cp\u003e1.6 Concluding Remarks 15\u003c\/p\u003e \u003cp\u003eReferences 16\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Clinical Perspectives for Treating Chronic Wounds 21\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eBarun Majumder, Kirstie Lane, Diane Beck, Sandeep Singh and Duniya Majumder\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Background 21\u003c\/p\u003e \u003cp\u003e2.2 Aetiology of Diabetic Foot Ulcers 22\u003c\/p\u003e \u003cp\u003e2.3 Standard of Care for Treatment of Diabetic Foot Ulcers 22\u003c\/p\u003e \u003cp\u003e2.4 Commonly Used Wound Dressings for Diabetic Foot Ulcers and Their Mechanism of Action 22\u003c\/p\u003e \u003cp\u003e2.5 Absorbent and Superabsorbent Dressings 23\u003c\/p\u003e \u003cp\u003e2.6 Alginates 23\u003c\/p\u003e \u003cp\u003e2.7 Films 23\u003c\/p\u003e \u003cp\u003e2.8 Foams 24\u003c\/p\u003e \u003cp\u003e2.9 Honeys 24\u003c\/p\u003e \u003cp\u003e2.10 Hydrogels 25\u003c\/p\u003e \u003cp\u003e2.11 The Role of a Split Thickness Skin Graft in Diabetic Foot Ulcers 25\u003c\/p\u003e \u003cp\u003e2.12 Negative Pressure Wound Therapy 25\u003c\/p\u003e \u003cp\u003e2.13 Larval Therapy 27\u003c\/p\u003e \u003cp\u003e2.14 Clinical Case Studies from Multidisciplinary Diabetic Foot Clinic 27\u003c\/p\u003e \u003cp\u003e2.14.1 Neuropathic Wound 27\u003c\/p\u003e \u003cp\u003e2.14.2 Ischaemic Wound 29\u003c\/p\u003e \u003cp\u003e2.14.3 Neuro-Ischaemic Wound 31\u003c\/p\u003e \u003cp\u003e2.14.4 Osteomyelitis 33\u003c\/p\u003e \u003cp\u003e2.14.5 Charcot’s Foot 35\u003c\/p\u003e \u003cp\u003e2.14.6 Necrotising Fasciitis in a Patient with Diabetes 36\u003c\/p\u003e \u003cp\u003e2.15 Summary 39\u003c\/p\u003e \u003cp\u003eAcknowledgements 39\u003c\/p\u003e \u003cp\u003eReferences 39\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Prediction, Prevention, Assessment, and Management of Skin Tears in the Aging Population 43\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eKimberly LeBlanc and Karen Campbell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 43\u003c\/p\u003e \u003cp\u003e3.2 Skin Tear Prevalence and Incidence 44\u003c\/p\u003e \u003cp\u003e3.3 Predicting Skin Tears 45\u003c\/p\u003e \u003cp\u003e3.4 Prevention 47\u003c\/p\u003e \u003cp\u003e3.5 ISTAP Risk Reduction Program 49\u003c\/p\u003e \u003cp\u003e3.5.1 General Health 49\u003c\/p\u003e \u003cp\u003e3.5.2 Mobility 50\u003c\/p\u003e \u003cp\u003e3.5.3 Skin 51\u003c\/p\u003e \u003cp\u003e3.6 Assessment 52\u003c\/p\u003e \u003cp\u003e3.7 Management 54\u003c\/p\u003e \u003cp\u003e3.8 Treatment 54\u003c\/p\u003e \u003cp\u003e3.9 Conclusion 55\u003c\/p\u003e \u003cp\u003eReferences 55\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Importance of Debriding and Wound Cleansing Agents in Wound Healing 59\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGwendolyn Cazander, Bianca K. den Ottelander, Sandra Kamga, Martijn C.H.A. Doomen, Tim H.C. Damen and Anne Marie E. van Well\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 What is Debridement? 59\u003c\/p\u003e \u003cp\u003e4.2 The History of Debridement 59\u003c\/p\u003e \u003cp\u003e4.3 Why Undertake Debridement? 