{"product_id":"methods-and-applications-of-statistics-in-clinical-trials-volume-2-9781118304761","title":"Methods and Applications of Statistics in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eMethods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods\u003c\/i\u003e includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features:\u003c\/p\u003e \u003cp\u003e Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems\u003c\/p\u003e \u003cp\u003e Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index\u003c\/p\u003e \u003cp\u003e Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planni\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e“This book provides a good overview on most relevant topics for clinical trials.”  (\u003ci\u003eBiometrical Journal\u003c\/i\u003e, 1 October 2015)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eContributors xix \u003cp\u003ePreface xxiii\u003c\/p\u003e \u003cp\u003e1 Analysis of Over- and Underdispersed Data 1\u003c\/p\u003e \u003cp\u003e2 Analysis of Variance (ANOVA) 10\u003c\/p\u003e \u003cp\u003e3 Assessment of Health-Related Quality of Life 26\u003c\/p\u003e \u003cp\u003e4 Bandit Processes and Response-Adaptive Clinical Trials: The Art of Exploration Versus Exploitation 40\u003c\/p\u003e \u003cp\u003e5 Bayesian Dose-Finding Designs in Healthy Volunteers 51\u003c\/p\u003e \u003cp\u003e6 Bootstrap 62\u003c\/p\u003e \u003cp\u003e7 Conditional Power in Clinical Trial Monitoring 102\u003c\/p\u003e \u003cp\u003e8 Cost-Effectiveness Analysis 111\u003c\/p\u003e \u003cp\u003e9 Cox-Type Proportional Hazards Models 126\u003c\/p\u003e \u003cp\u003e10 Empirical Likelihood Methods in Clinical Experiments 146\u003c\/p\u003e \u003cp\u003e11 Frailty Models 166\u003c\/p\u003e \u003cp\u003e12 Futility Analysis 174\u003c\/p\u003e \u003cp\u003e13 Imaging Science in Medicine I: Overview 187\u003c\/p\u003e \u003cp\u003e14 Imaging Science in Medicine, II: Basics of X-Ray Imaging 213\u003c\/p\u003e \u003cp\u003e15 Imaging Science in Medicine, III: Digital (21st Century) X-Ray Imaging 264\u003c\/p\u003e \u003cp\u003e16 Intention-to-Treat Analysis 313\u003c\/p\u003e \u003cp\u003e17 Interim Analyses 323\u003c\/p\u003e \u003cp\u003e18 Interrater Reliability 334\u003c\/p\u003e \u003cp\u003e19 Intrarater Reliability 340\u003c\/p\u003e \u003cp\u003e20 Kaplan-Meier Plot 357\u003c\/p\u003e \u003cp\u003e21 Logistic Regression 365\u003c\/p\u003e \u003cp\u003e22 Metadata 380\u003c\/p\u003e \u003cp\u003e23 Microarray 392\u003c\/p\u003e \u003cp\u003e24 Multi-Armed Bandits, Gittins Index, and Its Calculation 416\u003c\/p\u003e \u003cp\u003e25 Multiple Comparisons 436\u003c\/p\u003e \u003cp\u003e26 Multiple Evaluators 446\u003c\/p\u003e \u003cp\u003e27 Noncompartmental Analysis 457\u003c\/p\u003e \u003cp\u003e28 Nonparametric ROC Analysis for Diagnostic Trials 483\u003c\/p\u003e \u003cp\u003e29 Optimal Biological Dose for Molecularly Targeted Therapies 496\u003c\/p\u003e \u003cp\u003e30 Over- and Underdispersion Models 506\u003c\/p\u003e \u003cp\u003e31 Permutation Tests in Clinical Trials 527\u003c\/p\u003e \u003cp\u003e32 Pharmacoepidemiology, Overview 536\u003c\/p\u003e \u003cp\u003e33 Population Pharmacokinetic and Pharmacodynamic Methods 551\u003c\/p\u003e \u003cp\u003e34 Proportions: Inferences and Comparisons 570\u003c\/p\u003e \u003cp\u003e35 Publication Bias 595\u003c\/p\u003e \u003cp\u003e36 Quality of Life 608\u003c\/p\u003e \u003cp\u003e37 Relative Risk Modeing 622\u003c\/p\u003e \u003cp\u003e38 Sample Size Considerations for Morbidity\/Mortality Trials 633\u003c\/p\u003e \u003cp\u003e39 Sample Size for Comparing Means 642\u003c\/p\u003e \u003cp\u003e40 Sample Size for Comparing Proportions 653\u003c\/p\u003e \u003cp\u003e41 Sample Size for Comparing Time-to-Event Data 664\u003c\/p\u003e \u003cp\u003e42 Sample Size for Comparing Variabilities 672\u003c\/p\u003e \u003cp\u003e43 Screening, Models of 689\u003c\/p\u003e \u003cp\u003e44 Screening Trials 721\u003c\/p\u003e \u003cp\u003e45 Secondary Efficacy End Points 731\u003c\/p\u003e \u003cp\u003e46 Sensitivity, Specificity, and Receiver Operator Characteristic (ROC) Methods 740\u003c\/p\u003e \u003cp\u003e47 Software for Genetics\/Genomics 752\u003c\/p\u003e \u003cp\u003e48 Stability Study Designs 778\u003c\/p\u003e \u003cp\u003e49 Subgroup Analysis 793\u003c\/p\u003e \u003cp\u003e50 Survival Analysis, Overview 802\u003c\/p\u003e \u003cp\u003e51 The FDA and Regulatory Issues 815\u003c\/p\u003e \u003cp\u003e52 The Kappa Index 836\u003c\/p\u003e \u003cp\u003e53 Treatment Interruption 846\u003c\/p\u003e \u003cp\u003e54 Trial Reports: Improving Reporting, Minimizing Bias, and Producing Better Evidence-Based Practice 860\u003c\/p\u003e \u003cp\u003e55 U.S. Department of Veterans Affairs Cooperative Studies Program 876\u003c\/p\u003e \u003cp\u003e56 Women's Health Initiative: Statistical Aspects and Selected Early Results 901\u003c\/p\u003e \u003cp\u003e57 World Health Organization (WHO): Global Health Situation 914\u003c\/p\u003e \u003cp\u003eIndex 925\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":48866368389463,"sku":"9781118304761","price":157.45,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781118304761.jpg?v=1722278315","url":"https:\/\/bookcurl.com\/products\/methods-and-applications-of-statistics-in-clinical-trials-volume-2-9781118304761","provider":"Book Curl","version":"1.0","type":"link"}