{"product_id":"nutraceuticals-and-human-blood-platelet-function-9781119376019","title":"Nutraceuticals and Human Blood Platelet Function","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eA comprehensive review of the impact of dietary nutraceuticals on platelet function and its relationship to cardiovascular disease\u003c\/b\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eNutraceuticals and Human Blood Platelet Function \u003c\/i\u003eoffers a summary of the most current evidence on the effects of anti-platelet factors isolated mainly from food and natural sources, their structure function relationship, bioavailability, mechanisms of actions, and also information on human trials data. The authora noted expert in the field explores platelet function and their roles in development of CVD, functional foods and bioactive compounds in CVD risk factors. The author highlights platelets, their mechanisms of actions, data from epidemiological studies, structure-function relationship clinical trial data, ex vivo and in vitro data.\u003c\/p\u003e \u003cp\u003eThis important resource will focus primarily on human studies and emphasize functional and physiological implications of the nutritional impact on platelet function and CVD that could \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003e1 Human Blood Platelets and Their Role in the Development of Cardiovascular Disease 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 1\u003c\/p\u003e \u003cp\u003e1.1 Introduction 1\u003c\/p\u003e \u003cp\u003e1.2 Human Blood Platelets: Structure and Function 4\u003c\/p\u003e \u003cp\u003e1.3 Platelet Activation Pathways 10\u003c\/p\u003e \u003cp\u003e1.4 Platelets and Vessel Wall Interactions 12\u003c\/p\u003e \u003cp\u003e1.5 Roles of Platelets in Atherosclerosis and Inflammatory Processes 13\u003c\/p\u003e \u003cp\u003e1.6 Platelets and Their Role in the Development of Cardiovascular Disease 17\u003c\/p\u003e \u003cp\u003e1.7 Conclusions 22\u003c\/p\u003e \u003cp\u003eReferences 22\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Epidemiology of Cardiovascular Disease 29\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 29\u003c\/p\u003e \u003cp\u003e2.1 Introduction 29\u003c\/p\u003e \u003cp\u003e2.2 Dietary Lipids and Cardiovascular Disease 32\u003c\/p\u003e \u003cp\u003e2.3 Environmental Factors and Cardiovascular Disease 34\u003c\/p\u003e \u003cp\u003e2.4 Genetic Basis of Cardiovascular Disease Incidence 35\u003c\/p\u003e \u003cp\u003e2.5 Fruits and Vegetables Consumption and Cardiovascular Disease Risk Reduction 37\u003c\/p\u003e \u003cp\u003e2.6 Conclusions 40\u003c\/p\u003e \u003cp\u003eReferences 40\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 n‐3 Fatty Acids and Human Platelets 47\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 47\u003c\/p\u003e \u003cp\u003e3.1 Introduction 47\u003c\/p\u003e \u003cp\u003e3.2 Epidemiology of n‐3 Fatty Acids Intake and Cardiovascular Disease 51\u003c\/p\u003e \u003cp\u003e3.3 n‐3 Fatty Acids and Platelet Function 52\u003c\/p\u003e \u003cp\u003e3.4 Platelet Function and Eicosanoids 56\u003c\/p\u003e \u003cp\u003e3.5 Clinical Trials with n‐3 Fatty Acids 59\u003c\/p\u003e \u003cp\u003e3.6 Dietary Recommendation and Sources of n‐3 Fatty Acids 61\u003c\/p\u003e \u003cp\u003e3.7 Conclusions 62\u003c\/p\u003e \u003cp\u003eReferences 62\u003c\/p\u003e \u003cp\u003e4 Effects of Garlic, Onion, Ginger, and Turmeric on Platelet Function 69\u003c\/p\u003e \u003cp\u003eAbbreviations 69\u003c\/p\u003e \u003cp\u003e4.1 Introduction 69\u003c\/p\u003e \u003cp\u003e4.2 Effects of Garlic (\u003ci\u003eAllium Sativum\u003c\/i\u003e) on Platelet Function 71\u003c\/p\u003e \u003cp\u003e4.3 Effects of Onion (\u003ci\u003eAllium Cepa L.\u003c\/i\u003e) on Platelet Function 74\u003c\/p\u003e \u003cp\u003e4.4 Effects of Ginger (\u003ci\u003eZingiber Officinale\u003c\/i\u003e) on Platelet Function 75\u003c\/p\u003e \u003cp\u003e4.5 Effects of Turmeric (\u003ci\u003eCurcuma Longa\u003c\/i\u003e) on Platelets 76\u003c\/p\u003e \u003cp\u003e4.6 Conclusions 78\u003c\/p\u003e \u003cp\u003eReferences 79\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Herbs and Platelet Function 83\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 83\u003c\/p\u003e \u003cp\u003e5.1 Introduction 83\u003c\/p\u003e \u003cp\u003e5.