{"product_id":"singer-and-monaghans-cervical-and-lower-genital-tract-precancer-9780470674413","title":"Singer and Monaghans Cervical and Lower Genital","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe guide to effective practice management of precancerous lesions in cervix and lower genital tract.      This third edition contains in-depth examination of the different modalities that contribute to the safe and scientific management of precancerous lesions in the female genital tract.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface to the Third Edition ix\u003c\/p\u003e \u003cp\u003ePreface to the First Edition x\u003c\/p\u003e \u003cp\u003eAcknowledgements xi\u003c\/p\u003e \u003cp\u003e1 The Histopathology of Lower Genital Tract Neoplasia 1\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e1.2 Terminology 1\u003c\/p\u003e \u003cp\u003e1.3 Histopathologic features of cervical intraepithelial neoplasia or squamous intraepithelial lesion 3\u003c\/p\u003e \u003cp\u003e1.4 Cervical glandular intraepithelial neoplasia and adenocarcinoma in situ 6\u003c\/p\u003e \u003cp\u003e1.5 Early invasive carcinoma 7\u003c\/p\u003e \u003cp\u003e1.6 Vaginal intraepithelial neoplasia 11\u003c\/p\u003e \u003cp\u003e1.7 Vulval precancer 11\u003c\/p\u003e \u003cp\u003e1.8 Related topics 12\u003c\/p\u003e \u003cp\u003e1.9 Further reading 13\u003c\/p\u003e \u003cp\u003e2 Human Papillomaviruses in the Pathogenesis of Lower Genital Tract Neoplasia 14\u003c\/p\u003e \u003cp\u003e2.1 Introduction 14\u003c\/p\u003e \u003cp\u003e2.2 Characteristics of human papillomaviruses 14\u003c\/p\u003e \u003cp\u003e2.3 Manifestations of genital human papillomavirus infections 15\u003c\/p\u003e \u003cp\u003e2.4 Prevalence of genital human papillomavirus infections 18\u003c\/p\u003e \u003cp\u003e2.5 Transmission of genital human papillomavirus infections 19\u003c\/p\u003e \u003cp\u003e2.6 Risk factors for genital human papillomavirus infections 19\u003c\/p\u003e \u003cp\u003e2.7 Natural history of cervical human papillomavirus infections 19\u003c\/p\u003e \u003cp\u003e2.8 Molecular pathways of human papillomavirus oncogenesis 19\u003c\/p\u003e \u003cp\u003e2.9 The effect of human papillomavirus\/host cell interaction: a prerequisite for neoplasia 21\u003c\/p\u003e \u003cp\u003e2.10 The role of oncogenic human papillomavirus detection in the prevention of lower genital tract precancer 22\u003c\/p\u003e \u003cp\u003e2.11 Further reading 23\u003c\/p\u003e \u003cp\u003e3 Examination for Cervical Precancer: Use of colposcopy 24\u003c\/p\u003e \u003cp\u003e3.1 Introduction 24\u003c\/p\u003e \u003cp\u003e3.2 Tissue basis for colposcopy 24\u003c\/p\u003e \u003cp\u003e3.3 The colposcopic examination 25\u003c\/p\u003e \u003cp\u003e3.4 Video colposcopy 31\u003c\/p\u003e \u003cp\u003e3.5 Image and electronic data management 31\u003c\/p\u003e \u003cp\u003e3.6 Further reading 32\u003c\/p\u003e \u003cp\u003e4 Colposcopy of the Normal Cervix: A prerequisite to establishing the diagnosis of cervical precancer 33\u003c\/p\u003e \u003cp\u003e4.1 