{"product_id":"rna-therapeutics-9781071647417","title":"RNA Therapeutics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp class=\"MsoListParagraphCxSpMiddle\" style=\"mso-add-space: auto; text-indent: -.25in; line-height: normal; mso-list: l0 level1 lfo1; margin: 0in 0in 0in 46.4pt;\"\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eRNA therapeutics: Bridging discovery and clinical implementation.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eMolecular mechanisms of innate immune sensing of exogenous RNAs.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eChemical modifications in nucleic acid therapeutic.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eEffects of nucleoside modifications on mRNA Translation: Choosing the right modifications.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\" style=\"mso-bidi-font-family: 'Times New Roman';\"\u003eGeneration of lipid nanoparticle mRNA vaccines and evaluation of antigen specific CD8\u003csup\u003e+\u003c\/sup\u003e T cell responses.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eAssessing the immunogenicity of synthetic RNA using blood cells.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eLateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eHydrophobic chromatography purification of linearized Plasmid DNA reduces dsRNA formation during in vitro transcription.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong style=\"mso-bidi-font-weight: normal;\"\u003e\u003cspan lang=\"EN-GB\" style=\"mso-bidi-font-family: 'Times New Roman';\"\u003eOptimization of \u003cem\u003eIn vitro\u003c\/em\u003e transcription reaction for mRNA production using chromatographic at-line monitoring.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eLarge scale production of unmodified mRNA for reprogramming human dendritic cells and T cells.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eProduction of mRNA-loaded dendritic cell cancer vaccines.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eEnhancing cancer vaccine efficacy: siRNA-based modulation of immune suppressive factors in dendritic cells.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003emRNA-based engineering of viral antigen-specific TCR-T cells.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eEngineering mRNA CAR-T cells for cancer immunotherapy.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eGenerating mRNA encoding anti-HBV designer epigenome modifiers.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eLipid nanoparticles for the delivery of mRN.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eOptimization of DOTAP\/cholesterol cationic lipid nanoparticles for nucleic acid delivery.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eFormulation and characterization of cationic bicelles for siRNA delivery.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eBioinspired extracellular vesicles for enhanced delivery of siRNA to tumours.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\" style=\"color: black; mso-themecolor: text1; mso-fareast-language: KO;\"\u003eConstruction of nanotube-shaped mRNA vehicles using self-assembling peptides.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eNanoparticle-mediated siRNA delivery in human epithelial lung cells cultured at the air-liquid interface.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eDeveloping aptamer-targeted mRNA for immunotherapy.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eA facile method for assessing cellular stability and co-localization of Cas9 mRNA and sgRNA using confocal microscopy.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003esiRMSD: A structural parameter to reduce sequence-dependent off-target effects for siRNA design with chemical modifications.- \u003c\/span\u003e\u003c\/strong\u003e\u003c!--[endif]--\u003e\u003cstrong\u003e\u003cspan lang=\"EN-GB\"\u003eChemical strategies to enhance antisense strand selection and minimize off-target effect-mediated by siRNAs.- \u003c\/span\u003e\u003c\/strong\u003e\u003cstrong style=\"mso-bidi-font-weight: normal;\"\u003e\u003cem\u003e\u003cspan style=\"mso-bidi-font-family: 'Times New Roman'; mso-ansi-language: EN-US;\"\u003eIn vivo\u003c\/span\u003e\u003c\/em\u003e\u003c\/strong\u003e\u003cstrong style=\"mso-bidi-font-weight: normal;\"\u003e\u003cspan style=\"mso-bidi-font-family: 'Times New Roman'; mso-ansi-language: EN-US;\"\u003e fermentation production of RNA interference agents.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Humana","offers":[{"title":"Default Title","offer_id":53186416836951,"sku":"9781071647417","price":151.99,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/rna-therapeutics-9781071647417","provider":"Book Curl","version":"1.0","type":"link"}