{"product_id":"genetic-epidemiology-9781493978670","title":"Genetic Epidemiology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eThis volume details fast-moving research while providing in-depth descriptions of methods and analytical approaches that are helping to understand the genome and how it is related to complex diseases. Chapters guide the reader through common and rare variation, gene-gene and gene-environment interactions and state-of-the-art approaches for the synthesis of genome-wide and gene expression data. Novel approaches for associations in the HLA region, family-based designs, Mendelian Randomization and Copy Number Variation are also presented.  The volume concludes with the challenges researchers face while moving from identifying variants to their functional role and potential drug targets. Written in the highly successful \u003ci\u003eMethods in Molecular Biology\u003c\/i\u003e series format, chapters include introductions to their respective topics, a thorough presentation of methods and approaches and tips on troubleshooting and avoiding known pitfalls.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e1. Introduction to Epidemiological Studies \u003c\/p\u003e  \u003cp\u003eLazaros Belbasis\u003csup\u003e \u003c\/sup\u003eand Vanesa Bellou\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e2. Key Concepts in Genetic Epidemiology\u003c\/p\u003e  \u003cp\u003eKalliope Panoutsopoulou and Eleanor Wheeler\u003c\/p\u003e   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e3. Quality Control of Common and Rare Variants\u003c\/p\u003e  \u003cp\u003eKalliope Panoutsopoulou\u003csup\u003e \u003c\/sup\u003eand Klaudia Walter\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e4. Genome Wide Association Studies\u003c\/p\u003e  \u003cp\u003eAbbas Dehghan\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e5. Assessing Rare Variation in Complex Traits\u003c\/p\u003e  \u003cp\u003eKaroline Kuchenbaecker and Emil Vincent Rosenbaum Appel\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e6. Meta-analysis of Common and Rare Variants\u003c\/p\u003e  \u003cp\u003eKyriaki Michailidou\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e7. Gene-gene and Gene-environment Interactions\u003c\/p\u003e  \u003cp\u003eAndrew T. DeWan\u003c\/p\u003e   \u003cp\u003e\u003c\/p\u003e  \u003cp\u003e8. Genetic Association in the HLA Region\u003c\/p\u003e  \u003cp\u003eLoukas Moutsianas and Javier Gutierrez-Achury\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  9. Novel Methods for Family-based Genetic Studies\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eQi Yan\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e10. Methods for Polygenic Traits\u003c\/p\u003e  \u003cp\u003eRaha Pazoki\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e11. Multivariate Methods for Meta-analysis of Genetic Association Studies\u003c\/p\u003e  \u003cp\u003eNiki L. Dimou, Katerina G. Pantavou, Georgia G. Braliou, and Pantelis G. Bagos\u003c\/p\u003e    12. Methods of Analysis and Meta-Analysis for Identifying Differentially Expressed Genes  \u003cp\u003ePanagiota I Kontou, Athanasia Pavlopoulou, and Pantelis G. Bagos\u003csup\u003e\u003c\/sup\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e13. A Primer in Mendelian Randomization Methodology with a Focus on Utilizing Published Summary Association Data\u003c\/p\u003e  \u003cp\u003eNiki L. Dimou and Konstantinos K. Tsilidis\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  14. Copy Number Variation\u003cp\u003e\u003c\/p\u003e  \u003cp\u003eAurélien Macé, Zoltán Kutalik, and Armand Valsesia\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e15. From Identification to Function: Current Strategies to Prioritise and Follow-Up GWAS Results\u003c\/p\u003e  Antonio J Berlanga-Taylor\u003cp\u003e\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e  \u003cp\u003e16. Translating Human Genetics into Novel Drug Targets\u003c\/p\u003e  \u003cp\u003eKarol Estrada\u003c\/p\u003e  \u003cp\u003e \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"Humana Press Inc.","offers":[{"title":"Default Title","offer_id":48739726000471,"sku":"9781493978670","price":161.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781493978670.jpg?v=1720053006","url":"https:\/\/bookcurl.com\/products\/genetic-epidemiology-9781493978670","provider":"Book Curl","version":"1.0","type":"link"}