{"product_id":"regulation-of-g-protein-coupled-receptor-function-and-expression-9780471252771","title":"Regulation of G Protein Coupled Receptor Function","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eRecent advances in molecular and cell biology enabling the cloning, expression, and mutagenesis of signal transduction proteins has prompted an explosion of knowledge in the field of receptor regulation, facilitating the discovery of new classes of regulatory proteins, and providing a basis and means for manipulating receptor function through multiple intracellular targets.\u003cbr\u003e \u003cbr\u003e This volume covers methods used to examine how the function(s) of receptors are regulated. Understanding how to regulate the function and expression of these receptors is critical in determining how to modify receptors and to translocating receptors away from the cell surface and its recycling.\u003cbr\u003e \u003cbr\u003e Individual chapters focus on specific techniques used to characterize receptors (epitope tagging, measurement and analysis of receptor phosphorylation, analysis of the kinetics of receptor desensitization, and assessment of receptor\/G protein coupling); the role of regulatory proteins (receptor kinases and p\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eTECHNIQUES FOR CHARACTERIZING RECEPTOR FUNCTION.\u003cbr\u003e \u003cbr\u003e Epitope Tagging and Detection Methods for Receptor Identification (U. Klein \u0026amp; M. von Zastrow).\u003cbr\u003e \u003cbr\u003e Measurement of Receptor Phosphorylation in Situ (M. Bouvier, et al.).\u003cbr\u003e \u003cbr\u003e Reconstitution and in vitro Phosphorylation of G Protein-Coupled Receptors (J. Ptasienski \u0026amp; M. Hosey).\u003cbr\u003e \u003cbr\u003e Identification of Residues that are Phosphorylated within a Receptor (K. Palczewski, et al.).\u003cbr\u003e \u003cbr\u003e Palmitoylation of G Protein-Coupled Receptors (H. Jin, et al.).\u003cbr\u003e \u003cbr\u003e Assays for Measuring Receptor\/G Protein Coupling (Q. Li \u0026amp; R. Cerione).\u003cbr\u003e \u003cbr\u003e PROTEINS THAT REGULATE RECEPTOR FUNCTION.\u003cbr\u003e \u003cbr\u003e Expression and Activity of G Protein-Coupled Receptor Kinases (R. Loudon, et al.).\u003cbr\u003e \u003cbr\u003e Characterization of Arrestin Expression and Function (V. Gurevich, et al.).\u003cbr\u003e \u003cbr\u003e The G Protein-Coupled Receptor Phosphatase (J. Pitcher \u0026amp; R. Lefkowitz).\u003cbr\u003e \u003cbr\u003e REGULATION OF RECEPTOR TRAFFICKING AND EXPRESSION.\u003cbr\u003e \u003cbr\u003e Radioligand Binding Assays for G Protein-Coupled Receptor Internalization (M. Toews).\u003cbr\u003e \u003cbr\u003e Characterization of Receptor Sequestration by Immunofluorescent Microscopy (F. Santini \u0026amp; J. Keen).\u003cbr\u003e \u003cbr\u003e Characterization of Receptor Trafficking Using Green Fluorescent Protein (N. Tarasova, et al.).\u003cbr\u003e \u003cbr\u003e The Analysis of Post-Transciptional Regulation of the Expression of G Protein-Coupled Receptors (B. Tholanikunnel \u0026amp; C. Malbon).\u003cbr\u003e \u003cbr\u003e Index.","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402543538519,"sku":"9780471252771","price":280.76,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/regulation-of-g-protein-coupled-receptor-function-and-expression-9780471252771","provider":"Book Curl","version":"1.0","type":"link"}