\u003ci\u003e2 In Vitro\u003c\/i\u003e Platelet Aggregation Studies: Effects of Different Herb Extracts 87\u003c\/p\u003e \u003cp\u003e5.2.1 Andrographis (\u003ci\u003eAndrographis Paniculata\u003c\/i\u003e) 89\u003c\/p\u003e \u003cp\u003e5.2.2 Cranberry (\u003ci\u003eVaccinium Macrocarpon\u003c\/i\u003e) 90\u003c\/p\u003e \u003cp\u003e5.2.3 Feverfew (\u003ci\u003eTanacetum Parthenium\u003c\/i\u003e) 90\u003c\/p\u003e \u003cp\u003e5.2.4 Green Tea (\u003ci\u003eCamellia Sinensis\u003c\/i\u003e) 91\u003c\/p\u003e \u003cp\u003e5.2.5 Hawthorn (\u003ci\u003eCrataegus Oxyacantha\u003c\/i\u003e) 92\u003c\/p\u003e \u003cp\u003e5.2.6 Horse Chestnut (\u003ci\u003eAesculus Hippocastanum\u003c\/i\u003e) 92\u003c\/p\u003e \u003cp\u003e5.2.7 Motherwort (\u003ci\u003eLeonurus Japonicus\u003c\/i\u003e) 93\u003c\/p\u003e \u003cp\u003e5.2.8 St John’s Wort (\u003ci\u003eHypericum Perforatum\u003c\/i\u003e) 93\u003c\/p\u003e \u003cp\u003e5.2.9 Willow Bark (\u003ci\u003eSalix Alba\u003c\/i\u003e) 94\u003c\/p\u003e \u003cp\u003e5.3 Effects of Herbs on Signaling Molecules in Human Platelets 95\u003c\/p\u003e \u003cp\u003e5.4 Conclusions 97\u003c\/p\u003e \u003cp\u003eReferences 98\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Tomato Extract and Human Platelet Functions 101\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 101\u003c\/p\u003e \u003cp\u003e6.1 Introduction 101\u003c\/p\u003e \u003cp\u003e6.2 Epidemiology of Tomato Consumption and Cardiovascular Disease Risk Reduction 104\u003c\/p\u003e \u003cp\u003e6.3 \u003ci\u003eIn Vitro\u003c\/i\u003e Studies with Water‐Soluble Tomato Extract on Human Blood Platelet Aggregation 105\u003c\/p\u003e \u003cp\u003e6.4 Fruitflow\u003csup\u003e®\u003c\/sup\u003e: Compositional and Structural Aspects 111\u003c\/p\u003e \u003cp\u003e6.5 Human Trials 112\u003c\/p\u003e \u003cp\u003e6.6 Comparing the Dietary Anti‐Platelet Fruitflow\u003csup\u003e®\u003c\/sup\u003e with the Anti‐Platelet Drug Aspirin 115\u003c\/p\u003e \u003cp\u003e6.8 EFSA Approval of Fruitflow\u003csup\u003e®\u003c\/sup\u003e 117\u003c\/p\u003e \u003cp\u003e6.8 Conclusions 117\u003c\/p\u003e \u003cp\u003eReferences 118\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Dietary Nitrates and Their Anti‐Platelet Effects 125\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 125\u003c\/p\u003e \u003cp\u003e7.1 Introduction 125\u003c\/p\u003e \u003cp\u003e7.2 Nitrate and Cardiovascular Health 129\u003c\/p\u003e \u003cp\u003e7.3 Effects of Nitrates on Human Blood Platelet Function \u003ci\u003eIn Vitro\u003c\/i\u003e 131\u003c\/p\u003e \u003cp\u003e7.4 Clinical Studies with Dietary Nitrate: Effects on Ex Vivo Platelet Function 133\u003c\/p\u003e \u003cp\u003e7.5 Conclusions 134\u003c\/p\u003e \u003cp\u003eReferences 135\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Kiwifruit and Human Platelet Function 139\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 139\u003c\/p\u003e \u003cp\u003e8.1 Introduction 139\u003c\/p\u003e \u003cp\u003e8.2 Kiwifruit and Its Bioactive Phytochemicals 140\u003c\/p\u003e \u003cp\u003e8.3 Kiwifruits and Human Blood Platelet Function 141\u003c\/p\u003e \u003cp\u003e8.4 Human Trials Using Kiwifruit and Kiwifruit Extract 147\u003c\/p\u003e \u003cp\u003e8.5 Conclusions 150\u003c\/p\u003e \u003cp\u003eReferences 151\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Polyphenols and Human Platelets 155\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 155\u003c\/p\u003e \u003cp\u003e9.1 Introduction 155\u003c\/p\u003e \u003cp\u003e9.2 Polyphenols: Structure and Activity 157\u003c\/p\u003e \u003cp\u003e9.3 Sources of Polyphenols 159\u003c\/p\u003e \u003cp\u003e9.4 Dietary Intakes and Bioavailability of Polyphenols 160\u003c\/p\u003e \u003cp\u003e9.5 Roles of Polyphenols in Platelet Function 161\u003c\/p\u003e \u003cp\u003e9.6 Conclusions 167\u003c\/p\u003e \u003cp\u003eReferences 