{"product_id":"emerging-cancer-therapy-9780470444672","title":"Emerging Cancer Therapy","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eExplores current and emerging applications of microbes as cancer-fighting agents\u003c\/b\u003e  \u003c\/p\u003e\u003cp\u003eWILEY SERIES IN BIOTECHNOLOGY AND BIOENGINEERING \u003ci\u003eAnurag S. Rathore, Series Editor\u003c\/i\u003e  \u003c\/p\u003e\u003cp\u003eToday, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. In recent years, researchers have been working on a new strategy: developing microbes and microbial products that specifically attack cancer cells.  \u003c\/p\u003e\u003cp\u003eThis book breaks new ground in emerging cancer treatment modalities by presenting recent advances in the use of microorganisms and viruses as well as their products in cancer therapy. Seventeen chapters review the application of live microorganisms, high and low molecular weight products derived from microorganisms, and microbial products fused to cancertargeting molecules. In addition, the \u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Live\/Attenuated Bacteria and Viruses as Anticancer Agents 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 \u003ci\u003eSalmonella Typhimurium \u003c\/i\u003eMutants Selected to Grow Only in Tumors to Eradicate Them in Nude Mouse Models 3\u003cbr\u003e\u003ci\u003eRobert M. Hoffman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 The Use of Living \u003ci\u003eListeria Monocytogenes \u003c\/i\u003eas an Active Immunotherapy for the Treatment of Cancer 13\u003cbr\u003e\u003ci\u003eJohn Rothman, Anu Wallecha, Paulo Cesar Maciag, Sandra Rivera, Vafa Shahabi, \u003c\/i\u003eand\u003ci\u003e Yvonne Paterson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Bacillus Calmette–Guerin (BCG) for Urothelial Carcinoma of the Bladder 49\u003cbr\u003e\u003ci\u003eTimothy P. Kresowik \u003c\/i\u003eand\u003ci\u003e Thomas S. Griffith\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Live \u003ci\u003eClostridia\u003c\/i\u003e: A Powerful Tool in Tumor Biotherapy 71\u003cbr\u003e\u003ci\u003eLieve Van Mellaert, Ming Q Wei, \u003c\/i\u003eand\u003ci\u003e Jozef Anné\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 \u003ci\u003eBifi dobacterium \u003c\/i\u003eas a Delivery System of Functional Genes for Cancer Gene Therapy 99\u003cbr\u003e\u003ci\u003eGeng-Feng Fu, Yan Yin, Bi Hu, \u003c\/i\u003eand\u003ci\u003e Gen-Xing Xu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Replication-Selective Viruses for the Treatment of Cancer 119\u003cbr\u003e\u003ci\u003ePadma Sampath \u003c\/i\u003eand\u003ci\u003e Steve H. Thorne\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Engineering Herpes Simplex Virus for Cancer Oncolytic Virotherapy 141\u003cbr\u003e\u003ci\u003eJason S. Buhrman, Tooba A. Cheema, \u003c\/i\u003eand\u003ci\u003e Giulia Fulci\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Bacterial Products as Anticancer Agents 179\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8 Promiscuous Anticancer Drugs from Pathogenic Bacteria: Rational Versus Intelligent Drug Design 181\u003cbr\u003e\u003ci\u003eArsénio M. Fialho \u003c\/i\u003eand\u003ci\u003e Ananda M. Chakrabarty\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Arginine Deiminase and Cancer Therapy 199\u003cbr\u003e\u003ci\u003eLynn Feun, M. Tien Kuo, Ming You, Chung Jing Wu, Medhi Wangpaichitr, \u003c\/i\u003eand\u003ci\u003e Niramol Savaraj\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Cytosine Deaminase\/5-Fluorocytosine Molecular Cancer Chemotherapy 219\u003cbr\u003e\u003ci\u003eSergey A. Kaliberov \u003c\/i\u003eand\u003ci\u003e Donald J. Buchsbaum\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Bacterial Proteins against Metastasis 243\u003cbr\u003e\u003ci\u003eAnna Maria Elisabeth Walenkamp\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 \u003ci\u003ePseudomonas \u003c\/i\u003eExotoxin A-Based Immunotoxins for Targeted Cancer Therapy 269\u003cbr\u003e\u003ci\u003ePhilipp Wolf \u003c\/i\u003eand\u003ci\u003e Ursula Elsässer-Beile\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Denileukin Diftitox in Novel Cancer Therapy 289\u003cbr\u003e\u003ci\u003eLin-Chi Chen \u003c\/i\u003eand\u003ci\u003e Nam H. Dang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 The Application of Cationic Antimicrobial Peptides in Cancer Treatment: Laboratory Investigations and Clinical Potential 309\u003cbr\u003e\u003ci\u003eAshley L. Hilchie \u003c\/i\u003eand\u003ci\u003e David W. Hoskin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Prodiginines and Their Potential Utility as Proapoptotic Anticancer Agents 333\u003cbr\u003e\u003ci\u003eNeil R. Williamson, Suresh Chawrai, Finian J. Leeper, \u003c\/i\u003eand\u003ci\u003e George P.C. Salmond\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Farnesyltransferase Inhibitors of Microbial Origins in Cancer Therapy 367\u003cbr\u003e\u003ci\u003eJingxuan Pan \u003c\/i\u003eand\u003ci\u003e Sai-Ching Jim Yeung\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 The Use of RNA and CpG DNA as Nucleic Acid-Based Therapeutics 379\u003cbr\u003e\u003ci\u003eJörg Vollmer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Patents On Bacteria\/Bacterial Products as Anticancer Agents 403\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18 The Role and Importance of Intellectual Property Generation and Protection in Drug Development 405\u003cbr\u003e\u003ci\u003eArsénio M. Fialho \u003c\/i\u003eand\u003ci\u003e Ananda M. Chakrabarty\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 421\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":53515417190743,"sku":"9780470444672","price":119.65,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/bookcurl.com\/products\/emerging-cancer-therapy-9780470444672","provider":"Book Curl","version":"1.0","type":"link"}