Introduction 33\u003c\/p\u003e \u003cp\u003e4.2 Cervical epithelium: natural history 33\u003c\/p\u003e \u003cp\u003e4.3 Cervical epithelium: topography 34\u003c\/p\u003e \u003cp\u003e4.4 Cervical epithelium: colposcopic appearances 35\u003c\/p\u003e \u003cp\u003e4.5 Squamous metaplastic epithelium 38\u003c\/p\u003e \u003cp\u003e4.6 Colposcopy of the adolescent cervix 44\u003c\/p\u003e \u003cp\u003e4.7 Cervical epithelium during pregnancy and puerperium 46\u003c\/p\u003e \u003cp\u003e4.8 The effect of vaginal delivery on the cervical epithelium 48\u003c\/p\u003e \u003cp\u003e4.9 The cervical epithelium during the menopause 50\u003c\/p\u003e \u003cp\u003e4.10 The oral contraceptives and their effect on the cervix 52\u003c\/p\u003e \u003cp\u003e4.11 The congenital transformation zone 53\u003c\/p\u003e \u003cp\u003e4.12 Further reading 58\u003c\/p\u003e \u003cp\u003e5 Cytology and Screening for Cervical Precancer 59\u003c\/p\u003e \u003cp\u003e5.1 Introduction 59\u003c\/p\u003e \u003cp\u003e5.2 Cytologic classifications 59\u003c\/p\u003e \u003cp\u003e5.3 Cytologic reporting 60\u003c\/p\u003e \u003cp\u003e5.4 Clinical referral 63\u003c\/p\u003e \u003cp\u003e5.5 Cytodiagnosis of cervical glandular intraepithelial neoplasia\/adenocarcinoma in situ 66\u003c\/p\u003e \u003cp\u003e5.6 Cytologic features of adenocarcinoma 68\u003c\/p\u003e \u003cp\u003e5.7 Screening for cervical cancer 68\u003c\/p\u003e \u003cp\u003e5.8 Improvements to cervical screening 70\u003c\/p\u003e \u003cp\u003e5.9 Cytologic interpretation 72\u003c\/p\u003e \u003cp\u003e5.10 Role of human papillomavirus testing in the UK NHS Cervical Screening Programme 72\u003c\/p\u003e \u003cp\u003e5.11 Primary screening with human papillomavirus testing 73\u003c\/p\u003e \u003cp\u003e5.12 Human papillomavirus test as follow-up after treatment of cervical intraepithelial neoplasia 74\u003c\/p\u003e \u003cp\u003e5.13 Human papillomavirus testing to triage minor cytologic lesions 74\u003c\/p\u003e \u003cp\u003e5.14 Role of type-specific human papillomavirus tests 74\u003c\/p\u003e \u003cp\u003e5.15 Further reading 75\u003c\/p\u003e \u003cp\u003e6 Diagnosis of Cervical Precancer: Use of colposcopy 76\u003c\/p\u003e \u003cp\u003e6.1 Introduction 76\u003c\/p\u003e \u003cp\u003e6.2 Which cytologic abnormalities need further investigation? 76\u003c\/p\u003e \u003cp\u003e6.3 Colposcopy: the initial clinical examination 76\u003c\/p\u003e \u003cp\u003e6.4 The rationale for the use of colposcopy in the diagnosis of cervical precancer 77\u003c\/p\u003e \u003cp\u003e6.5 Colposcopic appearance of the abnormal (atypical) cervical epithelium 78\u003c\/p\u003e \u003cp\u003e6.6 The classification of colposcopically abnormal (atypical) cervical epithelium 87\u003c\/p\u003e \u003cp\u003e6.7 Colposcopic examination of the precancerous\/cancerous cervix 88\u003c\/p\u003e \u003cp\u003e6.8 Benign condyloma of cervix 104\u003c\/p\u003e \u003cp\u003e6.9 Correlation of diagnostic methods in the detection of cervical squamous precancer 111\u003c\/p\u003e \u003cp\u003e6.10 