{"product_id":"ribosome-biogenesis-9781071625002","title":"Ribosome Biogenesis","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cdiv\u003eThis Open Access volume provides comprehensive reviews and describes the latest techniques to study eukaryotic ribosome biogenesis. For more than 50 years ribosomes are a major research topic. Our knowledge about ribosome biogenesis and function such as   transcription, mRNA modification, and translation was the sine qua non for developing the powerful RNA-based vaccines against RNA-viruses causing the world-threatening Covid-19 pandemia. The chapters in this book are organized into six parts. Part One discusses a comparative survey about the unity and diversity of ribosome biogenesis in pro- and eukaryotic cells. Part Two deals with the genomic organization of eukaryotic rDNA and the role of RNA polymerase I in ribosomal RNA transcription. Part Three explores in vitro methods to study RNA polymerase I structure and its function, and Part Four analyzes the nucleo-cytoplasmic transport of assembled ribosomes and RNP complexes. Part Five covers modifications that increase \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eDedication……\u003cbr\u003eAcknowledgments…\u003cbr\u003ePreface…\u003cbr\u003eTable of Contents…\u003cbr\u003eContributing Authors…\u003cbr\u003e\u003cbr\u003ePart I Ribosome Biogenesis\u003cbr\u003e\u003cbr\u003e1.\tA Comparative Perspective on Ribosome Biogenesis: Unity and Diversity across the Tree of Life\u003cbr\u003eMichael Jüttner and Sébastien Ferreira-Cerca\u003cbr\u003e\u003cbr\u003ePart II Genomic Organization\u003cbr\u003e\u003cbr\u003e2.\tEstablishment and Maintenance of Open Ribosomal RNA Gene Chromatin States in Eukaryotes\u003cbr\u003eChristopher Schächner, Philipp E. Merkl, Michael Pilsl, Katrin Schwank, Kristin Hergert, Sebastian Kruse, Philipp Milkereit, Herbert Tschochner, and Joachim Griesenbeck\u003cbr\u003e\u003cbr\u003e3.\tAnalysis of Yeast RNAP I Transcription of Nucleosomal Templates In Vitro\u003cbr\u003ePhilipp E. Merkl, Christopher Schächner, Michael Pilsl, Katrin Schwank, Kristin Hergert, Gernot Längst, Philipp Milkereit, Joachim Griesenbeck, and Herbert Tschochner\u003cbr\u003e\u003cbr\u003ePart III RNA Polymerases\u003cbr\u003e\u003cbr\u003e4.\tSpecialization of RNA Polymerase I in Comparison to Other Nuclear RNA Polymerases of Saccharomyces cerevisiae\u003cbr\u003ePhilipp E. Merkl, Christopher Schächner, Michael Pilsl, Katrin Schwank, Catharina Schmid, Gernot Längst, Philipp Milkereit, Joachim Griesenbeck, and Herbert Tschochner\u003cbr\u003e\u003cbr\u003e5.\tStructural Studies of Eukaryotic RNA Polymerase I using Cryo-Electron Microscopy\u003cbr\u003eMichael Pilsl and Christoph Engel\u003cbr\u003e\u003cbr\u003e6.\tPreparation of RNA Polymerase Complexes for their Analysis by Single Particle Cryo-Electron Microscopy\u003cbr\u003eMichael Pilsl, Florian B. Heiss, Gisela Pöll, Mona Höcherl, Philipp Milkereit, and Christoph Engel\u003cbr\u003e\u003cbr\u003ePart IV Ribosome Assembly, Transport and RNP Complexes\u003cbr\u003e\u003cbr\u003e7.\tEukaryotic Ribosome Assembly and Nucleo-Cytoplasmic Transport\u003cbr\u003eMichaela Oborská-Oplová, Ute Fischer, Martin Altvater, and Vikram Govind Panse\u003cbr\u003e\u003cbr\u003e8.\tTethered MNase Structure Probing as Versatile Technique for Analyzing RNPs using Tagging Cassettes for Homologous Recombination in Saccharomyces cerevisiae \u003cbr\u003eFabian Teubl, Katrin Schwank, Uli Ohmayer, Joachim Griesenbeck, Herbert Tschochner, and Philipp Milkereit\u003cbr\u003e\u003cbr\u003ePart V RNA Modification\u003cbr\u003e\u003cbr\u003e9.\tChemical Modifications of Ribosomal RNA\u003cbr\u003eSunny Sharma and Karl-Dieter Entian\u003cbr\u003e\u003cbr\u003e10.\tIn Vitro Selection of Deoxyribozymes for the Detection of RNA Modifications\u003cbr\u003eAnam Liaqat, Maksim V. Sednev, and Claudia Höbartner\u003cbr\u003e\u003cbr\u003e11.\tMapping of the Chemical Modifications of rRNAs \u003cbr\u003eJun Yang, Peter Watzinger, and Sunny Sharma\u003cbr\u003e\u003cbr\u003e12.\tNon-Radioactive In Vivo Labelling of RNA with 4-thio-uracil\u003cbr\u003eChristina Braun, Robert Knüppel, Jorge Perez-Fernandez, and Sébastien Ferreira-Cerca\u003cbr\u003e\u003cbr\u003ePart VI Translation\u003cbr\u003e\u003cbr\u003e13.\tTranslation Phases in Eukaryotes\u003cbr\u003eSandra Blanchet and Namit Ranjan\u003cbr\u003e\u003cbr\u003e14.\tDifferential Translation Activity using Bio-Orthogonal Non-Canonical Amino Acids Tagging (BONCAT) in Archaea\u003cbr\u003eMichael Kern and Sébastien Ferreira-Cerca\u003cbr\u003e\u003cbr\u003e15.\tThermofluor-Based Analysis of Protein Integrity and Ligand Interactions \u003cbr\u003eSophia Pinz, Eva Doskocil, and Wolfgang Seufert\u003cbr\u003e\u003cbr\u003e16.\tIn Vitro Assembly of a Fully Reconstituted Yeast Translation System for Studies of Initiation and Elongation Phases of Protein Synthesis\u003cbr\u003eSandra Blancher and Namit Ranjan\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Springer-Verlag New York Inc.","offers":[{"title":"Default Title","offer_id":51039240585559,"sku":"9781071625002","price":999.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781071625002.jpg?v=1750943024","url":"https:\/\/bookcurl.com\/products\/ribosome-biogenesis-9781071625002","provider":"Book Curl","version":"1.0","type":"link"}