{"product_id":"oral-formulation-roadmap-from-early-drug-discovery-to-development-9781118907337","title":"Oral Formulation Roadmap from Early Drug","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eDetailing formulation approaches by stage of discovery to early development, this book gives a playbook of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development. \u003cbr\u003e\u003cbr\u003e Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry\u003cbr\u003e Focuses on pre (or non-) clinical and early stage development, the phases where most compounds are used in drug research\u003cbr\u003e Features case studies to illustrate practical challenges and solutions in formulation selection\u003cbr\u003e Covers regulatory filing, drug metabolism and physical and chemical properties, toxicology formulation, biopharmaceutics classification system (BCS), screening approaches, early stage clinical formulation development, and outsourcing\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of Contributors vii\u003c\/p\u003e \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003e1 Introduction 1\u003cbr\u003e\u003ci\u003eElizabeth Kwong\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Lead Identification\/Optimization 9\u003cbr\u003e\u003ci\u003eMei Wong and Mark McAllister\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Oral Drug Formulation Development in Pharmaceutical Lead Selection Stage 39\u003cbr\u003e\u003ci\u003eShayne Cox Gad\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Bridging End of Discovery to Regulatory Filing: Formulations for IND-and Registration-Enabling Nonclinical Studies 89\u003cbr\u003e\u003ci\u003eEvan A. Thackaberry\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Planning the First Clinical Trials with Clinical Manufacturing Organization (CMO) 115\u003cbr\u003e\u003ci\u003eElizabeth Kwong and Caroline McGregor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Formulation Strategies for High Dose Toxicology Studies: Case Studies 139\u003cbr\u003e\u003ci\u003eDennis H. Leung, Pierre Daublain, Mengwei Hu and Kung]I Feng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Formulation, Analytical, and Regulatory Strategies for First-in-Human Clinical Trials 165\u003cbr\u003e\u003ci\u003eLorenzo Capretto, Gerard Byrne, Sarah Trenfield, Lee Dowden and Steven Booth\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 243\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49528840782167,"sku":"9781118907337","price":124.4,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118907337.jpg?v=1731873229","url":"https:\/\/bookcurl.com\/products\/oral-formulation-roadmap-from-early-drug-discovery-to-development-9781118907337","provider":"Book Curl","version":"1.0","type":"link"}