Lack of correlation between diagnostic methods 116\u003c\/p\u003e \u003cp\u003e6.11 The diagnosis of early invasion 117\u003c\/p\u003e \u003cp\u003e6.12 Preclinical invasive carcinoma (colposcopically overt\/suspect): colposcopy and pathology 122\u003c\/p\u003e \u003cp\u003e6.13 Precancerous glandular lesions of the cervix 125\u003c\/p\u003e \u003cp\u003e6.14 Colposcopic diagnosis of early adenocarcinoma of the cervix 128\u003c\/p\u003e \u003cp\u003e6.15 Further reading 135\u003c\/p\u003e \u003cp\u003e7 Management of Cervical Precancer 136\u003c\/p\u003e \u003cp\u003e7.1 Introduction 136\u003c\/p\u003e \u003cp\u003e7.2 Rationale behind treatment 136\u003c\/p\u003e \u003cp\u003e7.3 Colposcopic and pathologic characteristics of cervical intraepithelial neoplasia lesions: a prerequisite to treatment 136\u003c\/p\u003e \u003cp\u003e7.4 Colposcopically directed biopsy 139\u003c\/p\u003e \u003cp\u003e7.5 How to manage abnormal cytology? 140\u003c\/p\u003e \u003cp\u003e7.6 Which lesions to treat 143\u003c\/p\u003e \u003cp\u003e7.7 Prerequisites for treatment 144\u003c\/p\u003e \u003cp\u003e7.8 Methods of treatment 145\u003c\/p\u003e \u003cp\u003e7.9 Excision techniques for treating cervical intraepithelial neoplasia 153\u003c\/p\u003e \u003cp\u003e7.10 Management of extension of the abnormal (atypical) transformation zone 163\u003c\/p\u003e \u003cp\u003e7.11 Hysterectomy in the treatment of cervical intraepithelial neoplasia 166\u003c\/p\u003e \u003cp\u003e7.12 Immediate complications of cervical intraepithelial neoplasia treatment 166\u003c\/p\u003e \u003cp\u003e7.13 Long-term complications of cervical intraepithelial neoplasia treatment 168\u003c\/p\u003e \u003cp\u003e7.14 Follow-up after treatment of cervical intraepithelial neoplasia 171\u003c\/p\u003e \u003cp\u003e7.15 Treatment of suspected recurrence 174\u003c\/p\u003e \u003cp\u003e7.16 Precancer in pregnancy 174\u003c\/p\u003e \u003cp\u003e7.17 Precancer in the HIV-positive patient 178\u003c\/p\u003e \u003cp\u003e7.18 Management of early invasive squamous carcinoma of the cervix (FIGO stage I) 180\u003c\/p\u003e \u003cp\u003e7.19 Further reading 184\u003c\/p\u003e \u003cp\u003e8 Vaginal Intraepithelial Neoplasia 185\u003c\/p\u003e \u003cp\u003e8.1 Introduction 185\u003c\/p\u003e \u003cp\u003e8.2 Natural history of vaginal intraepithelial neoplasia 185\u003c\/p\u003e \u003cp\u003e8.3 Etiology 186\u003c\/p\u003e \u003cp\u003e8.4 Clinical presentation 186\u003c\/p\u003e \u003cp\u003e8.5 Vaginal intraepithelial neoplasia following hysterectomy 189\u003c\/p\u003e \u003cp\u003e8.6 Biopsy of the vaginal intraepithelial neoplasia lesion 191\u003c\/p\u003e \u003cp\u003e8.7 Pathology of vaginal intraepithelial neoplasia: is it a precancerous lesion? 193\u003c\/p\u003e \u003cp\u003e8.8 Vaginal precancer and cancer: part of the lower genital tract neoplastic syndrome 194\u003c\/p\u003e \u003cp\u003e8.9 Treatment of vaginal intraepithelial neoplasia 199\u003c\/p\u003e \u003cp\u003e8.10 Further reading 204\u003c\/p\u003e \u003cp\u003e9 Vulval Intraepithelial Neoplasia 205\u003c\/p\u003e \u003cp\u003e9.1 Introduction 205\u003c\/p\u003e \u003cp\u003e9.2 Epidemiology and pathogenesis 205\u003c\/p\u003e \u003cp\u003e9.3 Natural history of vulval intraepithelial neoplasia: the rationale for treatment? 