60\u003c\/p\u003e \u003cp\u003e4.4 Debridement Techniques and Wound Cleansing Agents 62\u003c\/p\u003e \u003cp\u003e4.4.1 Mechanical Debridement 62\u003c\/p\u003e \u003cp\u003e4.4.2 Biological Debridement 72\u003c\/p\u003e \u003cp\u003e4.4.3 Enzymatic Debridement 74\u003c\/p\u003e \u003cp\u003e4.4.4 Autolytic Debridement 77\u003c\/p\u003e \u003cp\u003e4.4.5 Wound Cleansing 79\u003c\/p\u003e \u003cp\u003e4.4.6 Other Debridement Therapies 80\u003c\/p\u003e \u003cp\u003e4.5 What is the Future of Debridement? 81\u003c\/p\u003e \u003cp\u003eReferences 82\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Treatment of Mixed Infections in Wounds 91\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAsif Ahmed and Joshua Boateng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 91\u003c\/p\u003e \u003cp\u003e5.1.1 Wound Healing Process 92\u003c\/p\u003e \u003cp\u003e5.1.2 Types of Chronic Wounds 92\u003c\/p\u003e \u003cp\u003e5.2 Prevalence of Mixed Infections 94\u003c\/p\u003e \u003cp\u003e5.2.1 Bacterial–Fungal Interactions 95\u003c\/p\u003e \u003cp\u003e5.2.2 Bacterial–Bacterial Interactions 98\u003c\/p\u003e \u003cp\u003e5.2.3 Host Responses to Mixed Infections and Drug Resistance 99\u003c\/p\u003e \u003cp\u003e5.3 Management of Mixed Infected Wounds 100\u003c\/p\u003e \u003cp\u003e5.3.1 Clinical and Microbiological Diagnosis 101\u003c\/p\u003e \u003cp\u003e5.3.2 Debridement and Cleansing 101\u003c\/p\u003e \u003cp\u003e5.3.3 Antimicrobial Therapies 102\u003c\/p\u003e \u003cp\u003e5.3.4 Hyperbaric Oxygen Therapy 104\u003c\/p\u003e \u003cp\u003e5.3.5 Phage Therapy 104\u003c\/p\u003e \u003cp\u003e5.4 Summary and Future Perspectives 104\u003c\/p\u003e \u003cp\u003eReferences 105\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Treatment of Biofilms in Infected Wounds 115\u003cbr\u003e\u003c\/b\u003e\u003ci\u003ePhilip Debrah, Awo Afi Kwapong and Mansa Fredua-Agyeman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 115\u003c\/p\u003e \u003cp\u003e6.2 Why and How Biofilms Form 116\u003c\/p\u003e \u003cp\u003e6.3 Wound Biofilms 118\u003c\/p\u003e \u003cp\u003e6.3.1 Wound Healing 119\u003c\/p\u003e \u003cp\u003e6.4 Biofilms and Wounds 119\u003c\/p\u003e \u003cp\u003e6.4.1 Simulation of Biofilms in Wounds 120\u003c\/p\u003e \u003cp\u003e6.5 Treatment of Biofilms in Wounds 126\u003c\/p\u003e \u003cp\u003e6.5.1 Biofilm Eradication 126\u003c\/p\u003e \u003cp\u003e6.5.2 Current Treatment Protocols 128\u003c\/p\u003e \u003cp\u003e6.6 Clinical Examples 128\u003c\/p\u003e \u003cp\u003e6.7 Summary 128\u003c\/p\u003e \u003cp\u003eReferences 130\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Freeze-Dried Wafers for Wound Healing 137\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eShiow-Fern Ng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 137\u003c\/p\u003e \u003cp\u003e7.2 Wafer as a Modern Wound Dressing 138\u003c\/p\u003e \u003cp\u003e7.3 Freeze-Drying Process 139\u003c\/p\u003e \u003cp\u003e7.4 Wafer Preparation 140\u003c\/p\u003e \u003cp\u003e7.5 Wafer Assessments 141\u003c\/p\u003e \u003cp\u003e7.5.1 Morphology 142\u003c\/p\u003e \u003cp\u003e7.5.2 Swelling Index 144\u003c\/p\u003e \u003cp\u003e7.5.3 Mechanical Properties 145\u003c\/p\u003e \u003cp\u003e7.5.4 In Vitro Drug Release 145\u003c\/p\u003e \u003cp\u003e7.5.5 Cell Viability 146\u003c\/p\u003e \u003cp\u003e7.6 Wafer Biopolymers 146\u003c\/p\u003e \u003cp\u003e7.6.1 Alginate 147\u003c\/p\u003e \u003cp\u003e7.6.2 Chitosan 148\u003c\/p\u003e \u003cp\u003e7.6.3 Carboxymethylcellulose 149\u003c\/p\u003e \u003cp\u003e7.7 Conclusion 150\u003c\/p\u003e \u003cp\u003eReferences 150\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Silver and Silver Nanoparticle-Based Antimicrobial Dressings 157\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJoshua Boateng and Ovidio Catanzano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 157\u003c\/p\u003e \u003cp\u003e8.1.1 Brief History of Silver as an Antibiotic 159\u003c\/p\u003e \u003cp\u003e8.1.2 Mechanism of Action 160\u003c\/p\u003e \u003cp\u003e8.1.3 Bacterial Resistance to Silver 164\u003c\/p\u003e \u003cp\u003e8.2 Silver Dressings in Wound Healing 167\u003c\/p\u003e \u003cp\u003e8.2.1 Silver-Based Antimicrobial Dressings 169\u003c\/p\u003e \u003cp\u003e8.2.2 Silver Nanoparticle-Based Antimicrobial Dressings 170\u003c\/p\u003e \u003cp\u003e8.3 Cost-Effectiveness of Silver Dressings 175\u003c\/p\u003e \u003cp\u003e8.4 Concluding Remarks 176\u003c\/p\u003e \u003cp\u003eReferences 177\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Hydrogel Dressings 185\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGaliya S. Irmukhametova, Grigoriy A. Mun and Vitaliy V. Khutoryanskiy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 185\u003c\/p\u003e \u003cp\u003e9.1.1 Classification by Origin of Materials Used to Prepare Hydrogels 186\u003c\/p\u003e \u003cp\u003e9.1.2 Classification by Composition and Structure of Hydrogels 186\u003c\/p\u003e \u003cp\u003e9.1.3 Classification by the Type of Cross-Linking 187\u003c\/p\u003e \u003cp\u003e9.1.4 Classification Based on the Shape and Dimensions of Hydrogels 187\u003c\/p\u003e \u003cp\u003e9.1.5 Classification Based on the Charge of Macromolecules Forming Hydrogels 187\u003c\/p\u003e \u003cp\u003e9.1.6 Classification Based on Functional Properties of the Hydrogels 187\u003c\/p\u003e \u003cp\u003e9.2 Mechanism of Hydrogel Swelling 187\u003c\/p\u003e \u003cp\u003e9.2.1 Swelling of Temperature-Sensitive Hydrogels and Their Application in Wound Healing 189\u003c\/p\u003e \u003cp\u003e9.2.2 Swelling of Light-Sensitive Hydrogels 190\u003c\/p\u003e \u003cp\u003e9.2.3 Swelling of Electro-Sensitive Hydrogels 191\u003c\/p\u003e \u003cp\u003e9.3 Application of Hydrogels as Wound Dressings 191\u003c\/p\u003e \u003cp\u003e9.4 Industrial Methods for the Synthesis of Hydrogels for Wound Dressings 193\u003c\/p\u003e \u003cp\u003e9.4.1 Polymerization Methods 193\u003c\/p\u003e \u003cp\u003e9.4.2 Cross-Linking of Polymers 195\u003c\/p\u003e \u003cp\u003e9.5 Antimicrobial Hydrogels with Special Additives 198\u003c\/p\u003e \u003cp\u003e9.6 Conclusion 200\u003c\/p\u003e \u003cp\u003eAcknowledgments 201\u003c\/p\u003e \u003cp\u003eReferences 201\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Gene Therapy for the Treatment of Chronic Wounds 