{"product_id":"comprehensive-chromatography-in-combination-with-mass-spectrometry-wiley-series-on-mass-spectrometry-9780470434079","title":"Comprehensive Chromatography in Combination with","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e* Comprehensive chromatography represents one of the most powerful tools in the separation of complex mixtures    * The book is both broad covering many areas of techniques and applications while still being focused to a specific topic.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e“It offers comprehensive coverage of the topic of comprehensive multidimensional separations, at a level that makes it a useful reference for scientists working in the field, or as a primary textbook for a graduate-level course on advanced separation techniques.”  (\u003ci\u003eAnal Bioanal Chem\u003c\/i\u003e, 2012)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eContributors ix\u003c\/b\u003e  \u003cp\u003e\u003cb\u003ePreface xi\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction 1\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eLuigi Mondello, Peter Q. Tranchida, and Keith D. Bartle\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Two-Dimensional Chromatography–Mass Spectrometry: A 50-Year-Old Combination, 2\u003c\/p\u003e \u003cp\u003e1.2 Shortcomings of One-Dimensional Chromatography, 3\u003c\/p\u003e \u003cp\u003e1.3 Benefits of Two-Dimensional Chromatography, 6\u003c\/p\u003e \u003cp\u003e1.4 Book Content, 7\u003c\/p\u003e \u003cp\u003e1.5 Final Considerations, 11\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Multidimensional Gas Chromatography: Theoretical Considerations 13\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eLeonid M. Blumberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Symbols, 15\u003c\/p\u003e \u003cp\u003e2.2 One-Dimensional GC, 17\u003c\/p\u003e \u003cp\u003e2.3 Comprehensive GC × GC, 31\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Multidimensional Liquid Chromatography: Theoretical Considerations 65\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePavel Jandera\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Two-Dimensional LC Techniques, 66\u003c\/p\u003e \u003cp\u003e3.2 Peak Capacity in HPLC: One- and Multidimensional Separations, 69\u003c\/p\u003e \u003cp\u003e3.3 Orthogonality in Two-Dimensional LC–LC Systems, 73\u003c\/p\u003e \u003cp\u003e3.4 Sample Dimensionality and Structural Correlations, 75\u003c\/p\u003e \u003cp\u003e3.5 Separation Selectivity and Selection of Phase Systems in Two-Dimensional LC–LC, 79\u003c\/p\u003e \u003cp\u003e3.6 Programmed Elution in Two-Dimensional HPLC, 81\u003c\/p\u003e \u003cp\u003e3.7 Fraction Transfer Modulation in Comprehensive LC × LC: Additional Band Broadening, 87\u003c\/p\u003e \u003cp\u003e3.8 Future Perspectives, 89\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Gas Chromatography 93\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAhmed Mostafa, Tadeusz G´orecki, Peter Q. Tranchida, and Luigi Mondello\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Fundamentals of GC × GC, 94\u003c\/p\u003e \u003cp\u003e4.2 Modulation, 96\u003c\/p\u003e \u003cp\u003e4.3 GC × GC Data Interpretation, 97\u003c\/p\u003e \u003cp\u003e4.4 GC × GC Instrumentation, 100\u003c\/p\u003e \u003cp\u003e4.5 Thermal Modulators, 101\u003c\/p\u003e \u003cp\u003e4.6 Comprehensive Two-Dimensional GC Method Optimization, 115\u003c\/p\u003e \u003cp\u003e4.7 Final Remarks, 140\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Flow-Modulated Comprehensive Two-Dimensional Gas Chromatography 145\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eJohn V. Seeley\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Timing Requirements of GC × GC Modulators, 145\u003c\/p\u003e \u003cp\u003e5.2 Criteria for Evaluating Modulators, 150\u003c\/p\u003e \u003cp\u003e5.3 Forms of Modulation, 151\u003c\/p\u003e \u003cp\u003e5.4 Single-Stage Flow Modulation, 152\u003c\/p\u003e \u003cp\u003e5.5 Two-Stage Flow Modulation, 157\u003c\/p\u003e \u003cp\u003e5.6 Summary of Flow Modulators, 167\u003c\/p\u003e \u003cp\u003e5.7 Brief Comparison to Thermal Modulation, 169\u003c\/p\u003e \u003cp\u003e5.8 Concluding Remarks, 169\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Comprehensive Two-Dimensional Gas Chromatography Combined with Mass Spectrometry 171\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePeter Q. Tranchida, Luigi Mondello, Samuel D. H. Poynter, and Robert A. Shellie\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Instrument Requirements for GC × GC–MS, 173\u003c\/p\u003e \u003cp\u003e6.2 Data Processing of GC × GC–TOF MS Results, 180\u003c\/p\u003e \u003cp\u003e6.3 Method Translation in GC × GC–MS, 181\u003c\/p\u003e \u003cp\u003e6.4 GC × MS, 181\u003c\/p\u003e \u003cp\u003e6.5 Conventional and Alternative Modulation Techniques for GC × GC–MS, 184\u003c\/p\u003e \u003cp\u003e6.6 GC × GC–MS Applications, 187\u003c\/p\u003e \u003cp\u003e6.7 Concluding Remarks, 