{"product_id":"downstream-industrial-biotechnology-9781118131244","title":"Downstream Industrial Biotechnology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eUniversities worldwide are establishing biomanufacturing centers, and demand is growing for a workforce trained in this discipline.   Downstream Recovery and Purification is an affordable, accessible desk reference on biomanufacturing for professionals, instructors, and students.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e“The reference should be valuable to industry professionals as well as to advanced students of biomanufacturing, biochemical engineering, biopharmaceutical facility design, biochemistry, industrial microbiology, gene expression technology, and cell culture technology.”  (\u003ci\u003eChemical Engineering Progress\u003c\/i\u003e, 1 August 2013)\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART I INTRODUCTION 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Bioprocess Design, Computer-Aided 5\u003cbr\u003e \u003ci\u003eVictor Papavasileiou, Charles Siletti, Alexandros Koulouris, and Demetri Petrides\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART II DOWNSTREAM RECOVERY OF CELLS AND PROTEIN CAPTURE 25\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2 Cell Separation, Centrifugation 27\u003cbr\u003e \u003ci\u003eHans Axelsson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Cell Disruption, Micromechanical Properties 49\u003cbr\u003e \u003ci\u003eIngo Kampen and Arno Kwade\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Cell Separation, Yeast Flocculation 65\u003cbr\u003e \u003ci\u003eEduardo V. Soares\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Cell Wall Disruption and Lysis 81\u003cbr\u003e \u003ci\u003eF. A. P. Garcia\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Expanded Bed Chromatography, Surface Energetics of Biomass Deposition 95\u003cbr\u003e \u003ci\u003eMarcelo Fernandez Lahore, Oscar Aguilar, Rami Reddy Vennapusa and Muhammad Aasin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Filter Aids 107\u003cbr\u003e \u003ci\u003eTony Hunt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Protein Adsorption, Expanded Bed 115\u003cbr\u003e \u003ci\u003eSiddartha Ghose\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART III PROCESS DEVELOPMENT IN DOWNSTREAM PURIFICATION 127\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9 Scaledown of Biopharmaceutical Purification Operations 129\u003cbr\u003e \u003ci\u003eAnurag S. Rathore and Varsha S. Joshi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Adsorption in Simulated Moving Beds (SMB) 147\u003cbr\u003e \u003ci\u003eCesar C. Santana, Ivanildo J. Silva Jr., Diana C. S. Azevedo, and Amaro G. Barreto Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Adsorption of Proteins with Synthetic Materials 179\u003cbr\u003e \u003ci\u003eJoseph McGuire and Omkar Joshi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Affinity Fusions for Protein Purification 191\u003cbr\u003e \u003ci\u003eSusanne Gräslund and Martin Hammarström\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Bioseparation, Magnetic Particle Adsorbents 201\u003cbr\u003e \u003ci\u003eUrs Alexander Peuker, Owen Thomas, Timothy John Hobley, Mathias Franzreb, Sonja Berensmeier, Maria Shäfer, and Birgit Hickstein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 High Throughput Technologies in Bioprocess Development 221\u003cbr\u003e \u003ci\u003eTrent Carrier, Eva Heldin, Mattias Ahnfelt, Eggert Brekkan, Richard Hassett, Steve Peppers, Gustav Rodrigo, Greg Van Slyke, and David (Xiqaojian) Zhao\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Large-Scale Protein Purification, Self-Cleaving Aggregation Tags 257\u003cbr\u003e \u003ci\u003eIraj Ghazi and David W. Wood\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Lipopolysaccharide, LPS removal, Depyrogenation 269\u003cbr\u003e \u003ci\u003ePérola O. Magalhães and Adalberto Pessoa Jr.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Porous Media in Biotechnology 277\u003cbr\u003e \u003ci\u003eManuel Mota, Alexander Yelshin, and Inna Yelshina\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 Protein Aggregation and Precipitation, Measurement and Control 293\u003cbr\u003e \u003ci\u003eCatherine H. Schein\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART IV EQUIPMENT DESIGN FOR DOWNSTREAM RECOVERY AND PROTEIN PURIFICATION 325\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19 Cleaning and Sanitation in Downstream Processes 327\u003cbr\u003e \u003ci\u003eGail Sofer, Craig Robinson, Joanthan Yourkin, Tina Pitarresi, and Darcy Birse\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Clean-in-place 343\u003cbr\u003e \u003ci\u003ePhil J. Bremer and Richard Brent Seale\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 Large Scale Chromatography Columns, Modeling Flow Distribution 353\u003cbr\u003e \u003ci\u003eZhiwu