{"product_id":"hepatocellular-carcinoma-diagnosis-and-treatment-9783319342122","title":"Hepatocellular Carcinoma: Diagnosis and Treatment","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e•\tHepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists. \u003cbr\u003e\u003cbr\u003e\"This is a well written text and should be a good reference book for those who see patients with HCC..\" - Practical Gastroenterology\u003cbr\u003e\u003cbr\u003e\"...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC.\" - Digestive and Liver Disease\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart A. Causes, Biological and Molecular bases of HCC\u003cbr\u003eChapter 1. Epidemiology of Hepatocellular Carcinoma - Donna L. White, Fasiha Kanwal, Li Jiao and Hashem B. El-Serag\u003cbr\u003eChapter 2. Environmental Carcinogens and Risk for Human Liver Cancer - John D. Groopman\u003cbr\u003eChapter 3. Molecular Mechanisms of Hepatocellular Carcinoma - Hani Alotaibi, Nese Atabey, Kasım Diril, Esra Erdal and Mehmet Ozturk\u003cbr\u003eChapter 4. Chemically-Induced Hepatocarcinogenesis - Yvonne P. Dragan\u003cbr\u003eChapter 5. Molecular Profiling of Human Hepatocellular Carcinoma - Anuradha Budhu and Xin Wei Wang\u003cbr\u003eChapter 6. Genomic signatures of risk factors and molecular identification of HCC subtypes - Jean-Charles Nault and Jessica Zucman-Rossi \u003cbr\u003eChapter 7. MicroRNAs and hepatocellular carcinoma - Aldo Cavallini\u003cbr\u003eChapter 8. Non-tumor prognostic factors in hepatocellular carcinoma - Nicolas Goossens, Ismail Labgaa and Augusto Villanueva         \u003cbr\u003eChapter 9. Gut microbiota and HCC - Sven H. Loosen, Christoph Roderburg and Tom Luedde\u003cbr\u003eChapter 10. Hepatocellular Carcinoma as a Paradigm for a Systemic Evolutionary Approach to Cancer - Antonio Mazzocca, Giovanni Ferraro, Giovanni Misciagna and Brian I. Carr\u003cbr\u003eChapter 11. HCC and its Microenvironment - Brian I. Carr\u003cbr\u003eChapter 12. Circulating tumor cells (Liquid Tumor Biopsy) in hepatocellular carcinoma: biology, methodologies, and clinical implications - Zhengfen Yin\u003cbr\u003eChapter 13.  Role of the immune system in hepatocellular carcinoma: Implications for existing and novel therapies - Tobias Flecken and Robert Thimme\u003cbr\u003eChapter 14. Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma - Evgeny V. Denisov, Tatiana S. Gerashchenko, Marina V. Zavyalova, Vasiliy N. Manskikh, Evgeny L. Choinzonov, Nadezhda V. Cherdyntseva and Vladimir M. Perelmuter\tChapter 15. Systemic inflammation: a new prognostic domain and source of therapeutic targets in hepatocellular carcinoma - David J. Pinato and Rohini Sharma\u003cbr\u003eChapter 16. Hepatocellular Carcinoma Associated with Hepatitis B virus - Inbal Houri and Oren Shibolet\u003cbr\u003e\u003cbr\u003eChapter 18. Obesity, NASH and HCC - Chadia L. Robertson, Devanand Sarkar and Arun J. Sanyal\u003cbr\u003eChapter 19. Metabolic Disease and Hepatocellular Carcinoma - David H. Van Thiel, Salamah Mohammad Alwahsh and Giuliano Ramadori\u003cbr\u003ePart B. Diagnosis\u003cchapter pathologic aspects of hepatocellular tumors michael a. nalesnik\u003e\u003c\/chapter\u003eChapter 21. Protein biomarkers in the management of hepatocellular carcinoma: Novel combinatory approaches - Philip Johnson and Sarah Berhane\u003cbr\u003eChapter 22. Surveillance for hepatocellular carcinoma - Cristina Della Corte and Massimo Colombo\u003cbr\u003eChapter 23. Use of Imaging Techniques to Screen for Hepatocellular Carcinoma - Satoshi Goshima\u003cbr\u003eChapter 24. Ultrasound of Hepatocellular Carcinoma: The Important Contribution of Contrast Enhancement - Tae Kyoung Kim, Hyun-Jung Jang and Stephanie R. Wilson\u003cbr\u003eChapter 25. MRI for Detection and Evaluation of Hepatocellular Carcinoma - Anuj Patel, Neil Malhotra, Christopher G. Roth, Sandeep Deshmukh and Donald G. Mitchell\u003cbr\u003eChapter 26. Computed Tomography of HCC - Francesco Agnello and Giuseppe Brancatelli\u003cbr\u003eChapter 27. Clinical features and clinician's diagnostic approach to hepatocellular carcinoma - Tamar Thurm and Oren Shibolet\u003cbr\u003eChapter 28. Current HCC Staging systems: their uses and limitations - Yukio Tokumitsu and Hiroaki Nagano\u003cbr\u003ePart C. Therapies\u003cbr\u003eChapter 29. Percutaneous Ethanol Injection - Tito Livraghi, Maria Franca Meloni and Anita Andreano\u003cbr\u003eChapter 30. Thermal Ablative Treatments For Hepatocellular Carcinoma - Antonio Facciorusso and Michele Barone\u003cbr\u003eChapter 31. Resection of Hepatocellular Carcinoma - Nir Lubezky, Yaacov Goykhman, Richard Nakache and Ido Nachmany               Chapter 32. Liver Transplantation for Hepatocellular Carcinoma - Georg Györi, Pierre-Alain Clavien and Mickaël Lesurtel\u003cbr\u003eChapter 33. Medical Therapy of HCC - Brian I. Carr, Srikanth Nagalla and Ravit Geva             \u003cbr\u003eChapter 34. Targeted therapies for Hepatocellular Carcinoma - Susan Kralian and Brian I. Carr\u003cbr\u003eChapter 35. Radiation Therapy for Hepatocellular Carcinoma - Andrew S. Kennedy       \u003cbr\u003eChapter 36. Psychosocial Issues in Hepatocellular carcinoma - Jennifer L. Steel, Feridey N. Carr, Alexandra Savkova, Naadia Ahmed, Andrea DiMartini and Mary A. Dew\u003cbr\u003eChapter 37. Bringing it all together - Brian I. Carr\u003cbr\u003e","brand":"Springer International Publishing AG","offers":[{"title":"Default Title","offer_id":53195636048215,"sku":"9783319342122","price":123.49,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/hepatocellular-carcinoma-diagnosis-and-treatment-9783319342122","provider":"Book Curl","version":"1.0","type":"link"}