232\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Detector Technologies and Applications in Comprehensive Two-Dimensional Gas Chromatography 243\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePhilip J. Marriott\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Detection in GC × GC, 244\u003c\/p\u003e \u003cp\u003e7.2 Comments on GC × GC with Mass Spectrometry, 249\u003c\/p\u003e \u003cp\u003e7.3 Flame Ionization Detection in GC × GC, 250\u003c\/p\u003e \u003cp\u003e7.4 Electron Capture Detection in GC × GC, 254\u003c\/p\u003e \u003cp\u003e7.5 Sulfur Chemiluminescence Detection in GC × GC, 260\u003c\/p\u003e \u003cp\u003e7.6 Nitrogen Chemiluminescence Detection in GC × GC, 263\u003c\/p\u003e \u003cp\u003e7.7 Atomic Emission Detection in GC × GC, 265\u003c\/p\u003e \u003cp\u003e7.8 Thermionic Detection in GC × GC, 267\u003c\/p\u003e \u003cp\u003e7.9 Flame Photometric Detection in GC × GC, 269\u003c\/p\u003e \u003cp\u003e7.10 Case Study of GC × GC with Selective Detection, 272\u003c\/p\u003e \u003cp\u003e7.11 Dual Detection with GC × GC, 274\u003c\/p\u003e \u003cp\u003e7.12 Conclusions, 275\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 History, Evolution, and Optimization Aspects of Comprehensive Two-Dimensional Liquid Chromatography 281\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eIsabelle Fran¸cois, Koen Sandra, and Pat Sandra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Method Development and Instrumentation, 282\u003c\/p\u003e \u003cp\u003e8.2 Technical Problems in Comprehensive Liquid Chromatography, 309\u003c\/p\u003e \u003cp\u003e8.3 Detection, 314\u003c\/p\u003e \u003cp\u003e8.4 Data Representation, 315\u003c\/p\u003e \u003cp\u003e8.5 Instrumentation, 316\u003c\/p\u003e \u003cp\u003e8.6 Milestones in Comprehensive Liquid Chromatography, 317\u003c\/p\u003e \u003cp\u003e8.7 Applications, 320\u003c\/p\u003e \u003cp\u003e8.8 Beyond Two-Dimensional Chromatography, 320\u003c\/p\u003e \u003cp\u003e8.9 Comparison of LC × LC and Off-Line 2D LC, 321\u003c\/p\u003e \u003cp\u003e8.10 Conclusions, 325\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Comprehensive Two-Dimensional Liquid Chromatography Combined with Mass Spectrometry 331\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePaola Dugo, Luigi Mondello, Francesco Cacciola, and Paola Donato\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 HPLC–MS, 332\u003c\/p\u003e \u003cp\u003e9.2 LC × LC–MS Instrumentation and Method Development, 334\u003c\/p\u003e \u003cp\u003e9.3 LC × LC–MS Applications, 336\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Comprehensive Two-Dimensional Liquid Chromatography Applications 391\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePaola Dugo, Luigi Mondello, Francesco Cacciola, and Paola Donato\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Comprehensive 2D LC Separation of Synthetic and Natural Polymers, 392\u003c\/p\u003e \u003cp\u003e10.2 Comprehensive 2D LC Separation of Natural Products and Antioxidants, 399\u003c\/p\u003e \u003cp\u003e10.3 Comprehensive 2D LC Separation of Pharmaceutical and Environmental Compounds, 412\u003c\/p\u003e \u003cp\u003e10.4 Comprehensive 2D LC Separation of Proteins and Peptides, 417\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Other Comprehensive Chromatography Methods 429\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eIsabelle Fran¸cois, Pat Sandra, Danilo Sciarrone, and Luigi Mondello\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Online Two-Dimensional Liquid Chromatography–Gas Chromatography, 430\u003c\/p\u003e \u003cp\u003e11.2 Online Two-Dimensional Supercritical Fluid Chromatography–Gas Chromatography, 440\u003c\/p\u003e \u003cp\u003e11.3 Online Two-Dimensional Supercritical Fluid Chromatography–Supercritical Fluid Chromatography, 440\u003c\/p\u003e \u003cp\u003e11.4 Online Two-Dimensional Supercritical Fluid Chromatography-Liquid Chromatography, 442\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Comprehensive Chromatography Data Interpretation Technologies 449\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eElizabeth M. Humston and Robert E. Synovec\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Higher-Order Data Structure, 450\u003c\/p\u003e \u003cp\u003e12.2 Modifications of First-Order Data-Handling Approaches, 453\u003c\/p\u003e \u003cp\u003e12.3 Visualization, 456\u003c\/p\u003e \u003cp\u003e12.4 Mass Spectral Detection, 461\u003c\/p\u003e \u003cp\u003e12.5 Chemometrics, 463\u003c\/p\u003e \u003cp\u003e12.6 Summary of Data Interpretation Technologies, 472\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIndex 477\u003c\/b\u003e\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49402331988311,"sku":"9780470434079","price":107.06,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780470434079.jpg?v=1730480091","url":"https:\/\/bookcurl.com\/products\/comprehensive-chromatography-in-combination-with-mass-spectrometry-wiley-series-on-mass-spectrometry-9780470434079","provider":"Book Curl","version":"1.0","type":"link"}