209\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMarcos Garcia-Fuentes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 209\u003c\/p\u003e \u003cp\u003e10.2 Pharmacodynamics of Gene Therapy in Chronic Wounds 210\u003c\/p\u003e \u003cp\u003e10.2.1 Signalling Supplementation 210\u003c\/p\u003e \u003cp\u003e10.2.2 Pathway Inhibition 211\u003c\/p\u003e \u003cp\u003e10.3 Administration Routes and Methods 212\u003c\/p\u003e \u003cp\u003e10.3.1 Systemic Delivery 212\u003c\/p\u003e \u003cp\u003e10.3.2 Topical Delivery 212\u003c\/p\u003e \u003cp\u003e10.3.3 Intralesional Delivery 213\u003c\/p\u003e \u003cp\u003e10.4 Gene Delivery Systems 213\u003c\/p\u003e \u003cp\u003e10.4.1 Physical Methods 214\u003c\/p\u003e \u003cp\u003e10.4.2 Viral Vectors 215\u003c\/p\u003e \u003cp\u003e10.4.3 Chemical Delivery Systems 217\u003c\/p\u003e \u003cp\u003e10.4.4 Gene-Activated Matrices 220\u003c\/p\u003e \u003cp\u003e10.5 Clinical Evaluation 221\u003c\/p\u003e \u003cp\u003e10.6 Conclusion 226\u003c\/p\u003e \u003cp\u003eAcknowledgements 226\u003c\/p\u003e \u003cp\u003eReferences 227\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Honey in Wound Healing 235\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eEmi Maruhashi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 The History of Honey 235\u003c\/p\u003e \u003cp\u003e11.2 Composition 236\u003c\/p\u003e \u003cp\u003e11.3 Honey Research 236\u003c\/p\u003e \u003cp\u003e11.4 Medical Grade Honey 237\u003c\/p\u003e \u003cp\u003e11.5 Modes of Action 238\u003c\/p\u003e \u003cp\u003e11.6 Applications and Specific Wound Types 242\u003c\/p\u003e \u003cp\u003e11.7 Practical Considerations 246\u003c\/p\u003e \u003cp\u003e11.8 Novel Concepts and Conclusions 247\u003c\/p\u003e \u003cp\u003eReferences 248\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Regeneration Using Tissue Engineered Skin Strategies 255\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eLucília P. da Silva, Mariana T. Cerqueira and Alexandra P. Marques\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 255\u003c\/p\u003e \u003cp\u003e12.2 Skin Physiology and Wounding 256\u003c\/p\u003e \u003cp\u003e12.3 Skin Tissue Engineering 258\u003c\/p\u003e \u003cp\u003e12.4 Evolving Skin Tissue Engineering Strategies 259\u003c\/p\u003e \u003cp\u003e12.4.1 Balancing the Inflammatory Phase 261\u003c\/p\u003e \u003cp\u003e12.4.2 Enhancement of Re-Epithelialization 263\u003c\/p\u003e \u003cp\u003e12.4.3 Target of Dermal Matrix Synthesis and Remodeling 269\u003c\/p\u003e \u003cp\u003e12.4.4 Re-Establishment of the Vascular Network 270\u003c\/p\u003e \u003cp\u003e12.4.5 Innervation Shaping 280\u003c\/p\u003e \u003cp\u003e12.4.6 Appendages and Pigmentation 281\u003c\/p\u003e \u003cp\u003e12.5 Conclusion 282\u003c\/p\u003e \u003cp\u003eReferences 283\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Local Delivery of Growth Factors Using Wound Dressings 291\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eOvidio Catanzano and Joshua Boateng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Wound Dressings as Delivery Platforms for Growth Factors 291\u003c\/p\u003e \u003cp\u003e13.2 Growth Factors Involved