{"product_id":"nanodiamonds-in-analytical-and-biological-sciences-9781394202133","title":"Nanodiamonds in Analytical and Biological","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eNANODIAMONDS \u003csmall cap\u003eIN\u003c\/small\u003e ANALYTICAL \u003csmall cap\u003eAND\u003c\/small\u003e BIOLOGICAL SCIENCES\u003c\/b\u003e \u003cp\u003e\u003cb\u003eComprehensive resource highlighting the significance and applications of fluorescent and non-fluorescent nanodiamonds in various domains\u003c\/b\u003e \u003c\/p\u003e\u003cp\u003e\u003ci\u003eNanodiamonds in Analytical and Biological Sciences\u003c\/i\u003e combines the disciplines of chemistry, physics, materials science, and biology to demonstrate the significance of nanodiamonds, offering precise analysis of the impacts and up-to-date applications of fluorescent and non-fluorescent nanodiamonds, including in COVID-19 and artificial intelligence, with illustrations, case studies, practical examples, and novel perspectives included throughout. \u003c\/p\u003e\u003cp\u003eEdited by two highly qualified scholars with significant experience in the field, topics covered include: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eFundamental properties, synthesis, mechanisms, and functionalization of nanodiamonds, and toxicity assessment\u003c\/li\u003e \u003cli\u003eFabrication and surface modification of fluorescent nanod\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eContributors xii\u003c\/p\u003e \u003cp\u003eEditor's Preface: Nanodiamonds -- A Rising Star in Nanotechnology xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Nanodiamonds 1\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eTan-Thanh Huynh, Marvin Chen, Thi-Hong-Hanh Le, Xuan Mai Lam, Kartika Wardhani, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Structure and Classification of Nanodiamonds 1\u003c\/p\u003e \u003cp\u003e1.2 Preparation of Nanodiamonds 4\u003c\/p\u003e \u003cp\u003e1.2.1 High-Pressure, High-Temperature 5\u003c\/p\u003e \u003cp\u003e1.2.2 Detonation Technique 6\u003c\/p\u003e \u003cp\u003e1.2.3 Chemical Vapor Deposition 7\u003c\/p\u003e \u003cp\u003e1.2.4 Alternative Methods of Producing Nanodiamonds 8\u003c\/p\u003e \u003cp\u003e1.3 Physical and Chemical Properties of Nanodiamonds 9\u003c\/p\u003e \u003cp\u003e1.4 Colloidal Properties of Nanodiamonds 12\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Fluorescent Nanodiamonds 19\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eWesley Wei-Wen Hsiao, Hsuan-Yi Lin, Ming-Wei Jen, Tan-Thanh Huynh, Thi-Hong-Hanh Le, and Yan-Kai Tzeng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction to Fluorescent Nanodiamonds 19\u003c\/p\u003e \u003cp\u003e2.2 Optical Properties of Fluorescent Nanodiamonds 21\u003c\/p\u003e \u003cp\u003e2.2.1 Vacancy-Related Color Centers 22\u003c\/p\u003e \u003cp\u003e2.2.2 Negative Nitrogen-Vacancy Center 23\u003c\/p\u003e \u003cp\u003e2.2.3 Silicon-Vacancy Center 25\u003c\/p\u003e \u003cp\u003e2.3 Introduction to Förster Resonance Energy Transfer 26\u003c\/p\u003e \u003cp\u003e2.3.1 Theory 27\u003c\/p\u003e \u003cp\u003e2.3.2 FRET Efficiency 28\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Fabrication of Fluorescent Nanodiamonds 35\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eWesley Wei-Wen Hsiao, Jo-Yu Wang, Syun-Ying Wang, Stefanny Angela, and Yan-Kai