{"product_id":"protein-interactions-the-molecular-basis-of-interactomics-9783527348640","title":"Protein Interactions: The Molecular Basis of","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eProtein Interactions\u003c\/b\u003e \u003cp\u003e\u003cb\u003eA fundamental guide to the burgeoning field of protein interactions\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003eFrom enzymes to transcription factors to cell membrane receptors, proteins are at the heart of biological cell function. Virtually all cellular processes are governed by their interactions, with one another, with cell bodies, with DNA, or with small molecules. The systematic study of these interactions is called Interactomics, and research within this new field promises to shape the future of molecular cell biology. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eProtein Interactions \u003c\/i\u003egoes beyond any existing guide to protein interactions, presenting the first truly comprehensive overview of the field. Edited by two leading scholars in the field of protein bioinformatics, this book covers all known categories of protein interaction, stable as well as transient, as well as the effect of mutations and post-translational modifications on the interaction behavior. \u003c\/p\u003e\u003cp\u003e\u003ci\u003eProtein Interactions \u003c\/i\u003ereaders will also find: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e Introductory chapters on protein structure, conformational dynamics, and protein-protein binding interfaces\u003c\/li\u003e\n\u003cli\u003e A data-driven approach incorporating machine learning and integrating experimental data into computational models\u003c\/li\u003e\n\u003cli\u003e An outlook on the current challenges in the field and suggestions for future research\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eProtein Interactions\u003c\/i\u003e will serve as a fundamental resource for novice researchers who want a systematic introduction to interactomics, as well as for experienced cell biologists and bioinformaticians who want to gain an edge in this exciting new field.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eProteins: structure and conformational dynamics\u003cbr\u003e Protein binding interfaces\u003cbr\u003e Structures, composition, and modelling of protein complexes\u003cbr\u003e Kinetics and energetics of protein-protein encounter\u003cbr\u003e Markov-state models for protein-protein encounter\u003cbr\u003e Correlated, co-evolving mutations at PP interfaces\u003cbr\u003e Protein-protein-docking\u003cbr\u003e Predicting interacting proteins by deep learning\u003cbr\u003e Interactions of membrane proteins\u003cbr\u003e Mass spectrometry to detect stoichiometries of protein complexes\u003cbr\u003e Data resources on protein interactomics\u003cbr\u003e Data integration to resolve composition of very large protein complexes\u003cbr\u003e Cellular protein complexeomes\u003cbr\u003e Interactions of transcription factors with DNA\u003cbr\u003e Interactions of chromatin remodeling proteins and epigenetic reader\/writer proteins with DNA\u003cbr\u003e Interactions of proteins with mRNA\u003cbr\u003e Interactions of proteins with biological membranes\u003cbr\u003e Interactions of proteins with small molecules\u003cbr\u003e Small molecule inhibitors of protein interactions\u003cbr\u003e Binding pockets on protein surfaces\u003cbr\u003e Effects of protein mutations on their interactions\u003cbr\u003e Effects of alternative splicing on protein interactions\u003cbr\u003e Effects of post-translational modifications on protein interactions\u003cbr\u003e Summary and outlook","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":49419452973399,"sku":"9783527348640","price":121.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783527348640.jpg?v=1730538353","url":"https:\/\/bookcurl.com\/products\/protein-interactions-the-molecular-basis-of-interactomics-9783527348640","provider":"Book Curl","version":"1.0","type":"link"}