{"product_id":"dna-repair-and-replication-9780815345992","title":"DNA Repair and Replication","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cem\u003eDNA Repair and Replication\u003c\/em\u003e brings together contributions from active researchers. The first part of this book covers most aspects of the DNA damage response, emphasizing the relationship to replication stress. The second part concentrates on the relevance of this to human disease, with particular focus on both the causes and treatments which make use of DNA Damage Repair (DDR) pathways.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eKey Selling Features:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eChapters written by leading researchers\u003c\/li\u003e\n\u003cli\u003eIncludes description of replication processes, causes of damage, and methods of repair\u003c\/li\u003e\n\u003c\/ul\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface \u003c\/p\u003e\u003cp\u003eEditors \u003c\/p\u003e\u003cp\u003eContributors \u003c\/p\u003e\u003cp\u003e1. Introduction \u003c\/p\u003e\u003cp\u003eJohn J. Reynolds, Roger J. A. Grand, and Martin R. Higgs\u003c\/p\u003e\u003cp\u003e2. DNA Replication and Cell Cycle Control \u003c\/p\u003e\u003cp\u003eSara Priego Moreno, Rebecca M. Jones, and Agnieszka Gambus\u003c\/p\u003e\u003cp\u003e3. DNA Replication Termination and Genomic Instability \u003c\/p\u003e\u003cp\u003eRebecca M. Jones, Sara Priego Moreno, and Agnieszka Gambus\u003c\/p\u003e\u003cp\u003e4. Mechanisms of DNA Damage Tolerance \u003c\/p\u003e\u003cp\u003eCyrus Vaziri and Anastasia Zlatanou\u003c\/p\u003e\u003cp\u003e5. The Repair of DNA Single-Strand Breaks and DNA Adducts: Mechanisms and Links to Human Disease \u003c\/p\u003e\u003cp\u003eAlicja Winczura and John J. Reynolds\u003c\/p\u003e\u003cp\u003e6. Homologous Recombination at Replication Forks \u003c\/p\u003e\u003cp\u003eEva Petermann\u003c\/p\u003e\u003cp\u003e7. Mechanism of Double-Strand Break Repair by Non-Homologous End Joining \u003c\/p\u003e\u003cp\u003eMichal Malewicz\u003c\/p\u003e\u003cp\u003e8. Protein Methylation and the DNA Damage Response \u003c\/p\u003e\u003cp\u003eMartin R. Higgs and Clare Davies\u003c\/p\u003e\u003cp\u003e9. Ubiquitin, SUMO and the DNA Double-Strand Break Response \u003c\/p\u003e\u003cp\u003eRuth M. Densham, Alexander J. Garvin, and Joanna R. Morris\u003c\/p\u003e\u003cp\u003e10. Transcription in the Context of Genome Stability Maintenance \u003c\/p\u003e\u003cp\u003eMarco Saponaro\u003c\/p\u003e\u003cp\u003e11. RNA Binding Proteins and the DNA Damage Response \u003c\/p\u003e\u003cp\u003eRoger J. A. Grand\u003c\/p\u003e\u003cp\u003e12. DNA Replication and Inherited Human Disease \u003c\/p\u003e\u003cp\u003eJohn J. Reynolds and Grant S. Stewart\u003c\/p\u003e\u003cp\u003e13. Ataxia Telangiectasia and Ataxia Telangiectasia–Like Disorders \u003c\/p\u003e\u003cp\u003eA. Malcolm R. Taylor\u003c\/p\u003e\u003cp\u003e14. DNA Repair Mechanisms in Stem Cells and Implications during Ageing \u003c\/p\u003e\u003cp\u003eRachel Bayley and Paloma Garcia\u003c\/p\u003e\u003cp\u003e15. Targeting Replication Stress in Sporadic Tumours \u003c\/p\u003e\u003cp\u003eMarwan Kwok and Tatjana Stankovic\u003c\/p\u003e\u003cp\u003e16. A Few of the Many Outstanding Questions \u003c\/p\u003e\u003cp\u003eJohn J. Reynolds and Roger J. A. Grand\u003c\/p\u003e\u003cp\u003eIndex\u003c\/p\u003e","brand":"Taylor \u0026 Francis Inc","offers":[{"title":"Default Title","offer_id":49405924901207,"sku":"9780815345992","price":75.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780815345992.jpg?v=1730493925","url":"https:\/\/bookcurl.com\/products\/dna-repair-and-replication-9780815345992","provider":"Book Curl","version":"1.0","type":"link"}