Tzeng\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction to FND Fabrication 35\u003c\/p\u003e \u003cp\u003e3.2 Theoretical Simulations 36\u003c\/p\u003e \u003cp\u003e3.3 Production and Characterization of Fluorescent Nanodiamonds 39\u003c\/p\u003e \u003cp\u003e3.4 Latest Developments in High-Pressure, High-Temperature Fluorescent Nanodiamonds 41\u003c\/p\u003e \u003cp\u003e3.5 Production of Ultrasmall Fluorescent Nanodiamonds 42\u003c\/p\u003e \u003cp\u003e3.6 Synthesis of Highly Dispersible Fluorescent Nanodiamonds 45\u003c\/p\u003e \u003cp\u003e3.7 Brightly Synthesized Fluorescent Nanodiamonds Using Solar Energy 46\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Surface Modification of Nanodiamonds 52\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eStefanny Angela, Tzu-Chun You, Dinh Minh Pham, Trong-Nghia Le, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Surface Modification of Nanodiamonds 52\u003c\/p\u003e \u003cp\u003e4.2 Surface Functionalization of Nanodiamonds 53\u003c\/p\u003e \u003cp\u003e4.3 Encapsulation of Nanodiamonds 55\u003c\/p\u003e \u003cp\u003e4.4 Bioconjugation of Nanodiamonds 58\u003c\/p\u003e \u003cp\u003e4.5 Application of Surface-Modified Nanodiamonds 60\u003c\/p\u003e \u003cp\u003e4.5.1 Biotechnological Applications 60\u003c\/p\u003e \u003cp\u003e4.5.2 Biomedical Applications 63\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Toxicity Assessments of Nanodiamonds 73\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eDuc-Thang Vo, Tzu-Syuan You, Yu-Teng Lin, Stefanny Angela, Trong-Nghia Le, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Cellular Uptake of Fluorescent Nanodiamonds 73\u003c\/p\u003e \u003cp\u003e5.2 In vitro Assessments 75\u003c\/p\u003e \u003cp\u003e5.3 In vivo Assessments 80\u003c\/p\u003e \u003cp\u003e5.4 Nanodiamonds' Phytotoxic Effect 87\u003c\/p\u003e \u003cp\u003e5.5 Role of Oxidative Stress in Nanodiamonds' Toxicity 88\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 In vitro Bioimaging of Fluorescent Nanodiamonds 95\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eTrong-Nghia Le, Yen-Tse Chiang, Yuen Yung Hui, Thi-Hong-Hanh Le, Yan-Kai Tzeng, Neha Sharma, Wei-Hung Chiang, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Bioimaging Applications 95\u003c\/p\u003e \u003cp\u003e6.2 Epifluorescence and Confocal Fluorescence Imaging 96\u003c\/p\u003e \u003cp\u003e6.3 Single-Particle Tracking 98\u003c\/p\u003e \u003cp\u003e6.4 Two-Photon Fluorescence Imaging 102\u003c\/p\u003e \u003cp\u003e6.5 Fluorescence Lifetime Imaging 103\u003c\/p\u003e \u003cp\u003e6.5.1 Introduction to Fluorescence Lifetime Imaging Microscopy 103\u003c\/p\u003e \u003cp\u003e6.5.2 Principles of FLIM 104\u003c\/p\u003e \u003cp\u003e6.5.3 Time-Correlated Single-Photon Counting 105\u003c\/p\u003e \u003cp\u003e6.5.4 FND for FLIM 105\u003c\/p\u003e \u003cp\u003e6.6 Super-Resolution Fluorescence Imaging 108\u003c\/p\u003e \u003cp\u003e6.6.1 Introduction to STED Microscopy 108\u003c\/p\u003e \u003cp\u003e6.6.2 Principle of STED 109\u003c\/p\u003e \u003cp\u003e6.6.3 FND-Enabled STED 111\u003c\/p\u003e \u003cp\u003e6.6.4 Combining STED with other Techniques for Bioimaging 113\u003c\/p\u003e \u003cp\u003e6.7 Optically Detected Magnetic Resonance Imaging 115\u003c\/p\u003e \u003cp\u003e6.8 Cathodoluminescence Imaging 117\u003c\/p\u003e \u003cp\u003e6.9 Correlative Light and