{"product_id":"contemporary-topics-in-immunobiology-immunobiology-of-oncogenic-viruses-6-9781468430530","title":"Contemporary Topics in Immunobiology Immunobiology Of Oncogenic Viruses 6","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThese procedures have, in turn, resulted in molecular probes that allow more definitive evaluation of the host response to its virus and to the tumor cell with which the virus or its precursors are associated.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e1 Comparative Immunology of Carcinogenesis by DNA Viruses.- I. Introduction.- II. Properties of Oncogenic DNA Viruses.- III. Oncogenic Potential of DNA Viruses in Vivo.- A. Papovaviruses.- B. Adenoviruses.- C. Herpesviruses.- IV. Oncogenic Potential of Defective Genomes.- A. Oncogenicity of Defective Viruses Produced by Exogenous Treatment.- B. Oncogenic Potential of Naturally Occurring Defective Genomes.- V. Neoplastic Transformation in Vitro by DNA Viruses.- A. Papovaviruses.- B. Adenoviruses.- C. Herpesviruses.- VI. Role of Virus Genome in Cell Transformation.- VII. Antigens Associated with DNA-Virus-Transformed Cells.- A. Intracellular Antigens.- B. Antigens Associated with the Surface of DNA-Virus-Transformed Cells.- VIII. Genetic Origin of DNA-Virus-Specified Antigens.- A. Origin of Intracellular Antigens.- B. Origin of Cell-Surface Antigens.- IX. Immune Response of the Host to DNA-Tumor-Virus-Induced Antigens.- A. Papovaviruses (SV40 and Polyoma).- B. Other Papovaviruses and Adenoviruses.- C. Herpesviruses.- X. Role of DNA-Virus-Induced Antigens in Neoplasia.- XI. Conclusions.- XII. References.- 2 Immunity to Leukemia, Lymphoma, and Fibrosarcoma in Cats: A Case for Immunosurveillance.- I. Introduction.- II. Immunosurveillance Hypothesis.- III. Feline Oncornaviruses.- IV. Feline Oncornavirus-Associated Cell Membrane Antigen.- V. Laboratory-Induced and Naturally Occurring Tumors of Cats.- A. Horizontal Transmission.- B. Immunosuppressive Potential of FeLV.- VI. Immune Response to Laboratory-Induced Tumors.- VII. Immune Response to Naturally Occurring Leukemia and Lymphoma.- VIII. Summary and Conclusions.- IX. References.- 3 Intracellular and Systemic Regulation of Biologically Distinguishable Endogenous Type C RNA Viruses of Mouse Cells.- I. Introduction.- II. Evidence for Three Classes of Biologically Distinguishable Endogenous Mouse Type C Viruses.- III. Differential Activation of Endogenous Viruses.- IV. A Gene Affecting Expression of Class I Virus.- V. A Gene Influencing the Magnitude of Release of Class III Endogenous Virus.- VI. Susceptibility to Exogenous Infection of Mouse Cells by Xenotropic Virus.- VII. High-Titered Neutralizing Activity Directed Against Xenotropic Virus in Normal Mouse Sera.- VIII. Activation of Type C Viruses from Lymphoid Cells Following Antigenic Stimulation.- IX. Biological Functions of Endogenous Type C Viruses.- X. References.- 4 Mammalian C-Type Oncornaviruses: Relationships between Viral Structural and Cell-Surface Antigens and Their Possible Significance in Immunological Defense Mechanisms.- I. Introduction.- II. Morphology of Mammalian C-Type Viruses.- III. Isolation and Physicochemical Characterization of Structural Polypeptides of Murine and Feline Viruses.- IV. Antigenic and Other Biological Properties of the Structural Polypeptides.- A. FLV.- B. FeLV.- V. Localization of the Virion Proteins and Glycoproteins in the Particle Structure.- VI. Viral Structural Antigens on the Cell Surface.- VII. Autogenous Immunity in Mice to Viral Structural Antigens.- VIII. Immunogenic Potency of Isolated Viral Proteins and Glycoproteins.- IX. Seroimmunotherapy of C-Type Virus Infections.- X. Concluding Remarks.- XI. References.- 5 Natural Immunity to Endogenous Oncornaviruses in Mice.- I. Introduction.- II. Widespread Occurrence of Natural Antibodies to MuLV.- III. Characterization of the Immune Response.- IV. Virus Specificity.- V. Autogenous Humoral Response to Virus-Induced Cell-Surface Antigens.- VI. Discussion.- VII. References.- 6 Biological and Structural Pleomorphism of the Oncornavirus Envelope Glycoprotein, gp70.- I. Introduction.- II. MuLV gp70 Is a Surface Component of Virus Particles.- III. MuLV gp70 Is a Surface Component of Infected Cells.- IV. MuLV gp70 Is a Component of the Surface of MuLV-Induced Lymphomas.- V. MuLV gp70 May Be Expressed in Normal Cells.- VI. Host Functions and Viral Genes.- VII. References.- 7 Autoimmunity, Oncornaviruses, and Lymphomagenesis.- I. Introduction.- II. Immunological Activation of C-Type Viruses.- A. Skin Graft Rejection Reactions.- B. Graft-Versus-Host Reactions.- III. Virus-Induced Autoimmunity and Lymphomagenesis.- IV. Discussion.- V. Summary.- VI. References.- 8 Natural Immunity to Murine Mammary Tumor Viruses.- I. Historical Review.- II. Immunofluorescence Studies on the Presence of Antibodies to MTV in Mouse Sera.- III. References.- 9 Immunogenicity and MuMTV-like Antigenicity of Human Breast Cancer Tissues.- I. Introduction.- II. Immunogenicity of Human Breast Cancer.- III. Immunological Measurements.- A. Autologous Breast Cancer Tissue.- B. Cross-Reactivity against MuMTV and Immunogenic Breast Cancer.- IV. Physicochemical Measurements.- A. SDS PAGE.- B. Native Proteins PAGE.- C. Molecular Hybridization.- V. Comments.- VI. References.- 10 Clinical Implications of Immunity to Oncogenic Viruses.- I. Introduction.- II. Etiology.- III. Prevention.- IV. Immunodiagnosis.- V. Therapy.- VI. Summary and Conclusions.- VII. References.","brand":"Springer Us","offers":[{"title":"Default Title","offer_id":51742566678871,"sku":"9781468430530","price":42.74,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781468430530.jpg?v=1758385268","url":"https:\/\/bookcurl.com\/products\/contemporary-topics-in-immunobiology-immunobiology-of-oncogenic-viruses-6-9781468430530","provider":"Book Curl","version":"1.0","type":"link"}