{"product_id":"drug-design-9780854048168","title":"Drug Design","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003ePharmaceutical research draws on increasingly complex techniques to solve the challenges of drug design. Bringing together a number of the latest informatics techniques, this book looks at modelling and bioinformatic strategies; structural genomics and X-ray crystallography; virtual screening; lead optimisation; ADME profiling and vaccine design. A number of relevant case studies, focussing on techniques that have demonstrated their use, will concentrate on G-protein coupled receptors as potential disease targets. Providing details of state-of-the-art research, Drug Design: Cutting Edge Approaches will be invaluable to all drug discovery scientists, including medicinal and combinatorial chemists, molecular modellers, bio- and chemoinformaticians, and pharmacologists, amongst others. University and pharmaceutical company libraries will also benefit from having a copy on their shelves.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"... a book that can be understood by the lay person ... For anyone interested in reading about some individual facets of drug research, ...this book can be recommended.\" * Angewandte Chemie, International Edition, Vol 42, No 22, June 2003, p 2446 *\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eIntroduction; High-Throughput X-Ray Crystallography for Drug Discovery; Bioinformatics in Drug Design: a GPCR case study; Virtual Screening of Virtual Libraries - an Efficient Strategy for Lead Generation; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-like Properties; Mutagenesis and Modelling Highlight the Critical Nature of the TM2-loop-TM3 region of biogenic amine GPCRS; Computational Vaccine Design; Subject Index.","brand":"Royal Society of Chemistry","offers":[{"title":"Default Title","offer_id":51038882922839,"sku":"9780854048168","price":80.75,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780854048168.jpg?v=1750941794","url":"https:\/\/bookcurl.com\/products\/drug-design-9780854048168","provider":"Book Curl","version":"1.0","type":"link"}