{"product_id":"the-vestibular-system-9780195167085","title":"The Vestibular System","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe Vestibular System is an integrative look at the vestibular system and the neurobiology of balance.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003eCompelling and timely, this book offers a comprehensive and authoritative survey of current vestibular science... an outstanding reference that will likely find its way into the offices of basic scientists and clinicians alike... The authors have done a wonderful job of consolidating a broad body of current knowledge into a readable book. I highly recommend this to anyone seeking to refine their knowledge of the vestibular system. * Doody's Notes, June 2013 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eI. Introduction ; Chapter 1- The Vestibular System in Everyday Life ; 1.1  Overview of the vestibular system ; 1.2   Visual acuity and the vestibulo-ocular reflex ; 1.3   Air-righting reflex in the cat ; 1.4   Post-rotational reactions ; 1.5   Positional alcohol nystagmus (PAN) ; 1.6   Motion sickness ; 1.7   Vection illusions ; 1.8   The subjective visual vertical ; 1.9   Adaptive plasticity ; 1.10 Path finding and spatial orientation ; 1.11 Postural control ; 1.12 Summary ; 1.13 Selected readings ; II. Peripheral Vestibular System ; Chapter 2 - Structure of the Vestibular Labyrinth ; 2.1 Gross and microscopic anatomy ; 2.2 Fine structure of the sensory regions ; Hair cells ; Supporting cells ; Transitional regions ; 2.3 Regional variations in cellular architecture and afferent innervation ; Cristae ampullares ; Utricular macula ; Saccular macula ; 2.4 Efferent innervation ; 2.5 Summary ; 2.6 Selected readings ; Chapter 3- Hair Cell Transduction ; 3.1 Mechanoelectric transduction ; 3.2 Basolateral currents ; 3.3 Neurotransmitter release and presynaptic calcium ; channels  ; Calcium channels  ; Neurotransmitter release.  ; 3.4 Postsynaptic mechanisms  ; 3.5 Synaptic transmission involving type I hair cells  ; 3.6 Spike encoding  ; 3.7 Efferent neurotransmission  ; 3.8 Summary  ; 3.9 Selected readings  ; Chapter 4- Physiology of the Vestibular Organs  ; 4.1 General features of the vestibular organs  ; Vestibular organs are inertial sensors  ; Resting discharge  ; Discharge regularity  ; Information transmission  ; 4.2 Semicircular canals   ; Directional properties  ; Macromechanics and the torsion-pendulum model  ; Interspecies variations and canal dimensions  ; Afferent response dynamics  ; Variations in gain and phase  ; Afferent morphology and physiology  ; Dynamic range of afferent discharge  ; 4.3 Otolith organs  ; Directional properties  ; Macromechanics and the otoconial membrane  ; Afferent response dynamics  ; Dynamic range of afferent discharge  ; Variations in gain and phase  ; Afferent morphology and physiology  ; 4.4 Summary  ; 4.5 Selected readings  ; Chapter 5-  The Efferent Vestibular System  ; 5.1 Comparative anatomy of central efferent pathways  ; 5.2 Responses of afferents to electrical stimulation of ; EVS  ;  Mammals.  ;  Non-mammals  ; 5.3 Responses of efferents to natural stimulation  ; 5.4 Efferent-mediated responses of afferents  ; 5.5 Possible functions of efferents in mammals  ; 5.6 Summary  ; III. Central Vestibular System  ; Chapter 6 - Neuroanatomy of Central Vestibular Pathways  ; 6.1 Introduction  ; 6.2 The vestibular nuclei: subdivisions and anatomical ; organization  ; Medial vestibular nucleus (MVN)  ; Lateral vestibular nucleus (LVN)  ; Superior vestibular nucleus (SVN)  ; Descending vestibular nucleus (DVN)  ; y group  ; Interstitial nucleus of the vestibular nerve (INT8)  ; Associated cell groups (z, x, f, l,m)  ; Projection and intrinsic neurons  ; Connections with the ipsilateral vestibular nerve  ; Commissural pathways  ; 6.3 Vestibulo-ocular and optokinetic systems  ; Semicircular canal projections to oculomotor neurons  ; Otolith projections to oculomotor neurons  ; Nucleus prepositus hypoglossi (NPH)  ; Interstitial nucleus of Cajal (INC)  ; Reticular formation  ; Optokinetic pathways  ; 6.4 Vestibulospinal systems  ; Medial vestibulospinal tract (MVST)  ; Lateral vestibulospinal tract (LVST)  ; Vestibulo-ocular cervical pathways (VOC)  ; Other vestibulospinal tracts  ; Spinal projections to the vestibular nuclei  ; 6.5 Vestibulocerebellar relations  ; Basic circuitry  ; Vestibular projections to the cerebellum  ; Prepositus nucleus  ; Projections from the deep cerebellar nuclei to the ; vestibular nuclei  ; Projections from the cerebellar cortex to the vestibular ; nuclei  ; Cerebellar cortical modules  ; Lateral reticular nucleus  ; Vestibulo-paramedian tract projections  ; 6.6 Vestibulo-autonomic connections  ; 6.7 Vestibular connections with the neocortex  ; 6.8 Pathways involving the hippocampal formation  ; 6.9 Summary  ; 6.10 Selected readings  ; 6.11 List of abbreviations  ; Chapter 7 -Synaptic Mechanisms in the Vestibular Nuclei  ; 7.1 Historical perspective  ; 7.2 Basic circuitry of the vestibular nuclei  ; Ipsilateral vestibular nerve inputs  ; Commissural connections  ; 7.3 Neurotransmitters in the vestibular nuclei  ; Transmission between the vestibular nerve and secondary ; neurons  ; Transmission within the vestibular nucleus  ; Output pathways of the vestibular nuclei  ; 7.4 Properties of individual neurons  ; Resting discharge  ; 7.5 Central projections of regular and irregular afferents  ; Electrophysiological studies  ; Functional ablation of irregular afferents  ; 7.6 Convergence from separate vestibular organs  ; Convergence from separate vestibular organs  ; Canal-canal convergence  ; Otolith-otolith convergence  ; Spatio-temporal convergence  ; Canal-otolith convergence  ; Convergence from somatosensory receptors  ; 7.7 Summary  ; 7.8 Selected readings  ; IV. Vestibulo-ocular and Vestibulopinal Mechanisms  ; Chapter 8 - An Oculomotor Tutorial  ; 8.1 Overview and classification of eye movement types  ; 8.2 Ocular structure and functional implications  ; The extraocular eye muscles.  ; Mechanics of the oculomotor plant  ; Oculomotor motoneuron discharge.  ; Plant mechanics and premotor control.  ; 8.3 Gaze Redirection  ; Saccades  ; Smooth pursuit  ; Vergence  ; 8.4 Gaze Stabilization  ; Vestibulo-ocular reflexes.  ; Optokinetic system.  ; 8. 5 Interactions between eye and head movements  ; 8.6 Summary  ; 8.7 Selected readings  ; Chapter 9 -Vestibulo-ocular Reflexes  ; 9.1.  Semicircular-canal related angular VOR (AVOR)  ; General properties of the canal-related AVOR.  ; AVOR during high frequency rotations.  ; AVOR at low frequencies - velocity storage.  ; AVOR-visual interactions: the optokinetic system.  ; AVOR in three-dimensions.  ; 9.2. Otolith-ocular reflexes  ; Tilt VOR.  ; Otolith influences on the AVOR during off-vertical axis ; rotations      (OVAR).  ; Otolith influences on the AVOR during canal\/otolith ; conflict.  ; Translational VOR (TVOR).  ; Optic flow during translation.  ; Visual mechanisms for short latency visual compensation ; during translation.  ; Distinguishing tilts from translations.  ; Differences between the AVOR and the TVOR.  ; Functional differences: Foveal rather than full-field image ; stabilization.  ; Dependence on viewing distance and eye position.  ; Response latency and neural pathways.  ; Comparative adaptation  ; 9.3 Summary  ; 9.4 Selected readings  ; Chapter 10-The Vestibulospinal System and Postural Control  ; 10.1. Reflexes versus multisensory strategies  ; 10.2 Multisensory strategies  ; 10.3. Vestibular reflexes: general considerations  ; 10.4  Vestibulocollic reflexes  ; The angular VCR.  ; The linear VCR evoked by translation and tilts.  ; The cervicocollic reflex  ; 10.5. Control systems analysis of the head-neck plant.   ; Head plant.  ; Vestibulocollic reflex.  ; The cervicocollic reflex  ; Reflex interactions.  ; Use of control systems models  ; 10.6. Vestibulospinal and neck reflexes acting on the ; limbs  ; Spatial and temporal properties of the reflexes.  ; Afferent origin of the reflexes  ; Neural substrate of the reflexes.  ; Vestibulospinal actions on hindlimb motoneurons.  ; Vestibulospinal actions on forelimb motoneurons.  ; Tonic neck reflexes.  ; 10.7 Summary  ; 10.8 Selected readings  ; V. Signal Processing in Alert Animals  ; Chapter 11- Signal Processing in Vestibular Nuclei of Alert ; Animals During Natural Behaviors  ; 11.1  Introduction  ; 11.2 Classes of neurons in head-restrained, alert monkeys  ; Position-vestibular-pause (PVP) neurons.  ; Vestibular-only (VO) and vestibular-pause cells.  ; Eye-head (EH) neurons.  ; Burst-tonic (BT) neurons.  ; 11.3 Dynamics of neuronal responses  ; Frequency response during sinusoidal rotations  ; Response linearity  ; Velocity storage  ; 11.4 Response to linear translations in alert ; head-restrained monkeys  ; Distinguishing translational from tilt.  ; 11.5 Interactions with the oculomotor pathways that control ; pursuit eye movements   ; 11.6 Integration of inputs from vestibular and optokinetic ; pathways  ; VN modulation during the OKR   ; Optokinetic pathways to the VN.  ; 11.7 Integration of vestibular and proprioceptive inputs   ; 11.8 Differential processing of active versus passive head ; movements   ; Neuronal responses during active versus passive head ; movement.  ; Mechanisms for the differential processing of ; actively-generated versus passive head movement.  ; 11.9 Vestibular processing depends  on current gaze ; strategy.   ; Vestibular processing during voluntary gaze shifts.  ; Vestibular processing during visual tracking; VOR ; cancellation and eye-head pursuit.  ; Vestibular processing during near versus far viewing.  ; 11.10 Summary  ; 11.11 Selected readings  ; Chapter 12 - The Cerebellum and the Vestibular System  ; 12. 1 Overview of signal processing in the cerebellum  ; The basic cerebellar circuit  ; Vestibular inputs are specific to localized regions of the ; cerebellum  ; 12.2 Nodulus and Ventral Uvula   ; Mossy fiber inputs.  ; Climbing fiber inputs.  ; Efferent connections.  ; Neuronal responses  ; Lesions and function.  ; 12.3 Flocculus and ventral paraflocculus  ; Mossy fiber inputs.  ; Climbing fiber inputs  ; Efferent projections of the flocculus.    ; Differences between the flocculus and ventral ; paraflocculus  ; Neuronal responses.  ; Complex spikes:  ; Simple spikes.  ; Changes in neuronal responses following VOR learning  ; Lesions and function  ; Lesions studies emphasize the role of the flocculus in VOR ; Adaptation and motor learning ; 12.4 The Vermis of the Anterior and Posterior Lobes  ; 12.5 The Deep Cerebellar Nuclei  ; Fastigial Nucleus.  ; Rostral fastigial nucleus  ; Caudal fastigial nucleus  ; The interposed nuclei.  ; Dentate nuclei.  ; 12.6 Summary  ; 12.7 Selected Readings  ; VI..Functional Considerations  ; Chapter 13 - Learning and Compensation in the Vestibular ; System  ; 13.1 Motor learning in the vestibulo-ocular reflex  ; The adaptive capabilities of the VOR.  ; Signal flow in the VOR network.  ; Rules for the VOR and motor learning.  ; Possible sites of motor learning: cerebellum versus brain ; stem  ; Evidence for sites of learning and memory.  ; Possible cellular mechanisms of synaptic plasticity  ; Cerebellar mechanisms  ; Brain stem mechanisms  ; Consolidation of VOR motor memory  ; Generalization: can learning be applied to new situations? ; 13.2. Compensation for vestibular damage  ; Uninilateral labyrinthectomy  ; Activity in the vestibular nuclei following ; labyrinthectomy  ; Cellular mechanisms of compensation in the vestibular ; nuclei  ; The role of the cerebellum in compensation  ; 13.3 Summary  ; 13.4 Selected readings  ; Chapter 14-Cortical Representations of Vestibular ; Information  ; 14.1. Introduction  ; 14.2. Historical Perspective  ; 14.3. Multiple representations of vestibular signals in the ; cerebral cortex.  ; Visuomotor areas in frontal cortex.  ; Extrastriate visual cortex (MSTd).  ; Ventral intraparietal (VIP) area  ; Parieto-insular vestibular cortex (PIVC), area 2v and area ; 3a  ; 14.4. Ascending vestibular pathways through the thalamus  ; 14.5 Descending cortical information affecting vestibular ; responsiveness in the vestibular nuclei  ; 14.6. Vestibular influences in the head direction circuit of ; the limbic system  ; 14.7 Summary  ; 14.8 Selected readings  ; Chapter 15-Reference Frames Used in the Coding Vestibular ; Information  ; 15.1. Definitions of coordinate systems and reference ; frames  ; 15.2. Head- versus body-centered reference frames: ; Vestibular\/neck          proprioceptive interactions  ; 15.3. Head- versus eye-centered reference frames for ; self-motion perception: vestibular\/visual interactions in ; extrastriate visual cortex  ; 15.4. Head- versus world-centered reference frames: ; Canal\/otolith   convergence for inertial motion detection  ; 15.5 Computational solution for the two ambiguities of peripheral ; vestibular sensors  ; The rotation problem: allocentric coding of angular velocity ; The linear acceleration problem: evidence for segregation of ; tilt and translation  ; Tilt-translation exceptions ; VII. Clinical Disorders  ; Chapter 16- Clinical Manifestations of Vestibular ; Dysfunction  ; 16.1 Prevalence and impact of vestibular disorders  ; 16.2 Diagnosis of vestibular disorders  ; 16.3 Planes of individual canals and direction of eye ; movements  ; Benign paroxysmal positional vertigo  ; Positional alcohol nystagmus   ; Superior semicircular canal dehiscence syndrome  ; 16.4 Recovery of the horizontal VOR after unilateral ; labyrinthectomy  ; 16.5 Multisensory control of posture  ; 16.6 Disorders of otolith function  ; 16.7 Clinical tests of vestibular function  ; Caloric test  ; Rotational chair tests  ; Quantitative evaluation of the VOR evoked by rapid head ; movements  ; Vestibular-evoked myogenic potentials (VEMPs)  ; 16.7 Future directions  ; Hair-cell regeneration  ; Vestibular prosthesis  ; 16.8 Summary  ; 16.9 Selected readings","brand":"Oxford University Press, USA","offers":[{"title":"Default Title","offer_id":51766888268119,"sku":"9780195167085","price":185.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780195167085.jpg?v=1758711527","url":"https:\/\/bookcurl.com\/products\/the-vestibular-system-9780195167085","provider":"Book Curl","version":"1.0","type":"link"}