207\u003c\/p\u003e \u003cp\u003e9.4 Pathology 209\u003c\/p\u003e \u003cp\u003e9.5 The clinical examination in general 211\u003c\/p\u003e \u003cp\u003e9.6 The clinical examination (specific) 215\u003c\/p\u003e \u003cp\u003e9.7 Vulval intraepithelial neoplasia affecting the pilosebaceous unit 222\u003c\/p\u003e \u003cp\u003e9.8 Superficially invasive carcinoma of the vulva 223\u003c\/p\u003e \u003cp\u003e9.9 Lichen sclerosus 228\u003c\/p\u003e \u003cp\u003e9.10 Paget’s disease (non-squamous intraepithelial neoplasia) 230\u003c\/p\u003e \u003cp\u003e9.11 Vulval lesions masquerading as cancer or precancer 231\u003c\/p\u003e \u003cp\u003e9.12 Skin and accessory appendages that are important for the management of vulval intraepithelial neoplasia 237\u003c\/p\u003e \u003cp\u003e9.13 Management of vulval intraepithelial neoplasia 239\u003c\/p\u003e \u003cp\u003e9.14 Treatment of superficial invasive vulval carcinoma 254\u003c\/p\u003e \u003cp\u003e9.15 Further reading 255\u003c\/p\u003e \u003cp\u003e10 Perianal and Anal Intraepithelial Neoplasia 256\u003c\/p\u003e \u003cp\u003e10.1 Epidemiology 256\u003c\/p\u003e \u003cp\u003e10.2 Etiology 256\u003c\/p\u003e \u003cp\u003e10.3 Association with other genital intraepithelial neoplastic diseases 257\u003c\/p\u003e \u003cp\u003e10.4 Examination 257\u003c\/p\u003e \u003cp\u003e10.5 Presentation 258\u003c\/p\u003e \u003cp\u003e10.6 Lesions masquerading as intraepithelial neoplasia 260\u003c\/p\u003e \u003cp\u003e10.7 Anal canal involvement 261\u003c\/p\u003e \u003cp\u003e10.8 Management and treatment 262\u003c\/p\u003e \u003cp\u003e10.9 Further reading 267\u003c\/p\u003e \u003cp\u003e11 Genital Tract Adenosis 268\u003c\/p\u003e \u003cp\u003e11.1 Introduction 268\u003c\/p\u003e \u003cp\u003e11.2 Developmental anatomy 268\u003c\/p\u003e \u003cp\u003e11.3 Developmental anomalies caused by diethylstilbestrol 269\u003c\/p\u003e \u003cp\u003e11.4 Present situation 272\u003c\/p\u003e \u003cp\u003e11.5 Further reading 272\u003c\/p\u003e \u003cp\u003e12 Infective and Other Conditions Causing Confusion in Diagnosis of Lower Genital Tract Precancer 273\u003c\/p\u003e \u003cp\u003e12.1 Introduction 273\u003c\/p\u003e \u003cp\u003e12.2 Trichomonas vaginalis 273\u003c\/p\u003e \u003cp\u003e12.3 Bacterial vaginosis 273\u003c\/p\u003e \u003cp\u003e12.4 Candidiasis 274\u003c\/p\u003e \u003cp\u003e12.5 Herpes genitalis infection 275\u003c\/p\u003e \u003cp\u003e12.6 Human papillomavirus infection 279\u003c\/p\u003e \u003cp\u003e12.7 Cervical deciduosis in pregnancy 280\u003c\/p\u003e \u003cp\u003e12.8 Polypoid lesions of the cervix 282\u003c\/p\u003e \u003cp\u003e12.9 Further reading 285\u003c\/p\u003e \u003cp\u003eIndex 287\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default 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