{"product_id":"computational-protein-design-1529-methods-in-molecular-biology-9781493966356","title":"Computational Protein Design 1529 Methods in","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThe aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.     Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePart I: Computational Protein Design1.\tThe Framework of Computational Protein DesignIlan Samish\u003cbr\u003e2.\tAchievements and Challenges in Computational Protein DesignIlan Samish\u003cbr\u003e3.\tProduction of Computationally Designed Small Soluble- and Membrane-Proteins: Cloning, Expression and PurificationBarsha Tripathy and Rudresh Acharya\u003cbr\u003e4.\tDeterministic Search methods for Computational Protein DesignSeydou Traoré, David Allouche, Isabelle André Thomas Schiex, and Sophie Barbe\u003cbr\u003e5.\tGeometric Potentials for Computational Protein Sequence DesignJie Li and Patrice Koehl \u003cbr\u003e6.\tModeling Binding Affinity of Pathological Mutations for Computational Protein DesignMiguel Romero-Durana, Chiara Pallara, Fabian Glaser, and Juan Fernández-Recio\u003cbr\u003e7.\tMultistate Computational Protein Design with Backbone EnsemblesJames A. Davey and Roberto A. Chica\u003cbr\u003e8.\tIntegration of Molecular Dynamics Based Predictions into the Optimization of de novo Protein Designs: Limitations and BenefitsHenrique F. Carvalho, Arménio J. M. Barbosa, Ana C. A. Roque, Olga Iranzo, and Ricardo J. F. Branco\u003cbr\u003e9.\tApplications of Normal Mode Analysis Methods in Computational Protein DesignVincent Frappier, Matthieu Chartier, and Rafael NajmanovichPart II: Software of Computational Protein Design Applications10.\tComputational Protein Design Under a Given backbone Structure with a Statistical Energy FunctionPeng Xiong, Quan Chen, and Haiyan Liu\u003cbr\u003e11.\tComputational Protein Design Through Grafting and StabilizationCheng Zhu, David D. Mowrey, and Nikolay V. Dokholyan\u003cbr\u003e12.\tAn Evolution Based Approach to de novo Protein DesignJeffrey R. Brender, David Shultis, Naureen Aslam, and Yang Zhang\u003cbr\u003e13.\tParallel Computational Protein Design Yichao Zhou, Bruce R. Donald, and Jianyang Zeng\u003cbr\u003e14.\tBindML\/BindML+: Detecting Protein-Protein Interaction Interface Propensity from Amino Acid Substitution PatternsQing Wei, David La, and Daisuke Kihara\u003cbr\u003e15.\tOSPREY Predicts Resistance Mutations using Positive and Negative Computational Protein DesignAdegoke Ojewole, Anna Lowegard, Pablo Gainza, Stephanie M. Reeve, Ivelin Georgiev, Amy C. Anderson, and Bruce R. DonaldPart III: Computational Protein Design of Specific Targets16.\tEvolution-inspired Computational Design of Symmetric ProteinsArnout R.D. Voet, David Simoncini, Jeremy R.H. Tame, and Kam Y. J. Zhang\u003cbr\u003e17.\tA Protocol for the Design of Protein and Peptide Nanostructure Self-assemblies Exploiting Synthetic Amino Acids\u003cnurit haspel jie zheng carlos aleman david zanuy and ruth nussinov\u003e\u003c\/nurit\u003e18.\tProbing Oligomerized Conformations of Defensin in the MembraneWenxun Gan, Dina Schneidman, Ning Zhang, Buyong Ma, and Ruth Nussinov\u003cbr\u003e19.\tComputational Design of Ligand Binding ProteinsChristine E. Tinberg and Sagar D. Khare\u003cbr\u003e20.\tEpiSweep: Computationally-driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity while Maintaining FunctionYoonjoo Choi, Deeptak Verma, Karl E. Griswold, and Chris Bailey-Kellogg\u003cbr\u003e21.\tComputational Tools for Aiding Rational Antibody DesignKonrad Krawczyk, James Dunbar, and Charlotte M Deane\u003cbr\u003e22.\tComputational Design of Membrane Curvature-Sensing PeptidesArmando Jerome de Jesus and Hang Yin\u003cbr\u003e23.\tComputational Tools for Allosteric Drug Discovery: Site Identification and Focus Library DesignWenkang Huang, Ruth Nussinov, and Jian Zhang\u003cbr\u003e","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":51040590201175,"sku":"9781493966356","price":134.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781493966356.jpg?v=1750947209","url":"https:\/\/bookcurl.com\/products\/computational-protein-design-1529-methods-in-molecular-biology-9781493966356","provider":"Book Curl","version":"1.0","type":"link"}