in the Wound Healing Process 292\u003c\/p\u003e \u003cp\u003e13.3 Local Delivery of Growth Factors Using Wound Dressings 296\u003c\/p\u003e \u003cp\u003e13.4 Integration of Platelet-Rich Plasma in Wound Dressings 299\u003c\/p\u003e \u003cp\u003e13.5 Enhancing Local Growth Factor Expression Using Gene Therapy 300\u003c\/p\u003e \u003cp\u003e13.6 Wound Delivery of Growth Factors from Living Systems 302\u003c\/p\u003e \u003cp\u003e13.7 Regulatory Considerations 305\u003c\/p\u003e \u003cp\u003e13.8 Conclusions and Future Perspectives 306\u003c\/p\u003e \u003cp\u003eReferences 307\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Electrospinning Technologies in Wound Dressing Applications 315\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGiuseppina Sandri, Silvia Rossi, Maria Cristina Bonferoni, Carla Caramella and Franca Ferrari\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction 315\u003c\/p\u003e \u003cp\u003e14.2 Basic Concept and Electrospinning Set-Up 316\u003c\/p\u003e \u003cp\u003e14.3 Parameters Affecting the Electrospinning Process 318\u003c\/p\u003e \u003cp\u003e14.4 Process Parameters 319\u003c\/p\u003e \u003cp\u003e14.4.1 Electric Field Strength 319\u003c\/p\u003e \u003cp\u003e14.4.2 Flow Rate 319\u003c\/p\u003e \u003cp\u003e14.4.3 Needle-to-Collector Distance 320\u003c\/p\u003e \u003cp\u003e14.4.4 Collector and Needle Types 320\u003c\/p\u003e \u003cp\u003e14.5 Solution Parameters 321\u003c\/p\u003e \u003cp\u003e14.5.1 Molecular Weight and Polymer Concentration 321\u003c\/p\u003e \u003cp\u003e14.5.2 Surface Tension 322\u003c\/p\u003e \u003cp\u003e14.5.3 Conductivity\/Surface Charge Density 322\u003c\/p\u003e \u003cp\u003e14.5.4 Environmental Parameters 322\u003c\/p\u003e \u003cp\u003e14.6 Biomedical Applications of Nanofibrous Membranes 323\u003c\/p\u003e \u003cp\u003e14.6.1 Wound Dressings and Wound Healing 323\u003c\/p\u003e \u003cp\u003e14.6.2 Electrospun Dressings 325\u003c\/p\u003e \u003cp\u003e14.7 Chemicophysical and Biopharmaceutical Characterizations 325\u003c\/p\u003e \u003cp\u003e14.8 Dressing\/Scaffold Parameters Affecting Cell Functions 327\u003c\/p\u003e \u003cp\u003e14.9 Materials for Fabricating Nanofibers 328\u003c\/p\u003e \u003cp\u003e14.9.1 Biopolymers 328\u003c\/p\u003e \u003cp\u003e14.10 Concluding Remarks 333\u003c\/p\u003e \u003cp\u003eReferences 333\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 The Place of Biomaterials in Wound Healing 337\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAnnalisa Bianchera, Ovidio Catanzano, Joshua Boateng and Lisa Elviri\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction to Biomaterials for Wound Healing 337\u003c\/p\u003e \u003cp\u003e15.1.1 Definition of Biomaterials 337\u003c\/p\u003e \u003cp\u003e15.1.2 Functional Requirements of Wound Repair Biomaterials 338\u003c\/p\u003e \u003cp\u003e15.1.3 Classification of Biomaterials Commonly Used in Wound Healing 338\u003c\/p\u003e \u003cp\u003e15.2 Synthetic Biomaterials for Wound Healing 339\u003c\/p\u003e \u003cp\u003e15.2.1 Polyurethanes and their Derivatives 340\u003c\/p\u003e \u003cp\u003e15.2.2 Poly l-Lactic Acid 340\u003c\/p\u003e \u003cp\u003e15.2.3 