{"product_id":"clinical-epidemiology-9781493924271","title":"Clinical Epidemiology","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eFocusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the ethics associated with doing a research project in humans, and the definition of various biases that occur in clinical research. From there, it continues by examining issues of design, measurement, and analysis associated with various research designs, including determination of risk in longitudinal studies, assessment of therapy in randomized controlled clinical trials, and evaluation of diagnostic tests, and then delves into the more specialized area of clinical genetic research, before concluding with basic methods used in evidence-based decision making including critical appraisal, aggregation of multiple studies using meta-analysis, health technology as\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePart I: Introduction\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e1. On Framing the Research Question and Choosing the Appropriate Research Design\u003c\/p\u003e\u003cp\u003e            Patrick S. Parfrey and Pietro Ravani\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e2. Research Ethics for Clinical Researchers\u003c\/p\u003e\u003cp\u003e            John D. Harnett and Richard Neuman\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e3. Definitions of Bias in Clinical Research\u003c\/p\u003e\u003cp\u003e            Geoffrey Warden\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart II: Longitudinal Studies\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e4. Longitudinal Studies 1: Determination of Risk\u003c\/p\u003e\u003cp\u003e            Sean W. Murphy\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e5. Longitudinal Studies 2: Modeling Data Using Multivariate Analysis\u003c\/p\u003e\u003cp\u003e            Pietro Ravani, Brendan J. Barrett, and Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e6. Longitudinal Studies 3: Data Modeling Using Standard Regression Models and Extensions\u003c\/p\u003e\u003cp\u003e            Pietro Ravani, Brendan J. Barrett, and Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e7. Longitudinal Studies 4: Matching Strategies to Evaluate Risk\u003c\/p\u003e\u003cp\u003e            Matthew T. James\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e8. Longitudinal Studies 5: Development of Risk Prediction Models for Patients with Chronic Disease\u003c\/p\u003e\u003cp\u003e            Navdeep Tangri and Claudio Rigatto\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart III: Randomized Controlled Clinical Trials\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e9. Randomized Controlled Trials 1: Design\u003c\/p\u003e\u003cp\u003e            Bryan M. Curtis, Brendan J. Barrett, and Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e10. Randomized Controlled Trials 2: Analysis\u003c\/p\u003e\u003cp\u003e            Robert N. Foley\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e11. Randomized Controlled Trials 3: Measurement and Analysis of Patient-Reported Outcomes\u003c\/p\u003e\u003cp\u003e            Michelle M. Richardson, Megan E. Grobert, and Klemens B. Meyer\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e12. Randomized Controlled Trials 4: Biomarkers and Surrogate Outcomes\u003c\/p\u003e\u003cp\u003e            Claudio Rigatto and Brendan J. Barrett\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e13. Randomized Controlled Trials 5: Determining the Sample Size and Power for Clinical Trials and Cohort Studies\u003c\/p\u003e\u003cp\u003e            Tom Greene\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e14. Randomized Controlled Trials 6: On Contamination and Estimating the Actual Treatment Effect\u003c\/p\u003e\u003cp\u003e            Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e15. Randomized Controlled Trials 7: Analysis and Interpretation of Quality of Life Scores\u003c\/p\u003e\u003cp\u003e            Robert N. Foley and Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e16. Randomized Controlled Trials 8: Planning, Monitoring, and Execution\u003c\/p\u003e\u003cp\u003e            Elizabeth Hatfield, Elizabeth Dicks, and Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart IV: The Basics for Other Clinical Epidemiology Methods\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e17. Evaluation of Diagnostic Tests\u003c\/p\u003e\u003cp\u003e            John M. Fardy and Brendan J. Barrett\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e18. Qualitative Research in Clinical Epidemiology\u003c\/p\u003e\u003cp\u003e            Deborah M. Gregory and Christine Y. Way\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e19. Health Economics in Clinical Research\u003c\/p\u003e\u003cp\u003e            Braden J. Manns\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart V: Clinical Genetic Research\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e20. Clinical Genetic Research 1: Bias\u003c\/p\u003e\u003cp\u003e            Susan Stuckless and Patrick S. Parfrey\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e21. Clinical Genetic Research 2:  Genetic Epidemiology of Complex Phenotypes\u003c\/p\u003e\u003cp\u003e            Darren D. O’Rielly and Proton Rahman\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e22. Clinical Genetic Research 3: Genetics ELSI (Ethical, Legal and Social Issues) Research\u003c\/p\u003e\u003cp\u003e            Daryl Pullman and Holly Etchegary\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003ePart VI: Methods in Evidence–Based Decision Making\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e23. Evidence-Based Decision Making 1: Critical Appraisal\u003c\/p\u003e\u003cp\u003e            Laurie K. Twells\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e24. Evidence-Based Decision Making 2: Systematic Reviews and Meta-Analysis\u003c\/p\u003e\u003cp\u003e            Aminu Bello, Natasha Wiebe, Amit Garg, and Marcello Tonelli\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e25. Evidence-Based Decision Making 3: Health Technology Assessment\u003c\/p\u003e\u003cp\u003e            Daria O’Reilly, Kaitryn Campbell, Meredith Vanstone, James M. Bowen, Lisa Schwartz, Nazila Assasi, and Ron Goeree\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e26. Evidence-Based Decision Making 4: Development and Limitations of Clinical Practice Guidelines\u003c\/p\u003e\u003cp\u003e            Bruce Culleton\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e27. Evidence-Based Decision-Making 5: Translational Research\u003c\/p\u003e\u003cp\u003e            Deborah M. Gregory and Laurie K. Twells\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e28. Evidence-Based Decision Making 6: Utilization of Administrative Databases for Health Services Research\u003c\/p\u003e\u003cp\u003e            Turin Chowdury and Brenda Hemmelgarn\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e29. Evidence-Based Decision Making 7: Knowledge Translation\u003c\/p\u003e\u003cp\u003e            Braden J. Manns\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e30. Evidence-Based Decision Making 8: Health Policy, A Primer for Researchers\u003c\/p\u003e\u003cp\u003e            Victor Maddalena\u003c\/p\u003e","brand":"Humana Press Inc.","offers":[{"title":"Default Title","offer_id":51019947475287,"sku":"9781493924271","price":149.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781493924271.jpg?v=1750781842","url":"https:\/\/bookcurl.com\/products\/clinical-epidemiology-9781493924271","provider":"Book Curl","version":"1.0","type":"link"}