{"product_id":"molecular-biology-in-medicinal-chemistry-9783527304318","title":"Molecular Biology in Medicinal Chemistry","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods.\u003cbr\u003e With its examination of these novel methods and generous practical advice, this is essential reading for all pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"...a welcome addition to the library of anyone seeking to build a multidisciplinary group\" \u003cbr\u003e Applied Organometallic Chemistry, June 2004\u003cbr\u003e \u003cbr\u003e \"In all, the book touches on some of the trendiest subjects that interface to form the frontier of modern medicinal chemistry.\"\u003cbr\u003e \u003cbr\u003e Kevin G. Rice, Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, Iowa City, Journal of Medicinal Chemistry, Vol. 47, No. 26, 2004\u003cbr\u003e \u003cbr\u003e\u003cbr\u003e\"Molecular Biology in Medicinal Chemistry ist eine exzellente Einführung in einige wichtige Aspekte der pharmazeutischen Forschung und der Chemischen Biologie. Jeder Wissenschaftler, der sich für diese Gebiete interessiert, sollte über seine Bibliothek Zugriff auf dieses Buch haben.\"\u003cbr\u003e Rolf Breinbauer\u003cbr\u003e Angewandte Chemie\u003cbr\u003e \u003cbr\u003e \"It is not the book \"screening for beginners\" but, thanks to the wide range of topics, every reader will find several very interesting chapters in it. The readership is addressed in the title: medicinal chemists in industry and academia. I, for my part, found far more in it than I expected.\"\u003cbr\u003e \u003cbr\u003e Boris Schmidt\u003cbr\u003e ChemBioChem 8\/2004\u003cbr\u003e \u003cbr\u003e \"Das von Dingermann, Steinhilber und Folkers zusammengestellte Autorenteam beleuchtet in kompetenter und aufschlußreicher Weise den gegenwärtigen Stand und Stellenwert der molekularebiologischer Methoden und Techniken im Bereich der pharmazeutischen Chemie. ... \u003cbr\u003e Mit dem Themenblock Kinetik, Metabolismus und Toxikologie schließt das Buch ab. Diese hervorragende Zusammenstellung über den aktuellen Stand von Pharmacogenomics und Toxicogenomics sowie die umfassende und detaillierte Referenzliste setzt Maßstäbe und wäre allein schon Grund genug das Buch zu erwerben.\"\u003cbr\u003e \u003cbr\u003e Stefan Müller, Köln, Arzneimittel-Forschung\/Drug Research, 1\/05\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eMOLECULAR TARGETS\u003cbr\u003e Cellular Assays in Drug Discovery\u003cbr\u003e Gene Knockout Models\u003cbr\u003e Reporter Gene Assay Systems for the Investigation of GPCRs\u003cbr\u003e From the Human Genome to New Drugs: The Potential of Orphan GPCRs\u003cbr\u003e SYNTHESIS\u003cbr\u003e Stereoselective Synthesis with the Help of Recombinant Enzymes\u003cbr\u003e Nucleic Acid Drugs\u003cbr\u003e ANALYSIS\u003cbr\u003e Recent Trends in Enantioseparation of Chiral Drugs\u003cbr\u003e Affinity Chromatography\u003cbr\u003e NMR-based Drug Discovery\u003cbr\u003e 13C- and 15N-Isotopic Labeling of Proteins\u003cbr\u003e Antibody Fragments as Crystallization Enhancers\u003cbr\u003e KINETICS, METABOLISM AND TOXICOLOGY\u003cbr\u003e Pharmacogenetics: The Effect of Inherited Genetic Variation on Drug Disposition and Drug Response\u003cbr\u003e Pharmacogenomics of Bioavaliability and Elimination\u003cbr\u003e Toxicogenomics: Integration of New Molecular Biological Tools in Toxicology\u003cbr\u003e","brand":"Wiley-VCH Verlag GmbH","offers":[{"title":"Default Title","offer_id":53196944998743,"sku":"9783527304318","price":184.46,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/molecular-biology-in-medicinal-chemistry-9783527304318","provider":"Book Curl","version":"1.0","type":"link"}