{"product_id":"classics-in-total-synthesis-iii-further-targets-strategies-methods-9783527329588","title":"Classics in Total Synthesis III: Further Targets,","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eK.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry\u003c\/b\u003e\u003c\/p\u003e Retaining his excellent, proven approach, world-famous chemist and passionate teacher K.C. Nicolaou compiles here the important strategies and tools employed to construct complex molecules. For a total of 42 syntheses of 25 challenging natural products he explains all the key steps of the synthetic pathway, highlighting the major developments in blue-boxed sections for easier understanding, and contrasting these to other synthetic methods. Similar to its predecessors and completing the trilogy, this textbook analyzes the syntheses in a didactic manner, with several chapters including mini-reviews of key methodologies, and an emphasis on the history, mechanism, scope, and generality of the reactions. In contrast to the first two volumes, this new one features full-color frontispieces.\u003cbr\u003eA wonderful tool for learning and teaching and a must-have for all current and future organic and biochemists.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"Classics in Total Synthesis III will surely itself become a classic in the literature on the state of the art of contemporary organic synthetic chemistry.\" (Angewandte Chemie, 2011)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eINTRODUCTION: THE ADVANCING FIELD OF TOTAL SYNTHESIS\u003cbr\u003e Targets\u003cbr\u003e Strategies and Methods\u003cbr\u003e Classics in Total Synthesis III\u003cbr\u003e \u003cbr\u003e TETRODOTOXIN\u003cbr\u003e Introduction\u003cbr\u003e Kishi's Retrosynthetic Analysis and Strategy\u003cbr\u003e Kishi's Total Synthesis\u003cbr\u003e Du Bois' Retrosynthetic Analysis and Strategy\u003cbr\u003e Du Bois' Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e DISCODERMOLIDE\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e AZASPIRACID-1\u003cbr\u003e Introduction\u003cbr\u003e Nicolaou's Retrosynthetic Analysis and Strategy\u003cbr\u003e Nicolaou's Total Synthesis\u003cbr\u003e Evans' Retrosynthetic Analysis and Strategy\u003cbr\u003e Evans' Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e THIOSTREPTON\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e PENTACYCLOANAMMOXIC ACID METHYL ESTER\u003cbr\u003e Introduction\u003cbr\u003e First-Generation Retrosynthetic Analysis and Strategy\u003cbr\u003e First-Generation Total Synthesis\u003cbr\u003e Second-Generation Retrosynthetic Analysis and Strategy\u003cbr\u003e Second-Generation Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e LITTORALISONE, OSELTAMIVIR (TAMIFLU®), AND HIRSUTELLONE B\u003cbr\u003e Introduction\u003cbr\u003e Introduction to Littoralisone\u003cbr\u003e Total Synthesis of Littoralisone\u003cbr\u003e Introduction to Oseltamivir (Tamiflu®)\u003cbr\u003e Total Synthesis of Oseltamivir (Tamiflu®)\u003cbr\u003e Introduction to Hirsutellone B\u003cbr\u003e Total Synthesis of Hirsutellone B\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e RUBICORDIFOLIN AND RUBIONCOLIN B\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis of Rubicordifolin\u003cbr\u003e Total Synthesis of Rubicordifolin\u003cbr\u003e Retrosyntheticd Analysis of Rubioncolin B\u003cbr\u003e Total Synthesis of Rubioncolin B\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e CYANTHIWIGINS U AND F\u003cbr\u003e Introduction\u003cbr\u003e Phillips' Retrosynthetic Analysis and Strategy\u003cbr\u003e Phillips' Total Synthesis\u003cbr\u003e Stolz' Retrosynthetic Analysis and Strategy\u003cbr\u003e Stoltz' Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e STEPHACIDIN B\u003cbr\u003e Introduction\u003cbr\u003e Myers' Retrosynthetic Analysis and Strategy\u003cbr\u003e Meyers' Total Synthesis\u003cbr\u003e