{"product_id":"octanolwater-partition-coefficients-9780471973973","title":"OctanolWater Partition Coefficients","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe octanol-water partition coefficient is a laboratory-measured property of a substance. It provides a thermodynamic measure of the tendency of the substance to prefer a non-aqueous or oily milieu rather than water (i.e. its hydrophilic\/lipophilic balance). Partition coefficients are used extensively in medicinal chemistry, drug design, ecotoxicology and environmental chemistry. The partition coefficient is recognized by governmental and international agencies (U.S. Environmental Protection Agency, OECD) as a physical property of organic pollutants equal in importance to vapour pressure, water solubility and toxicity. Octanol-Water Partition Coefficients is a comprehensive and up-to-date survey of the thermodynamics of partitioning and of the octanol-water pair. In addition, all current methods of measurement are reviewed, strengths and weaknesses are noted and recommendations for particular applications are given. Current methods of calculation of partition coefficients are similarly\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eThermodynamics and Extrathermodynamics of Partitioning.\u003cbr\u003e \u003cbr\u003e Experimental Methods of Measurement.\u003cbr\u003e \u003cbr\u003e Discussion of Measurement Methods.\u003cbr\u003e \u003cbr\u003e Methods of Calculating Partition Coefficients.\u003cbr\u003e \u003cbr\u003e Discussion on Log Kow Predictive Methods.\u003cbr\u003e \u003cbr\u003e Appendix.\u003cbr\u003e \u003cbr\u003e Index.","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402702987607,"sku":"9780471973973","price":328.46,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780471973973.jpg?v=1730481285","url":"https:\/\/bookcurl.com\/products\/octanolwater-partition-coefficients-9780471973973","provider":"Book Curl","version":"1.0","type":"link"}