Fang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 Pumps, Industrial 373\u003cbr\u003e \u003ci\u003eBob Stover and Ed Domanico\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART V DOWNSTREAM cGMP OPERATIONS 389\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e23 Affinity Chromatography of Plasma Proteins 391\u003cbr\u003e \u003ci\u003eMirjana Radosevich and Thierry Burnouf\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 Antibody Purification, Monoclonal and Polyclonal 405\u003cbr\u003e \u003ci\u003eJames J. Reilly and Michiel E. Ultee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 Chromatographic Purification of Virus Particles 415\u003cbr\u003e \u003ci\u003ePete Gagnon\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 Chromatography, Hydrophobic Interactions 437\u003cbr\u003e \u003ci\u003ePer Karsnäs\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Chromatography, Radar Flow 449\u003cbr\u003e \u003ci\u003eTingyue Gu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Drying, Biological Materials 465\u003cbr\u003e \u003ci\u003eChung Lim Law and Arun S. Mujumdar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Freeze-Drying, Pharmaceuticals 485\u003cbr\u003e \u003ci\u003eJinsong Liu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Freezing, Biopharmaceutical 505\u003cbr\u003e \u003ci\u003ePhilippe Lam and Jamie Moore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Membrane Chromatography 521\u003cbr\u003e \u003ci\u003eJohn Pieracci and Jörg Thömmes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 Membrane Separations 545\u003cbr\u003e \u003ci\u003eManohar Kalyanpur\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 Plasmid Purification 557\u003cbr\u003e \u003ci\u003eH .S. C. Barbosa and J. C. Marcos\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Protein Chromatography, Manufacturing Scale 571\u003cbr\u003e \u003ci\u003eJoseph Bertolini\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Protein Crystallization, Kinetics 579\u003cbr\u003e \u003ci\u003eGianluca Di Profio, Efrem Curcio, and Enrico Drioli\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e36 Protein Purification, Aqueous Liquid Extraction 603\u003cbr\u003e \u003ci\u003eMaria-Regina Kula and Klaus Selber\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e37 Protein Ultrafiltration 617\u003cbr\u003e \u003ci\u003eRobert van Reis and Andrew L. Zydney\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e38 Virus Retentive Filters 641\u003cbr\u003e \u003ci\u003eGeorge Miesegaes, Scott Lute, Hazel Aranha, and Kurt Brorson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART VI BIOPHARMACEUTICAL FACILITY VALIDATION 655\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e39 Biopharmaceutical Facility Design and Validation 657\u003cbr\u003e \u003ci\u003eJeffrey N. Odum\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e40 Closed Systems in Bioprocessing 677\u003cbr\u003e \u003ci\u003eJeffrey Odum\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e41 Facility Design for Single Use (SU) Downstream Materials 685\u003cbr\u003e \u003ci\u003eRobert Z. Maigetter, Tom Piombino, Christian Wood, Tom Gervais, Claudio Thomasin, Bryan Shingle, Dave A. Wareheim, and David Clark\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e42 eGMPs for Production Rooms 715\u003cbr\u003e \u003ci\u003eClaude Arlois, Jean Didelez, Patrick Florent, and Guy Godeau\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e43 Heating, Ventilation, and Air Conditioning 731\u003cbr\u003e \u003ci\u003eDennis Dobie\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e44 Sterilization-in-Place (SIP) 747\u003cbr\u003e \u003ci\u003eP. T. Noble\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART VII FDA cGMP REGULATORY COMPLIANCE 757\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e45 Pharmaceutical Bioburden Testing 759\u003cbr\u003e \u003ci\u003eNathaniel G. Hentz, PhD\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e46 Chromatography, Industrial Scale Validation 775\u003cbr\u003e \u003ci\u003eSandy Weinberg and Carl A. Rockburne\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e47 GMPs and GLSPs 795\u003cbr\u003e \u003ci\u003eBeth H. Junker\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e48 Quality by Design (QBD) 815\u003cbr\u003e \u003ci\u003eRakhi B. Shah, Jun T. Park, Erik K. Read, Mansoor A. Khan, and Kurt Brorson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e49 Regulatory Requirements, European Community 829\u003cbr\u003e \u003ci\u003eGary Walsh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 843\u003c\/p\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Default Title","offer_id":53186828566871,"sku":"9781118131244","price":204.26,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/bookcurl.com\/products\/downstream-industrial-biotechnology-9781118131244","provider":"Book Curl","version":"1.0","type":"link"}