168\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Effects of Ginkgo Biloba, Ginseng, Green Tea, and Dark Chocolate on Human Blood Platelet Function 171\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 171\u003c\/p\u003e \u003cp\u003e10.1 Introduction 171\u003c\/p\u003e \u003cp\u003e10.2 Ginkgo Biloba Extract and Platelet Function 172\u003c\/p\u003e \u003cp\u003e10.3 Clinical Trial with EGB761 175\u003c\/p\u003e \u003cp\u003e10.4 Ginseng and Platelet Function 177\u003c\/p\u003e \u003cp\u003e10.5 Green Tea (\u003ci\u003eCamellia Sinensis\u003c\/i\u003e) and its Effects on Platelet Function 181\u003c\/p\u003e \u003cp\u003e10.6 Dark Chocolate and Platelet Function 183\u003c\/p\u003e \u003cp\u003e10.7 Conclusions 185\u003c\/p\u003e \u003cp\u003eReferences 187\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Plant Alkaloids and Platelet Function 191\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 191\u003c\/p\u003e \u003cp\u003e11.1 Introduction 191\u003c\/p\u003e \u003cp\u003e11.2 Alkaloids as Anti‐Platelet Agents 193\u003c\/p\u003e \u003cp\u003e11.3 Mechanism of Actions of Alkaloids 197\u003c\/p\u003e \u003cp\u003e11.4 Conclusions 198\u003c\/p\u003e \u003cp\u003eReferences 199\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Strawberries and Human Platelet Function 203\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 203\u003c\/p\u003e \u003cp\u003e12.1 Introduction 203\u003c\/p\u003e \u003cp\u003e12.2 Polyphenols in Strawberries 204\u003c\/p\u003e \u003cp\u003e12.3 Strawberry and its Cardio‐Protective Effects 206\u003c\/p\u003e \u003cp\u003e12.4 Anti‐Platelet Factors in Strawberry 207\u003c\/p\u003e \u003cp\u003e12.5 Discussion 209\u003c\/p\u003e \u003cp\u003eReferences 211\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Effects of Metal Ions on Platelet Function 215\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 215\u003c\/p\u003e \u003cp\u003e13.1 Introduction 215\u003c\/p\u003e \u003cp\u003e13.2 Zinc and Human Blood Platelet Function 216\u003c\/p\u003e \u003cp\u003e13.3 Calcium and its Regulation of Platelet Function 218\u003c\/p\u003e \u003cp\u003e13.4 Chromium and Platelet Function 221\u003c\/p\u003e \u003cp\u003e13.5 Iron (Fe) and Platelet Function 221\u003c\/p\u003e \u003cp\u003e13.6 Magnesium and Platelet Function 222\u003c\/p\u003e \u003cp\u003e13.7 Platelet Function and Selenium 223\u003c\/p\u003e \u003cp\u003e13.8 Conclusions 225\u003c\/p\u003e \u003cp\u003eReferences 226\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Individual Compounds with Anti‐Platelet Activity\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eIsolated from Plant Sources 231\u003c\/p\u003e \u003cp\u003eAbbreviations Used in This Chapter 231\u003c\/p\u003e \u003cp\u003e14.1 Introduction 231\u003c\/p\u003e \u003cp\u003e14.2 Effects of Taurine and Glycine on Human Platelets 233\u003c\/p\u003e \u003cp\u003e14.3 Anthocyanins and Human Platelets 234\u003c\/p\u003e \u003cp\u003e14.4 Coumarins and Their Anti‐Platelet Effects 235\u003c\/p\u003e \u003cp\u003e14.5 Atractylenolides and Their Anti‐Platelet Effects 236\u003c\/p\u003e \u003cp\u003e14.6 Flavonolignans and Blood Platelet Function 238\u003c\/p\u003e \u003cp\u003e14.7 Protocatechuic Acid on Human Platelet Aggregation 238\u003c\/p\u003e \u003cp\u003e14.8 KOK and Platelet Function 240\u003c\/p\u003e \u003cp\u003e14.9 Inhibitors of Platelet Granules Secretion 241\u003c\/p\u003e \u003cp\u003e14.10 Hydroxychavicol and Platelet Function 243\u003c\/p\u003e \u003cp\u003e14.11 Compounds Isolated from \u003ci\u003eGuttiferae\u003c\/i\u003e Species with Anti‐Platelet Activity 243\u003c\/p\u003e \u003cp\u003e14.12 Conclusions 244\u003c\/p\u003e \u003cp\u003eReferences 244\u003c\/p\u003e \u003cp\u003eIndex 247\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49407041241431,"sku":"9781119376019","price":125.35,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119376019.jpg?v=1730497972","url":"https:\/\/bookcurl.com\/products\/nutraceuticals-and-human-blood-platelet-function-9781119376019","provider":"Book Curl","version":"1.0","type":"link"}