{"product_id":"essential-guide-to-reading-biomedical-papers-9781119959960","title":"Essential Guide to Reading Biomedical Papers","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eEssential Guide to Reading Biomedical Papers: Recognising and Interpreting Best Practice\u003c\/b\u003e is an indispensable companion to the biomedical literature. This concise, easy-to-follow text gives an insight into core techniques and practices in biomedical research and how, when and why a technique should be used and presented in the literature. Readers are alerted to common failures and misinterpretations that may evade peer review and are equipped with the judgment necessary to be properly critical of the findings claimed by research articles. This unique book will be an invaluable resource for students, technicians and researchers in all areas of biomedicine.\u003c\/p\u003e \u003cp\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAllows the reader to develop the necessary skills to properly evaluate research articles\u003c\/li\u003e \u003cli\u003eCoverage of over 30 commonly-used techniques in the biomedical sciences\u003c\/li\u003e \u003cli\u003eGlobal approach and application, with contributions from leading experts in diverse fields\u003c\/li\u003e \u003c\/ul\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e“The book would be of most benefit to new researchers or early career scientists though with some benefits to the more experienced scientist moving into a new discipline.”  (\u003ci\u003eMicrobiology Today\u003c\/i\u003e, 1 September 2013)\u003c\/p\u003e \u003cp\u003e“As a guide to how to properly ask questions of life and how to interpret its often-enigmatic answers, this book is a must read. Summing Up: Highly recommended. Upper-division undergraduates, graduate students, researchers\/faculty, and professionals.”  (\u003ci\u003eChoice\u003c\/i\u003e, 1 August 2013)\u003c\/p\u003e \u003cp\u003e“Too many recent bioscience graduates lack significant research lab experience. Even research projects can expose them to just a few techniques. Appraisal of research papers in undergraduate courses tends to address the results, but rarely includes a critical evaluation of the researchers methodology. In reality, few bioscientists can claim a working knowledge of more than a handful of the techniques covered in this collection.\u003c\/p\u003e \u003cp\u003eThese shortcomings can be greatly overcome thanks to this book. The contributors are active research scientists of high quality. Each addresses the methods in a critical sense and provide an expert's view of the advantages and pitfalls. There is no equivalent book currently available.” Dr David J. Miller on behalf of The Physiological Society\u003cbr\u003e \u003cbr\u003e “Research questions require the scientist to employ molecular, cell, organism and population approaches, and the reader of scientific literature to carefully consume data from each of those environments.  This book provides a clear and concise summary of the research techniques and approaches that generate data.  Importantly, the authors identify appropriate uses and cautionary caveats, essential for readers who do not use the technique.  This book is essential for accurate and careful interpretation of scientific literature.” Professor Robert G. Carroll, Editor \u003ci\u003eAdvances in Physiology Education\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003eList of contributors ix\u003c\/p\u003e \u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003eAcknowledgements xvii\u003c\/p\u003e \u003cp\u003eIntroduction xix\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection A - Basic principles 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Philosophy of science 3\u003cbr\u003e \u003ci\u003eJames Ladyman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Ingredients of experimental design 9\u003cbr\u003e \u003ci\u003eNick Colegrave\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Statistics: a journey that needs a guide 17\u003cbr\u003e \u003ci\u003eGordon Drummond\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection B - Cell and molecular 27\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4 Organ bath pharmacology 29\u003cbr\u003e \u003ci\u003eEmma Robinson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Small vessel myography 39\u003cbr\u003e \u003ci\u003eTomoko Kamishima and John M Quayle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Mammalian cell cultures: the example of airway epithelial cell cultures for cystic fibrosis research 49\u003cbr\u003e \u003ci\u003eScott H Randell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Electron microscopy (TEM and SEM) 59\u003cbr\u003e \u003ci\u003ePaul Verkade\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Fluorescence microscopy 67\u003cbr\u003e \u003ci\u003eMark Jepson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Intracellular 'sharp' microelectrode recording 77\u003cbr\u003e \u003ci\u003eHelena C Parkington and Harold A Coleman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Single electrode voltage-clamp (SEVC) 85\u003cbr\u003e \u003ci\u003eHarold A Coleman and Helena C Parkington\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Patch clamp recording 95\u003cbr\u003e \u003ci\u003eNeil Bannister and Phil Langton\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Production of antibodies 105\u003cbr\u003e \u003ci\u003eElek Molnar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Immunocytochemistry and immunohistochemistry 117\u003cbr\u003e \u003ci\u003eElek Molnar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Immunoprecipitation (IP) 129\u003cbr\u003e \u003ci\u003eDavid Bates\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Immunoblotting (western) 137\u003cbr\u003e \u003ci\u003eSamantha F. Moore, Joshua S. Savage and Ingeborg Hers\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Applications of green fluorescent protein (GFP) 147\u003cbr\u003e \u003ci\u003eMark Jepson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Fluorescent measurement of ion activity in cells 153\u003cbr\u003e \u003ci\u003eHelen Kennedy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Detection of exocytosis – real time 163\u003cbr\u003e \u003ci\u003eAnja Teschemacher\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Viral vector transgenesis 173\u003cbr\u003e \u003ci\u003eAnja Teschemacher\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Polymerase chain reaction (PCR) and reverse transcription (RT)-PCR 179\u003cbr\u003e \u003ci\u003eLucy F. Donaldson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 \u003ci\u003eIn situ\u003c\/i\u003e hybridisation (ISH) 187\u003cbr\u003e \u003ci\u003eLucy F. Donaldson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Methods of interference (antisense, siRNAs and dominant negative mutations) 193\u003cbr\u003e Allison Fulford\u003c\/p\u003e \u003cp\u003e23 Transcriptome analysis: microarrays 203\u003cbr\u003e \u003ci\u003eCharles Hindmarch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Experimental proteomics 215\u003cbr\u003e \u003ci\u003eThierry Le Bihan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection C - \u003ci\u003eIn vivo\u003c\/i\u003e \/ integrative 229\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e25 Behavioural methodology 231\u003cbr\u003e \u003ci\u003eEmma Robinson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Genetically modified mouse models 241\u003cbr\u003e \u003ci\u003eNina Balthasar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Wireless recording of cardiovascular signals 247\u003cbr\u003e \u003ci\u003eJulian FR Paton and Fiona D McBryde\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Electrical stimulation methods 253\u003cbr\u003e \u003ci\u003eJon Wakerley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Extracellular recording 261\u003cbr\u003e \u003ci\u003eJon Wakerley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Antidromic identification 271\u003cbr\u003e \u003ci\u003eJon Wakerley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Event-triggered averaging, including spike-triggered averaging 279\u003cbr\u003e \u003ci\u003eRichard Apps\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 Axonal transport tracing of CNS pathways 285\u003cbr\u003e \u003ci\u003eJohn Crabtree\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 Cardiovascular methods: general considerations for human studies 291\u003cbr\u003e \u003ci\u003eErica A Wehrwein and Michael J Joyner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Measuring cardiac output in humans 299\u003cbr\u003e \u003ci\u003eErica A Wehrwein and Michael J Joyner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Measuring peripheral blood flow in humans 311\u003cbr\u003e \u003ci\u003eErica A Wehrwein and Michael J Joyner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 319\u003c\/p\u003e","brand":"John Wiley and Sons Ltd","offers":[{"title":"Default Title","offer_id":49528868077911,"sku":"9781119959960","price":110.95,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119959960.jpg?v=1731873340","url":"https:\/\/bookcurl.com\/products\/essential-guide-to-reading-biomedical-papers-9781119959960","provider":"Book Curl","version":"1.0","type":"link"}