Electron Microscopy 120\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 In Vivo Bioimaging of Fluorescent Nanodiamonds 128\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eWesley Wei-Wen Hsiao, Yun-Yu Chen, Thi-Hong-Hanh Le, Yuen Yung Hui, Stefanny Angela, and Trong-Nghia Le\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Wide-Field Fluorescence Imaging 128\u003c\/p\u003e \u003cp\u003e7.2 Time-Gated Fluorescence Imaging 129\u003c\/p\u003e \u003cp\u003e7.3 Photoacoustic Imaging 131\u003c\/p\u003e \u003cp\u003e7.4 Tissue Imaging by Microwave Modulation 133\u003c\/p\u003e \u003cp\u003e7.5 Magnetically Modulated Fluorescence Imaging 135\u003c\/p\u003e \u003cp\u003e7.6 Tissue Imaging Combining Microwaves and Quadruple Coils 137\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Quantum Sensing of Fluorescent Nanodiamonds 141\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eYuen Yung Hui, Miranda Liu, Stefanny Angela, Thi-Hong-Hanh Le, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Quantum Coherence 141\u003c\/p\u003e \u003cp\u003e8.2 NV -- Centers for Quantum Sensing 143\u003c\/p\u003e \u003cp\u003e8.3 Emerging Sensing Technologies Using FND 146\u003c\/p\u003e \u003cp\u003e8.3.1 Magnetic Field Sensor 146\u003c\/p\u003e \u003cp\u003e8.3.2 Orientation Tracker for NV Axis 150\u003c\/p\u003e \u003cp\u003e8.3.3 Nanoscopic Spin Probe 151\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Nanoscale Thermometry with Fluorescent Nanodiamonds 156\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eThi-Hong-Hanh Le, Richard Hsin, Duc-Thang Vo, Yan-Kai Tzeng, Trong-Nghia Le, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 NV Thermometry in Biosystems 156\u003c\/p\u003e \u003cp\u003e9.2 Ultrahigh Precision Temperature Measurement 157\u003c\/p\u003e \u003cp\u003e9.3 Time-Resolved Nanothermometry 158\u003c\/p\u003e \u003cp\u003e9.4 All-Optical Luminescence Nanothermometry 159\u003c\/p\u003e \u003cp\u003e9.5 Scanning Thermal Imaging 161\u003c\/p\u003e \u003cp\u003e9.6 Intracellular Temperature Sensing 161\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Nanodiamond-Enabled Drug Delivery 171\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eStefanny Angela, Raymond Hsin, Steven Che-Wei Lu, Trong-Nghia Le, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 172\u003c\/p\u003e \u003cp\u003e10.2 Drug Delivery Through Nanodiamonds 173\u003c\/p\u003e \u003cp\u003e10.2.1 Delivery of Small Molecules 173\u003c\/p\u003e \u003cp\u003e10.2.2 Delivery of Peptides and Proteins 179\u003c\/p\u003e \u003cp\u003e10.2.3 Gene Delivery 184\u003c\/p\u003e \u003cp\u003e10.3 Fluorescent Nanodiamond-Based Theranostics Platform 189\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Nanodiamond for Mass-Spectrometry-Based Analysis of Peptides, Proteins, and Proteomes 198\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eDinh Minh Pham, Ryu Endo, Chris Chen-Hua Chang, Thi-Hong-Hanh Le, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Principles of Analyzing Macro Biomolecules with Mass Spectrometry 199\u003c\/p\u003e \u003cp\u003e11.2 The Post-Era of Genomics 199\u003c\/p\u003e \u003cp\u003e11.3 Bioinformatics for the Coming of Big-Data Biology 200\u003c\/p\u003e \u003cp\u003e11.4 Nanodiamonds for the Mass-Spectrometry-Based Analysis of Peptides, Proteins, and Proteomics 201\u003c\/p\u003e \u003cp\u003e11.5 Origin of