{"product_id":"opsinfree-optogenetics-9781032249223","title":"Opsinfree Optogenetics","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eOptogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating the temporal and spatial profile of light enabled precise control of membrane potentials. This feature has inspired non-opsin-based optogenetics, which not only inherits the precise spatiotemporal resolution but also expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels, kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools. \u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eKey Features \u003c\/p\u003e\u003cul\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eDescribes new developments in non-opsin-based optogenetic tools \u003c\/li\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003cli\u003eIntroduces cutting-edge methods for precise modulation of cell signaling \u003c\/li\u003e\n\u003cp\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003e“This book differs markedly from these other, more general volumes by \u003c\/i\u003e\u003ci\u003evirtue of its concentration on next generation, non-opsin photo-switches. The \u003c\/i\u003e\u003ci\u003eresult is a focused, highly informative, yet compact and easy-to-read volume \u003c\/i\u003e\u003ci\u003ethat offers a model for how these works should be constructed.”\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003eDoody Review Peter J. Kennelly, PhD (Virginia Tech)\u003c\/p\u003e\n\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eTable of Content\u003c\/p\u003e\n\u003cp\u003eChapter 1 \u003c\/p\u003e\n\u003cp\u003eOptogenetic dissection of a two-component calcium influx pathway \u003c\/p\u003e\n\u003cp\u003eXiaoxuan Liu, Yingshan Wang, Yubin Zhou, and \u003cb\u003eGuolin Ma* \u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 2 \u003c\/p\u003e\n\u003cp\u003eHigh-throughput engineering of a light-activatable Ca2+ channel \u003c\/p\u003e\n\u003cp\u003eLian He*, Liuqing Wang, and \u003cb\u003eYoujun Wang*\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 3 \u003c\/p\u003e\n\u003cp\u003eOptogenetic activation of TrkB signaling \u003c\/p\u003e\n\u003cp\u003ePeiyuan Huang, Zhihao Zhao, Lei Lei, and \u003cb\u003eLiting Duan* \u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 4 \u003c\/p\u003e\n\u003cp\u003eSpatiotemporal modulation of neural repair \u003c\/p\u003e\n\u003cp\u003eHuaxun Fan, Qin Wang, \u003cb\u003eKai Zhang*\u003c\/b\u003e, and \u003cb\u003eYuanquan Song* \u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 5 \u003c\/p\u003e\n\u003cp\u003eOptogenetic control of neural stem cell differentiation \u003c\/p\u003e\n\u003cp\u003eYixun Su, Taida Huang, Kai Zhang, and \u003cb\u003eChenju Yi* \u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 6 \u003c\/p\u003e\n\u003cp\u003eAn optogenetic toolbox for remote control of programmed cell death \u003c\/p\u003e\n\u003cp\u003eNingxia Zhang and \u003cb\u003eJi Jing*\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 7 \u003c\/p\u003e\n\u003cp\u003eControl of protein levels in Saccharomyces cerevisiae by optogenetic modules that act on protein synthesis and stability \u003c\/p\u003e\n\u003cp\u003eSophia Hasenjäger, Jonathan Trauth, and \u003cb\u003eChristof Taxis*\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 8 \u003c\/p\u003e\n\u003cp\u003eOptogenetics as a tool to study neurodegeneration and signal transduction \u003c\/p\u003e\n\u003cp\u003ePrabhat Tiwari* and \u003cb\u003eNicholas S. Tolwinski*\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 9 \u003c\/p\u003e\n\u003cp\u003eOpsin-free optogenetics: brain and beyond\u003c\/p\u003e\n\u003cp\u003eJongryul Hong, Yeonji Jeong, and \u003cb\u003eWon Do Heo*\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 10 \u003c\/p\u003e\n\u003cp\u003eConstructing a far-red light-induced split-Cre recombinase system for controllable genome engineering \u003c\/p\u003e\n\u003cp\u003eMeiyan Wang, Jiali Wu, and \u003cb\u003eHaifeng Ye*\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eChapter 11 \u003c\/p\u003e\n\u003cp\u003eTools and Technologies for Wireless and Non-invasive Optogenetics \u003c\/p\u003e\n\u003cp\u003eGuangfu Wu, Vagif Abdulla, Yiyuan Yang, Michael Schneider, and \u003cb\u003eYi Zhang*\u003c\/b\u003e\u003c\/p\u003e\n\u003c\/ul\u003e","brand":"Taylor \u0026 Francis Ltd","offers":[{"title":"Default Title","offer_id":51018923868503,"sku":"9781032249223","price":82.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781032249223.jpg?v=1750778681","url":"https:\/\/bookcurl.com\/products\/opsinfree-optogenetics-9781032249223","provider":"Book Curl","version":"1.0","type":"link"}