Poly(Ethylene Glycol) 341\u003c\/p\u003e \u003cp\u003e15.2.4 Polycaprolactone 341\u003c\/p\u003e \u003cp\u003e15.2.5 Poly(Glycolic Acid) and Poly(Lactic-co-Glycolic Acid) 342\u003c\/p\u003e \u003cp\u003e15.3 Natural Biomaterials for Wound Healing 343\u003c\/p\u003e \u003cp\u003e15.3.1 Polysaccharide-Based Biomaterials 343\u003c\/p\u003e \u003cp\u003e15.3.2 Protein-Based Biomaterials 348\u003c\/p\u003e \u003cp\u003e15.4 Application of Biomaterials in Wound Healing 350\u003c\/p\u003e \u003cp\u003e15.4.1 Traditional and Impregnated Dressings 350\u003c\/p\u003e \u003cp\u003e15.4.2 Hydrogels 352\u003c\/p\u003e \u003cp\u003e15.4.3 Film Dressings 353\u003c\/p\u003e \u003cp\u003e15.4.4 Foam Dressings 354\u003c\/p\u003e \u003cp\u003e15.4.5 Nanofiber-Based Dressings 355\u003c\/p\u003e \u003cp\u003e15.4.6 Three-Dimensional Printed Dressings 356\u003c\/p\u003e \u003cp\u003e15.5 New Trends in Biomaterials for Wound Healing 357\u003c\/p\u003e \u003cp\u003e15.5.1 Extracellular Matrix-Derived Biomaterials 357\u003c\/p\u003e \u003cp\u003e15.5.2 Tissue Engineered Skin Substitutes 357\u003c\/p\u003e \u003cp\u003e15.6 Conclusions and Future Perspectives 358\u003c\/p\u003e \u003cp\u003eReferences 359\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Wound Dressings and Pressure Ulcers 367\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMichael Clark\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16.1 Overview 367\u003c\/p\u003e \u003cp\u003e16.2 Introduction to Pressure Ulcers 367\u003c\/p\u003e \u003cp\u003e16.3 The Impact of Pressure Ulcers 369\u003c\/p\u003e \u003cp\u003e16.4 Managing Pressure Ulcers 370\u003c\/p\u003e \u003cp\u003e16.5 Wound Dressings in Pressure Ulcer Treatment 371\u003c\/p\u003e \u003cp\u003e16.6 Pressure Ulcer Prevention and Wound Dressings 377\u003c\/p\u003e \u003cp\u003e16.6.1 Pressure Ulcers at the Nose 378\u003c\/p\u003e \u003cp\u003e16.6.2 Pressure Ulcers at the Heel 378\u003c\/p\u003e \u003cp\u003e16.6.3 Pressure Ulcers at the Sacrum 378\u003c\/p\u003e \u003cp\u003e16.7 Conclusions 380\u003c\/p\u003e \u003cp\u003eReferences 380\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 3D Printed Scaffolds for Wound Healing and Tissue Regeneration 385\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAtabak Ghanizadeh Tabriz, Dennis Douroumis and Joshua Boateng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17.1 Introduction 385\u003c\/p\u003e \u003cp\u003e17.2 3D Printing 386\u003c\/p\u003e \u003cp\u003e17.3 Laser-Based Bioprinting 387\u003c\/p\u003e \u003cp\u003e17.4 Jet-Based Printing 389\u003c\/p\u003e \u003cp\u003e17.5 Extrusion-Based Printing 391\u003c\/p\u003e \u003cp\u003e17.6 Hybrid Printing 393\u003c\/p\u003e \u003cp\u003e17.7 Conclusions 395\u003c\/p\u003e \u003cp\u003eReferences 395\u003c\/p\u003e \u003cp\u003eIndex 399\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49528855167319,"sku":"9781119433262","price":145.3,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119433262.jpg?v=1731873288","url":"https:\/\/bookcurl.com\/products\/therapeutic-dressings-and-wound-healing-applications-9781119433262","provider":"Book Curl","version":"1.0","type":"link"}