Interactions Between Nanodiamonds and Proteins or Peptides 201\u003c\/p\u003e \u003cp\u003e11.5.1 Surface Properties of Carboxylated\/Oxidized Nanodiamonds 201\u003c\/p\u003e \u003cp\u003e11.5.2 Interactions of Proteins and Peptides with Carboxylated\/Oxidized Nanodiamonds 203\u003c\/p\u003e \u003cp\u003e11.5.3 Other Surface-Functionalized Nanodiamonds 206\u003c\/p\u003e \u003cp\u003e11.6 SPEED Platform for MS-Based Study of Cellular Cytoplasmic Proteins and Human Fluids 207\u003c\/p\u003e \u003cp\u003e11.7 SPEED Platform for MS-Based Study of Membrane Proteins 211\u003c\/p\u003e \u003cp\u003e11.8 Surface-Functionalized Nanodiamonds for MS-Based Study of Protein Posttranslational Modifications 215\u003c\/p\u003e \u003cp\u003e11.8.1 Nanodiamonds for the Selective Enrichment and MS-based Analysis of Phosphopeptides 215\u003c\/p\u003e \u003cp\u003e11.9 Nanodiamonds for Enrichment and MS-Based Analysis of Glycopeptides 216\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Emerging Roles of Artificial Intelligence in Nanodiamond Sensing 223\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eShahzad Ahmad Qureshi, Haroon Aman, Yu--Chen Lin, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Machine Learning Algorithms for Nanodiamond Sensing 225\u003c\/p\u003e \u003cp\u003e12.1.1 Support Vector Machine 225\u003c\/p\u003e \u003cp\u003e12.1.2 k-Nearest Neighbors 225\u003c\/p\u003e \u003cp\u003e12.1.3 Random Forest 226\u003c\/p\u003e \u003cp\u003e12.1.4 Artificial Neural Network 226\u003c\/p\u003e \u003cp\u003e12.1.5 Convolutional Neural Networks 226\u003c\/p\u003e \u003cp\u003e12.1.6 Principal Component Analysis 230\u003c\/p\u003e \u003cp\u003e12.2 Machine Learning Revolutionizes Biosensing and Disease Diagnosis 230\u003c\/p\u003e \u003cp\u003e12.3 Improving Speed and Accuracy with Magnetic Field 232\u003c\/p\u003e \u003cp\u003e12.4 Fluorescent-Nanodiamond-Based Immunomagnetic Microscopy of Tumors 233\u003c\/p\u003e \u003cp\u003e12.5 Scaling the Nanomedicine in Clinical Research 233\u003c\/p\u003e \u003cp\u003e12.6 Convolutional Neural Network Enhances Fluorescence Imaging 234\u003c\/p\u003e \u003cp\u003e12.7 Challenges and Conclusion 235\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Perspective and Outlook on Nanodiamond Research 239\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eTrong-Nghia Le, Shu-Wei Chang, Joshua Ko, Yu-Jou Lin, Wei-Hung Chiang, and Wesley Wei-Wen Hsiao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Strengths of Fluorescent Nanodiamonds 239\u003c\/p\u003e \u003cp\u003e13.2 Nanodiamond's Surface Chemistry 241\u003c\/p\u003e \u003cp\u003e13.3 Nanodiamond in Bioimaging 242\u003c\/p\u003e \u003cp\u003e13.4 Nanodiamond in Quantum Sensing 242\u003c\/p\u003e \u003cp\u003e13.5 Nanodiamond as Therapeutic Carrier 243\u003c\/p\u003e \u003cp\u003e13.6 Nanodiamond for Biomedical Analysis 243\u003c\/p\u003e \u003cp\u003e13.7 Challenges of Fluorescent Nanodiamond Research 244\u003c\/p\u003e \u003cp\u003eReferences 245\u003c\/p\u003e \u003cp\u003eIndex 247\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49407602917719,"sku":"9781394202133","price":117.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781394202133.jpg?v=1730499905","url":"https:\/\/bookcurl.com\/products\/nanodiamonds-in-analytical-and-biological-sciences-9781394202133","provider":"Book Curl","version":"1.0","type":"link"}