{"product_id":"genotoxicity-assessment-methods-and-protocols-2031-methods-in-molecular-biology-9781493996452","title":"Genotoxicity Assessment Methods and Protocols","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis current edition explores new tests for genotoxicity testing, along with other well-known techniques. This will further help in our understanding of the genotoxic effects of chemicals. The book has different sections dealing with various assays for gene mutation, chromosomal abnormalities, primary DNA damage, etc. It also delves into plant models, animals and their alternates, as well as \u003ci\u003ein silico \u003c\/i\u003eapproaches for genetic toxicology. Written for the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, tips on troubleshooting and avoiding known pitfalls. \u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003eAuthoritative and up-to-date, \u003ci\u003eGenotoxicity Assessment: Methods and Protocols, Second Edition\u003c\/i\u003e serves as a highly useful and ready resource for research students and scientists working in regulatory toxicology as well as biomedical, biochemical, and pharmaceutical sciences.\u003c\/div\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003ePart I: Gene Mutation Assays\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e1. In Vitro Mouse Lymphoma Cell (L5178Y \u003ci\u003eTk\u003c\/i\u003e\u003csup\u003e+\/- \u003c\/sup\u003e-3.7.2.C) Forward Mutation Assay\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Melissa R. Schisler, Martha M. Moore, and B. Bhaskar Gollapudi\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e2. Erythrocyte-Based \u003ci\u003ePig-a\u003c\/i\u003e Gene Mutation Assay\u003c\/p\u003e  \u003cp\u003e            Jeffrey C. Bemis, Nikki E. Hall, and Stephen D. Dertinger\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e3. Detection of In Vivo Mutation in the \u003ci\u003eHprt\u003c\/i\u003e and \u003ci\u003ePig-a\u003c\/i\u003e Genes of Rat Lymphocytes\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Vasily N. Dobrovolsky, Joseph G. Shaddock, Roberta A. Mittelstaedt, Daishiro Miura, and Robert H. Heflich\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003ePart II: Assays for Chromosomal Abnormalities\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e4. In Vitro Cytogenetic Assays: Chromosomal Aberrations and Micronucleus Tests\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Pasquale Mosesso and Serena Cinelli\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e5. Dicentric Chromosome Assay (DCA) and Cytokinesis-Block Micronucleus (CBMN) Assay in the Field of Biological Dosimetry\u003c\/p\u003e  \u003cp\u003e            Antonella Testa, Valentina Palma, and Clarice Patrono\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e6. Chromosomal Aberration Test in Human Lymphocytes\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Christian Johannes and Guenter Obe\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e7. In Vivo Micronucleus Assay in Mouse Bone Marrow\u003c\/p\u003e  \u003cp\u003e            Abhishek Kumar Jain and Alok Kumar Pandey\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e8. Micronucleus Cytome Assays in Human Lymphocytes and Buccal Cells\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Claudia Bolognesi and Michael Fenech\u003c\/p\u003e     \u003cp\u003e\u003cb\u003e9. Micronucleus Analysis by Flow Cytometry\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Azeddine Elhajouji and Pascal Stadelmann\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e10. Hen’s Egg Test for Micronucleus Induction (HET-MN)\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Kerstin Reisinger, Eva Dony, Thorsten Wolf, and Katrin Maul\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e11. Comparative Genomic Hybridization (CGH) in Genotoxicology\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Adi Baumgartner, Veronika Hartleb, and Jim D. Taylor\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003ePart III: Tests for Primary DNA Damage\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e12. The Comet Assay: Assessment of In Vitro\u003ci\u003e \u003c\/i\u003eand In Vivo DNA Damage\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Mahima Bajpayee, Ashutosh Kumar, and Alok Dhawan\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e13. The Comet Assay in Human Biomonitoring\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Diana Anderson and Julian Laubenthal\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e14. The Comet Assay in Marine Animals\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Patrizia Guidi, Brett P. Lyons, and Giada Frenzilli\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e15. \u003c\/b\u003e\u003cb\u003eMulticolour Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Julian Laubenthal, Michal R. Gdula, Alok Dhawan, and Diana Anderson\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e16. Detection of DNA Double Strand Breaks Using Pulse Field Gel Electrophoresis\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Vyom Sharma and Vishwa Mohan\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e17. Detection of UV-Induced Thymine Dimers\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Vipin Kumar Yadav, Poorwa Awasthi, and Amit Kumar\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003ePart IV: Assays in Plants and Alternate Animal Models\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e18. Micronucleus Assay with Tetrad Cells of \u003ci\u003eTradescantia\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Miroslav Mišík, Clemens Pichler, Bernhard Rainer, Armen Nersesyan, Katarina Mišíková, and Siegfried Knasmueller\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003e19. \u003c\/b\u003e\u003cb\u003eThe Wing-Spot and the Comet Tests as Useful Assays for Detecting Genotoxicity in Drosophila\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Ricard Marcos and Erico R. Carmona\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e\u003cb\u003ePart V: \u003ci\u003eIn Silico\u003c\/i\u003e Testing for Genetic Toxicology\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e\u003cb\u003e20. In Silico Approaches in Predictive Genetic Toxicology\u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003e            Meetali Sinha, Alok Dhawan, and Ramkrishnan Parthasarathi\u003c\/p\u003e","brand":"Humana Press Inc.","offers":[{"title":"Default Title","offer_id":48739727835479,"sku":"9781493996452","price":112.49,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bookcurl.com\/products\/genotoxicity-assessment-methods-and-protocols-2031-methods-in-molecular-biology-9781493996452","provider":"Book Curl","version":"1.0","type":"link"}