{"product_id":"mitochondrial-medicine-9781071612729","title":"Mitochondrial Medicine","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine. Volume III guides readers through chapters on intercellular mitochondrial transfer, Cytoplasmic transfer methods, Ndufs4 knockout mouse, in vivo assessment of mitochondrial oxygen consumption, mitochondrial network analysis by imaging, mitochondrial respiration in platelets, Heterologous Inferential Analysis (HIA), bioenergetic profiling, integrative methods for studying cardiac energetics, and isolation and deep sequencing of mitochondrial DNA.Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls.   Authoritative and accessible,Mitochondrial Medicine, Second Edition, Volume 3: Manipulating Mitochondria and Disease- Speci\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e1. Allotopic Expression of ATP6 in the Mouse as a Transgenic Model of Mitochondrial Disease\u003c\/p\u003e  \u003cp\u003eDavid A. Dunn and  Carl A. Pinkert \u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e2. Mitochondrial Transplantation for Ischemia Reperfusion Injury\u003c\/p\u003e  \u003cp\u003eIlias P. Doulamis and James D. McCully\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e3. Quantitatively Controlled Intercellular Mitochondrial Transfer by Cell Fusion-Based Method Using a Microfluidic Device\u003c\/p\u003e  \u003cp\u003eKen-Ichi Wada,\u003csup\u003e \u003c\/sup\u003eKazuo Hosokawa, Yoshihiro Ito,\u003csup\u003e \u003c\/sup\u003eand Mizuo Maeda\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e4. Lipophilic Conjugates for Carrier-Free Delivery of RNA Importable Into Human Mitochondria\u003c\/p\u003e  \u003cp\u003eIlya Dovydenko, Mariya Meschaninova, Anne-Marie Heckel, Ivan Tarassov, Alya Venyaminova, and Nina Entelis\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e5. Drug Discovery Assay to Identify Modulators of the Mitochondrial Ca\u003csup\u003e2+\u003c\/sup\u003e Uniporter \u003c\/p\u003e  Daniela M. Arduino, Valerie Goh, Dejana Mokranjac, and Fabiana Perocchi\u003csup\u003e\u003c\/sup\u003e\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e6. Cytoplasmic Transfer Methods for Studying the Segregation of Mitochondrial DNA in Mice\u003c\/p\u003e  \u003cp\u003eThomas Kolbe, Ralf Steinborn, and Joerg P. Burgstaller\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e7. Electron Attachment to Isolated Molecules as a Probe To Understand Mitochondrial Reductive Processes\u003c\/p\u003e  Stanislav A. Pshenichnyuk\u003csup\u003e \u003c\/sup\u003eand Alberto Modelli\u003csup\u003e\u003c\/sup\u003e\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e8. Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation\u003c\/p\u003e  \u003cp\u003eMatthias Hecker, Natascha Sommer, and Konstantin Mayer\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  9. Assessment of the Effects of Drugs on Mitochondrial Respiration\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eJana Hroudová and Zdeněk Fišar\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  10. The Ndufs4 Knockout Mouse: A Dual Threat Model of Childhood Mitochondrial Disease and Normative Aging\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eAnthony S. Grillo, Alessandro Bitto, and Matt Kaeberlein\u003c\/p\u003e    11. Suborganellar Localisation of Mitochondrial Proteins and Transcripts in Human Cells  \u003cp\u003eAnna Smirnova, Ludovic Richert, Alexandre Smirnov, Yves Mély, and Ivan Tarassov\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e12. In vivo Assessment of Mitochondrial Oxygen Consumption\u003c\/p\u003e  \u003cp\u003eFloor A. Harms and Egbert G. Mik\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  13. Update of Mitochondrial Network Analysis by Imaging: Proof of Technique in Schizophrenia \u003cp\u003e\u003c\/p\u003e  \u003cp\u003eYekaterina Yatchenko and Dorit Ben-Shachar\u003c\/p\u003e  14. Heterologous Inferential Analysis (HIA) and other Emerging Concepts\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eIn