Baran's Retrosynthetic Analysis and Strategy\u003cbr\u003e Baran's Total Synthesis\u003cbr\u003e Williams' Retrosynthetic Analysis and Strategy\u003cbr\u003e Williams' Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e ABYSSOMICIN C AND ATROP-ABYSSOMICIN C\u003cbr\u003e Introduction\u003cbr\u003e Sorensen's Retrosynthetic Analysis and Strategy\u003cbr\u003e Sorensen's Total Synthesis of Abyssomicin C\u003cbr\u003e Nicolaou's Retrosynthetic Analysis and Strategy\u003cbr\u003e Nicolaou's Total Synthesis of Abyssomicin C and atrop-Abyssomicin C\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e TETRACYCLINE\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e BISANTHRAQUINONE NATURAL PRODUCTS\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy Toward 2,2'-epi-Cytoskyrin A, Rugulosin, and Rugulin\u003cbr\u003e Total Synthesis of 2,2'-epi-Cytoskyrin A, Rugulosin, and Rugulin\u003cbr\u003e Retrosynthetic Analysis and Strategy Toward Antibiotic BE-43472B\u003cbr\u003e Total Synthesis of Antibiotic BE-43472B\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e GARSUBELLIN A\u003cbr\u003e Introduction\u003cbr\u003e Sibasaki and Kanai's Retrosynthetic Analysis and Strategy\u003cbr\u003e Shibasaki and Kanai's Total Synthesis\u003cbr\u003e Danishefsky's Retrosynthetic Analysis and Strategy\u003cbr\u003e Danishefsky's Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e WELWITINDOLINONE A\u003cbr\u003e Introduction\u003cbr\u003e Baran's Retrosynthetic Analysis and Strategy\u003cbr\u003e Barans' Total Synthesis\u003cbr\u003e Wood's Retrosynthetic Analysis and Strategy\u003cbr\u003e Wood's Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e IEJIMALIDE B\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e KEDARCIDIN CHROMOPHORE AND MADUROPEPTIN CHROMOPHORE\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy for Kedarcidin Chromophore\u003cbr\u003e Total Synthesis of Kedarcidin Chromophore\u003cbr\u003e Retrosynthetic Analysis and Strategy for Maduropeptin Chromophore\u003cbr\u003e Total Synthesis of Maduropeptin Chromophore\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e BIYOUYANAGIN A\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e AZADIRACHTIN\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e RESVERATROL-DERIVED NATURAL PRODUCTS\u003cbr\u003e Introduction\u003cbr\u003e Snyder's Retrosynthetic Analysis and Strategy for a Collection of Resveratrol-Derived Natural Products\u003cbr\u003e Snyder's Total Synthesis of a Collection of Resveratrol-Derived Natural Products\u003cbr\u003e Nicolaou and Chen's Retrosynthetic Analysis and Strategy for Hopeahainol A and Hopeanol\u003cbr\u003e Nicolaou and Chen's Total Synthesis of Hopeahainol A and Hopeanol\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e CHLOROSULFOLIPID CYTOTOXIN\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e SPOROLIDE B\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e 11,11'-DIDEOXYVERTICILLIN A AND CHAETOCIN\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy for 11,11'-Dideoxyverticillin A\u003cbr\u003e Total Synthesis of 11,11'-Dideoxyverticillin A\u003cbr\u003e Retrosynthetic Analysis and Strategy for Chaetocin\u003cbr\u003e Total Synthesis of Chaetocin\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e VANNUSAL B\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e HAPLOPHYTINE\u003cbr\u003e Introduction\u003cbr\u003e Fukuyama and Tokuyama's Retrosynthetic Analysis and Strategy\u003cbr\u003e Fukuyama and Tokuyama's Total Synthesis\u003cbr\u003e Nicolaou and Chen's Retrosynthetic Analysis and Strategy\u003cbr\u003e Nicolaou and Chen's Total Synthesis\u003cbr\u003e Conclusion\u003cbr\u003e \u003cbr\u003e PALAU'AMINE\u003cbr\u003e Introduction\u003cbr\u003e Retrosynthetic Analysis and Strategy\u003cbr\u003e Total Synthesis\u003cbr\u003e Conclusion","brand":"Wiley-VCH 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