{"product_id":"synthetic-multivalent-molecules-9780471563471","title":"Synthetic Multivalent Molecules","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eProvides basic principles of multivalent interactions found in biological systems as well as coverage in design concepts, syntheses, and biological activities of multivalent molecules. This book contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e“…an excellent compilation of multivalent systems and their biological applications.” (\u003ci\u003eChemBioChem\u003c\/i\u003e, 2005; Vol. 6; 7)  \u003cp\u003e\"This authoritative information reference…will fit into the library collections at research universities, medical schools and (bio) pharmaceutical companies.\" (\u003ci\u003eE-STREAMS\u003c\/i\u003e, March 2005)\u003c\/p\u003e \u003cp\u003e\"…a fine attempt to provide in one volume all of the various aspects of the field, and it presents a wealth of information on topics that are difficult to find elsewhere…\" (\u003ci\u003eJournal of Medicinal Chemistry\u003c\/i\u003e, February 24, 2005)\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface.  \u003cp\u003eNotes for Organization and Classification.\u003c\/p\u003e \u003cp\u003eAbbreviations.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Nomenclature and Definitions.\u003c\/p\u003e \u003cp\u003e1.2 Mechanistic Aspects of Multivalent Interaction.\u003c\/p\u003e \u003cp\u003e1.3 Biological Roles of Multivalent Ligands.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Multivalent Molecules Applied to Viral Targets.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Influenza Virus.\u003c\/p\u003e \u003cp\u003e2.2 Human Immunodeficiency Virus.\u003c\/p\u003e \u003cp\u003e2.3 Rotavirus.\u003c\/p\u003e \u003cp\u003e2.4 Polyoma Virus.\u003c\/p\u003e \u003cp\u003e2.5 Picorna Virus.\u003c\/p\u003e \u003cp\u003e2.6 Respiratory Syncytial Virus.\u003c\/p\u003e \u003cp\u003e2.7 Dengue Virus.\u003c\/p\u003e \u003cp\u003e2.8 Nucleic Acids of Viruses.\u003c\/p\u003e \u003cp\u003e2.9 Synthetic Multivalent Vaccines.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Multivalent Molecules Applied to Bacterial Targets.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Targets in Bacterial Cell Membranes.\u003c\/p\u003e \u003cp\u003e3.2 Bacterial Toxins.\u003c\/p\u003e \u003cp\u003e3.3 Bacterial Enzymes.\u003c\/p\u003e \u003cp\u003e3.4 Bacterial Nucleic Acids.\u003c\/p\u003e \u003cp\u003e3.5 Multivalent Molecules as Synthetic Vaccines.\u003c\/p\u003e \u003cp\u003e3.6 Fungal Cells.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Multivalent Molecules Applied to Cellular Targets.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Carbohydrate-Recognition Receptors on Cell Surfaces.\u003c\/p\u003e \u003cp\u003e4.2 Peptide and Hormone Recognition Receptors on Cell Surfaces.\u003c\/p\u003e \u003cp\u003e4.3 Ligand-Mediated Receptor Dimerization.\u003c\/p\u003e \u003cp\u003e4.4 Enzymes.\u003c\/p\u003e \u003cp\u003e4.5 G-Protein-Coupled Receptors.\u003c\/p\u003e \u003cp\u003e4.6 Ion Channels.\u003c\/p\u003e \u003cp\u003e4.7 Nucleic Acids.\u003c\/p\u003e \u003cp\u003e4.8 Antibodies.\u003c\/p\u003e \u003cp\u003e4.9 Cell Surface Engineering.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Chemical Synthesis of Multivalent Molecules.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Selected Synthetic Methods for Multimerization.\u003c\/p\u003e \u003cp\u003e5.2 Combinatorial Chemistry.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAppendix.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eTable 1. Divalent Ligands Linked to Enzymes in Human Immunodeficiency Virus (HIV).\u003c\/p\u003e \u003cp\u003eTable 2. Multivalent Ligands Linked to gp120 Surface Receptors in Human Immunodeficiency Virus.\u003c\/p\u003e \u003cp\u003eTable 3. Multivalent Ligands Linked to Surface Receptors on Viruses.\u003c\/p\u003e \u003cp\u003eTable 4. Multivalent Receptors Targeting Multivalent Ligands in Bacterial Cell Walls.\u003c\/p\u003e \u003cp\u003eTable 5. Multivalent Ligands Targeting Bacterial Receptors in Membrane Surfaces.\u003c\/p\u003e \u003cp\u003eTable 6. Multivalent Ligands Linked to Bacterial Toxins.\u003c\/p\u003e \u003cp\u003eTable 7. Multivalent Molecules Targeting Bacterial Enzymes.\u003c\/p\u003e \u003cp\u003eTable 8. Multivalent Ligands Targeting Carbohydrate-Recognition Receptors on Cellular Surfaces.\u003c\/p\u003e \u003cp\u003eTable 9. Multivalent Ligands Targeting Noncarbohydrate-Recognition Receptors on Cellular Surfaces.\u003c\/p\u003e \u003cp\u003eTable 10. Multivalent Ligands Linked to Selectins on Cell Surfaces.\u003c\/p\u003e \u003cp\u003eTable 11. Multivalent Ligands Linked to Lectins.\u003c\/p\u003e \u003cp\u003eTable 12. Multivalent Ligands Linked to Cellular Enzymes.\u003c\/p\u003e \u003cp\u003eTable 13. Multivalent Ligands Linked to G-Protein-Coupled Receptors (GPCRs).\u003c\/p\u003e \u003cp\u003eTable 14. Multivalent Ion Channel–Binding Molecules.\u003c\/p\u003e \u003cp\u003eTable 15. Homo- and Heterodivalent Chemical Inducers of Dimerization (CIDs).\u003c\/p\u003e \u003cp\u003eTable 16. Multivalent Ligands Linked to Nucleic Acids.\u003c\/p\u003e \u003cp\u003eTable 17. Synthetic Multivalent Antigens.\u003c\/p\u003e \u003cp\u003eTable 18. Multivalent Ligands Displayed on Self-Assembled Monolayer (SAM) Made of Alkanethiolate on Gold.\u003c\/p\u003e \u003cp\u003eTable 19. (Bio)chemical Modification of Cell Surface Antigens.\u003c\/p\u003e \u003cp\u003eTable 20. Multivalent Targets.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402632110423,"sku":"9780471563471","price":147.56,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780471563471.jpg?v=1730481051","url":"https:\/\/bookcurl.com\/products\/synthetic-multivalent-molecules-9780471563471","provider":"Book Curl","version":"1.0","type":"link"}