{"product_id":"g-proteincoupled-receptors-in-drug-discovery-4-drug-discovery-series-9780824725730","title":"G ProteinCoupled Receptors in Drug Discovery 4","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eThe broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, \u003cb\u003eG Protein-Coupled Receptors in Drug Discovery\u003c\/b\u003e describes the physiological roles of GPCRs and their involvement in various human diseases.\u003c\/p\u003e\u003cp\u003eThe book presents current approaches in drug discovery that include target selection, establishment of screening and functional assays. It also covers recombinant GPCR expression for drug screening and structural biology, different methods for structural characterization of GPCRs, and the importance of bioinformatics. The book has been carefully edited to avoid overlapping information, some duplication has been intentionally permitted so that each chapter can function as an independent unit. Providing in-depth discussions on structure and dynamics of GPCRs, this book outlines the importance of the GPCRs to drug discovery in general and drug targets specifically.\u003c\/p\u003e\u003cp\u003eDaniel E. Levy, editor of the \u003cem\u003eDrug Discovery Series\u003c\/em\u003e, is the founder of \u003ca href=\"http:\/\/www.delbiopharma.com\/\"\u003eDEL BioPharma\u003c\/a\u003e, a consulting service for drug discovery programs. He also maintains a \u003ca href=\"http:\/\/organicchemistry-educationandindustry.blogspot.com\/\"\u003eblog\u003c\/a\u003e that explores organic chemistry.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction. G Protein-Coupled Receptors as Targets for Drug Discovery. G Protein-Coupled Receptors in Cardiovascular Diseases. G Protein-Coupled Receptors in Cancer. G Protein-Coupled Receptors in Metabolic Disease. G Protein- Coupled Receptors in CNS Drug Discovery. Recombinant G Protein-Coupled Receptors for Drug Discovery. High Throughput Screening Assays for G Protein-Coupled Receptors. Bioinformatics\/ Molecular Modelling of G Protein-Coupled Receptors. Structure and Dynamics of G Protein-Coupled Receptors. Toward Crystallization of G Protein-Coupled Receptors. Novel Solid-State NMR Methods for Structural Studies on G Protein-Coupled Receptors. Structural Genomics Initiatives on G Protein-Coupled Receptors. Dimerization of G Protein-Coupled Receptors. Orphan G Protein-Coupled Receptors.","brand":"Taylor \u0026 Francis Inc","offers":[{"title":"Default Title","offer_id":49406176035159,"sku":"9780824725730","price":175.75,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780824725730.jpg?v=1730494794","url":"https:\/\/bookcurl.com\/products\/g-proteincoupled-receptors-in-drug-discovery-4-drug-discovery-series-9780824725730","provider":"Book Curl","version":"1.0","type":"link"}