{"product_id":"molecular-and-biochemical-toxicology-9781119042419","title":"Molecular and Biochemical Toxicology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses.\u003cbr\u003e\u003cbr\u003e Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies\u003cbr\u003e Uses a didactic approach with basic biological or theoretical background for the methodology presented\u003cbr\u003e Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology\u003cbr\u003e Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts\u003cbr\u003e A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses  BTS Newsletter review of the \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface xxix\u003c\/p\u003e \u003cp\u003eList of Contributors xxxi\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 1 Introduction 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Molecular and Biochemical Toxicology: Definition and Scope 3\u003cbr\u003e \u003ci\u003eErnest Hodgson and Robert C. Smart\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 2 Techniques in Biochemical and Molecular Toxicology 11\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2 Molecular Techniques for the Study of Gene Function 13\u003cbr\u003e \u003ci\u003eYoshiaki Tsuji and Robert C. Smart\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Transcriptomics 55\u003cbr\u003e \u003ci\u003eB. Alex Merrick\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Proteomics 91\u003cbr\u003e \u003ci\u003eMichael S. Bereman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Metabolomics 115\u003cbr\u003e \u003ci\u003eSusan C. J. Sumner, Wimal Pathmasiri, James E. Carlson, Susan L. McRitchie, and Timothy R. Fennell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Cellular Techniques 135\u003cbr\u003e \u003ci\u003eSharon A. Meyer and Barbara A. Wetmore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Basic Concepts of Molecular Epidemiological Research Methods 159\u003cbr\u003e \u003ci\u003eCathrine Hoyo, David A. Skaar, and Randy L. Jirtle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 3 Mechanisms in Molecular and Biochemical Toxicology 187\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8 Phase I and Phase II Metabolism and Metabolic Interactions: A Summary 189\u003cbr\u003e \u003ci\u003eErnest Hodgson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Structure, Mechanism, and Regulation of Cytochromes P 450 209\u003cbr\u003e \u003ci\u003eJohn M. Seubert, Matthew L. Edin, and Darryl C. Zeldin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Polymorphisms in Phase I and Phase II Genes and Outcomes 239\u003cbr\u003e \u003ci\u003eYoshiaki Tsuji, Edward L. Croom, and Ernest Hodgson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Cellular Transport and Elimination 273\u003cbr\u003e \u003ci\u003eDavid S. Miller and Ronald E. Cannon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Nuclear Receptors 293\u003cbr\u003e \u003ci\u003eSeth W. Kullman, William S. Baldwin, and Gerald A. LeBlanc\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Mechanisms of Cell Death 327\u003cbr\u003e \u003ci\u003eMac Law and Susan Elmore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Mitochondrial Dysfunction 371\u003cbr\u003e \u003ci\u003eJun Ninomiya‐Tsuji\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Reactive Metabolites, Reactive Oxygen Species (ROS), and Toxicity 391\u003cbr\u003e \u003ci\u003eElizabeth L. MacKenzie and Yoshiaki Tsuji\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 DNA Damage and Mutagenesis 421\u003cbr\u003e \u003ci\u003eZhigang Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 DNA Repair 485\u003cbr\u003e \u003ci\u003eIsabel Mellon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Carcinogenesis 535\u003cbr\u003e \u003ci\u003eRobert C. Smart and Jonathan R. Hall\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 4 Molecular and Biochemical Aspects of Organ Toxicology 589\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19 Molecular Mechanisms of Respiratory Toxicity 591\u003cbr\u003e \u003ci\u003eJames C. Bonner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Molecular Mechanisms of Hepatotoxicity 629\u003cbr\u003e \u003ci\u003eSupriya R. Kulkarni, Andrew D. Wallace, Sharon A. Meyer, and Angela L. Slitt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Molecular Mechanisms of Renal Toxicology 665\u003cbr\u003e \u003ci\u003eLawrence H. Lash\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Molecular Mechanisms of Neurotoxicity 709\u003cbr\u003e \u003ci\u003eKimberly P. Keil, Marianna Stamou, and Pamela J. Lein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 Molecular Mechanisms of Immunotoxicity 773\u003cbr\u003e \u003ci\u003eTai L. Guo, Joella Xu, Yingjia Chen, Daniel E. Lefever, Guannan Huang, and David A. Lawrence\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Molecular Mechanisms of Reproductive Toxicity 823\u003cbr\u003e \u003ci\u003eAyelet Ziv‐Gal, Catheryne Chiang, and Jodi Anne Flaws\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 Molecular Mechanisms of Developmental Toxicity 851\u003cbr\u003e \u003ci\u003eAntonio Planchart\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection 5 Emerging Areas in Molecular and Biochemical Toxicology 877\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e26 Computational and Molecular Approaches to Risk Assessment 879\u003cbr\u003e \u003ci\u003eRichard S. Judson, John Wambaugh, Kristin Isaacs, and Russell S. Thomas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Nanotoxicology 909\u003cbr\u003e \u003ci\u003eJames C. Bonner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Developmental Origins of Health and Disease 933\u003cbr\u003e \u003ci\u003eMichael Cowley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Exposome 945\u003cbr\u003e \u003ci\u003eStephen M. Rappaport\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 969\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49406971904343,"sku":"9781119042419","price":134.06,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/molecular-and-biochemical-toxicology-9781119042419","provider":"Book Curl","version":"1.0","type":"link"}