{"product_id":"sperm-nuclear-maturation-a-basic-clinical-approach-9781616681944","title":"Sperm Nuclear Maturation: A Basic \u0026 Clinical","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eIn somatic cells, DNA is normally wrapped around the histones octamer to forms nucleosomes that eventually give rise to a solenoid DNA structure. Unlike somatic cells, in mammalian sperm, the development of spermatids into mature spermatozoa is accomplished by a series of structural and chemical modifications including a gradual replacement of lysine-rich histones by transition proteins and then by protamines which bind more tightly to DNA than histones, which results in compaction of chromatin in the sperm nucleus, a process which is termed ''sperm chromatin condensation''. This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa.","brand":"Nova Science Publishers Inc","offers":[{"title":"Default Title","offer_id":48886868803927,"sku":"9781616681944","price":39.74,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/sperm-nuclear-maturation-a-basic-clinical-approach-9781616681944","provider":"Book Curl","version":"1.0","type":"link"}