{"product_id":"experimental-research-methods-in-orthopedics-and-trauma-9783131731111","title":"Experimental Research Methods in Orthopedics and","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003e\u003cem\u003eCovering all state-of-the-art experimental research methods in orthopedic surgery and trauma\u003c\/em\u003e\u003c\/strong\u003e\u003c\/p\u003e \u003cp\u003eFrom bioinformatics to nanotechnology, advances in basic research ultimately drive advances in clinical care. This book provides a comprehensive summary of all current research methodologies for translational and pre-clinical studies in biomechanics and orthopedic trauma surgery. With this \"roadmap\" at hand, specialists and trainees will have the tools to conduct high-quality experimental research in any area of musculoskeletal science, with a solid understanding of how the findings can be applied in patient care. \u003c\/p\u003e \u003cp\u003eSpecial Features:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003eUtilizes the principles and methodology of modern, evidence-based medicine in pre-clinical musculoskeletal research \u003c\/li\u003e\n\u003cli\u003e Offers a comprehensive analysis of in vivo models for studying different components of the musculoskeletal system\u003c\/li\u003e\n\u003cli\u003e Demonstrates how principles of structural, functional, and numerical biomechanics can be utilized in well-defined experimental research studies – spanning topics from fracture fixation to gait analysis to bone remodeling\u003c\/li\u003e\n\u003cli\u003e Covers the role of new macroscopic CT and ultrasound imaging techniques for assessing bone and cartilage function \u003c\/li\u003e\n\u003cli\u003e Explores cutting-edge developments in cell culture research, molecular testing, and tissue engineering \u003c\/li\u003e\n\u003cli\u003e Provides practical advice, a glossary of key terminology, and hundreds of illustrations to familiarize clinicians with every aspect of designing and interpreting an effective research study \u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWith 54 state-of-the-art chapters by orthopedic surgeons, musculoskeletal physicians, biologists, engineers, physicists, and mathematicians, \u003cem\u003eExperimental Research Methods in Orthopedics and Trauma\u003c\/em\u003e is the authoritative reference on the topic. It is essential for clinicians, basic researchers, and orthopedic surgical trainees who need to understand experimental research methodology\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePart 1 Why Do We Need Experimental Research?\u003c\/strong\u003e\u003cbr\u003e 1 Evidence-Based Research\u003cbr\u003e 2 Establishing a Basic Research Facility in Orthopedic Surgery\u003cbr\u003e 3 Good Laboratory Practice and Quality Control\u003cbr\u003e 4 How to Prepare for a Period in Research\u003cbr\u003e \u003cstrong\u003ePart 2 Structural Biomechanics\u003c\/strong\u003e\u003cbr\u003e 5 Physiological Boundary Conditions for Mechanical Testing\u003cbr\u003e 6 Static, Dynamic, and Fatigue Mechanical Testing\u003cbr\u003e 7 Use of Human and Animal Specimens in Biomechanical Testing\u003cbr\u003e 8 Whole Bone Biomechanics\u003cbr\u003e 9 Biomechanics of Trabecular and Cortical Bone\u003cbr\u003e 10 Biomechanics of Fracture Fixation\u003cbr\u003e 11 Biomechanical Assessment of Fracture Repair\u003cbr\u003e 12 Biomechanics of Cartilage\u003cbr\u003e 13 Biomechanics of Joints\u003cbr\u003e 14 Spine Biomechanics\u003cbr\u003e \u003cstrong\u003ePart 3 Functional Biomechanics\u003c\/strong\u003e\u003cbr\u003e 15 Musculokeletal Dynamics\u003cbr\u003e 16 Measurement Techniques\u003cbr\u003e 17 Clinical Assessment of Function\u003cbr\u003e 18 Functional Biomechanics with Cadaver Specimens\u003cbr\u003e \u003cstrong\u003ePart 4 Numerical Biomechanics\u003c\/strong\u003e\u003cbr\u003e 19 Inverse Dynamics\u003cbr\u003e 20 Principles of Finite Elements Analysis\u003cbr\u003e 21 Validation of Finite Element Models\u003cbr\u003e 22 Computational Biomechanics of Bone\u003cbr\u003e 23 Numerical Simulation of Implants and Prosthetic Devices\u003cbr\u003e 24 Numerical Simulation of Fracture Healing and Bone Remodelling\u003cbr\u003e \u003cstrong\u003ePart 5 Imaging\u003c\/strong\u003e\u003cbr\u003e 25 Micro-Computed Tomography Imaging of Bone Tissue\u003cbr\u003e 26 Imaging Bone\u003cbr\u003e 27 Ultrasound Techniques for Imaging Bone\u003cbr\u003e 28 In Vivo Scanning\u003cbr\u003e 29 Imaging of Cartilage Function\u003cbr\u003e 30 Histochemistry Bone and Cartilage\u003cbr\u003e 31 Immunohistochemistry\u003cbr\u003e 32 Molecular Imaging In Situ Hybridization\u003cbr\u003e 33 Laser Scanning Confocal Microscopy and Laser Microdissection\u003cbr\u003e 34 Image Analysis Histomorphometry Stereology\u003cbr\u003e \u003cstrong\u003ePart 6 Cellular Studies\u003c\/strong\u003e\u003cbr\u003e 35 Cell Culture Research\u003cbr\u003e 36 Cartilage Explants and Organ Culture Models\u003cbr\u003e 37 Fluid Flow and Strain in Bone\u003cbr\u003e 38 Biomechanics of Bone Cells\u003cbr\u003e \u003cstrong\u003ePart 7 Molecular Techniques in Bone Repair\u003c\/strong\u003e\u003cbr\u003e 39 Molecular Testing\u003cbr\u003e 40 Genetically Modified Models for Bone Repair\u003cbr\u003e \u003cstrong\u003ePart 8 In Vivo Models\u003c\/strong\u003e\u003cbr\u003e 41 General Considerations for an In Vivo Model\u003cbr\u003e 42 Animal Models for Bone Healing\u003cbr\u003e 43 Models for Impaired Healing\u003cbr\u003e 44 In Vivo Models for Bone and Joint Infections\u003cbr\u003e 45 In Vivo Models for Articular Cartilage Repair\u003cbr\u003e 46 In Vivo Soft Tissue Models\u003cbr\u003e \u003cstrong\u003ePart 9 Tissue Engineering\u003c\/strong\u003e\u003cbr\u003e 47 Scaffolds for Tissue Engineering and Materials for Repair\u003cbr\u003e 48 Use of Growth Factors in Musculoskeletal Research\u003cbr\u003e 49 Stem Cells for Musculoskeletal Repair\u003cbr\u003e 50 Biological Evaluation and Testing of Medical Devices\u003cbr\u003e \u003cstrong\u003ePart 10 Statistics for Experimental Research\u003c\/strong\u003e\u003cbr\u003e 51 Study Design\u003cbr\u003e 52 Power and Sample Size Calculation\u003cbr\u003e 53 Nonparametric versus Parametric Tests\u003cbr\u003e 54 How to Limit Bias in Experimental Research\u003c\/p\u003e","brand":"Thieme Publishing Group","offers":[{"title":"Default Title","offer_id":51138468446551,"sku":"9783131731111","price":84.6,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783131731111.jpg?v=1751919506","url":"https:\/\/bookcurl.com\/products\/experimental-research-methods-in-orthopedics-and-trauma-9783131731111","provider":"Book Curl","version":"1.0","type":"link"}