Understanding Mitochondrial Variation in Pathogenesis: There is no More Low Hanging Fruit\u003c\/p\u003e  Antón Vila-Sanjurjo, Paul M. Smith, and Joanna L. Elson\u003ci\u003e\u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e15. Accurate Measurement of Cellular and Cell-Free Circulating Mitochondrial DNA Content from Human Blood Samples Using Real Time Quantitative PCR\u003c\/p\u003e  \u003cp\u003eHannah Rosa and Afshan Malik\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e16. Measurement of Mitochondrial Respiration in Platelets\u003c\/p\u003e  \u003cp\u003eZdeněk Fišar and Jana Hroudová\u003c\/p\u003e    17. Isolation and Electron Microscopic Analysis of Liver Cancer Cell Mitochondria \u003cp\u003eYaschar Kabiri, Carola Eberhagen, Sabine Schmitt, Percy A. Knolle, and Hans Zischka\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  18. Assessment of Mitochondrial Reactive Oxygen Species and Redox Regulation in Stem Cells\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eMadhavee Thumiah-Mootoo, Tina Podinic, and Mireille Khacho\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  19. Single Cell Approaches for Studying the Role of Mitochondrial DNA in Neurodegenerative Disease\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eLaura J. Bailey, Joanna L. Elson, and Ilse S. Pienaar\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e20. A New Method for Sequencing the Mitochondrial Genome by Using Long Read Technology\u003c\/p\u003e  \u003cp\u003eSophie Dhorne-Pollet, Nicolas Pollet, and Eric Barrey\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e21. Mitochondrial DNA as a Sensitive Biomarker of UV-induced Cellular Damage in Human Skin\u003c\/p\u003e  \u003cp\u003eAmy Bowman and Mark A. Birch-Machin\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e22. Isolation of Mitochondria-associated ER Membranes (MAMs), Synaptic MAMs and Glycosphingolipid Enriched Microdomains (GEMs) from Brain Tissues and Neuronal Cells\u003c\/p\u003e  \u003cp\u003eIda Annunziata, Jason Andrew Weesner, and Alessandra d’Azzo\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e23. Mitochondrial Diagnostics: A Discovery-Based Biochemical Platform for Phenotyping Human Peripheral Blood Cell Mitochondria\u003c\/p\u003e  \u003cp\u003eMargaret A. M. Nelson\u003csup\u003e \u003c\/sup\u003eand Kelsey H. Fisher-Wellman\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e24. Bioenergetic Profiling Of Human Pluripotent Stem Cells\u003c\/p\u003e  Gizem Inak-Girrbach, Marie-Thérèse Henke, and Alessandro Prigione\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e25. Integrative Methods for Studying Cardiac Energetics\u003c\/p\u003e  \u003cp\u003ePhilippe Diolez, Véronique Deschodt-Arsac, Guillaume Calmettes, Gilles Gouspillou, Laurent Arsac, Pierre Jais, Michel Haissaguerre, and Pierre dos Santos\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  26. Isolation of Mitochondria from Retinal Pigment Epithelial Cell Cultures and an Application Of High Resolution Respirometric Assay (XF\u003csup\u003ee\u003c\/sup\u003e96 Seahorse assay) \u003cp\u003e\u003c\/p\u003e  \u003cp\u003eMasaaki Ishii, Gyda Beeson, Craig Beeson, and Bärbel Rohrer\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e27. The Isolation and Deep Sequencing of Mitochondrial DNA \u003c\/p\u003e  \u003cp\u003eAlexander G. Bury, Fiona M. Robertson, Angela Pyle, Brendan A. I. Payne, and Gavin Hudson\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e28. Ultrastructure of the Mitochondria-Associated Membranes in Human Tumor Specimens\u003c\/p\u003e  \u003cp\u003eGabriel Arismendi-Morillo\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"Springer-Verlag New York Inc.","offers":[{"title":"Default Title","offer_id":51019366367575,"sku":"9781071612729","price":98.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781071612729.jpg?v=1750780038","url":"https:\/\/bookcurl.com\/products\/mitochondrial-medicine-9781071612729","provider":"Book Curl","version":"1.0","type":"link"}