{"product_id":"chordoma-of-the-spine-a-comprehensive-review-9783030762001","title":"Chordoma of the Spine: A Comprehensive Review","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book provides a comprehensive review of the epidemiology, pathogenesis, diagnosis, and management of chordomas of the mobile spine and sacrum. Historically, knowledge about how to deliver such state-of-the-art care has not been widespread, resulting in inconsistent treatment, and, all too often, suboptimal outcomes for chordoma patients. This text is an important step towards broadening that knowledge, and, in turn, improving the care provided to chordoma patients. The book is divided into 4 parts comprising 16 chapters. The first part focuses on the pathophysiology and molecular drivers of chordoma. The second focuses on the epidemiology and clinical history, as well as the histological, oncologic, and radiographic work-up of chordoma. The third part focuses primarily on the technical aspects of surgery for chordoma. It is broken down by anatomic region, with the final two chapters focusing on the soft tissue and bony reconstruction following chordoma resection. The last part focuses on the exciting field of adjuvant therapies for chordoma. This includes both radiation therapies and novel chemotherapeutic options for recurrent, metastatic, and dedifferentiated chordoma.\u003cbr\u003e Written by world experts from leading chordoma centers, \u003ci\u003eChordoma of the Spine\u003c\/i\u003e serves as a valuable reference for spinal oncologists and general spine surgeons who may encounter chordoma patients in their practice. It provides the most up-to-date evidence regarding all aspects of treating patients with this disease. By focusing on this specific pathology of the spine, this resource condenses expert-level research into understandable treatment algorithms.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003eSection I\tPathophysiology and Molecular Mechanisms of Chordoma\u003cbr\u003e1\tNotochordal Morphogenesis and the Origin of Chordoma\tMatthew L. Goodwin, MD PhD, David C. Clever, MD PhD2\tMolecular and Genetic Mechanisms of Spinal ChordomaConnor Liu, BS; Ann Liu, MD; Chetan Bettegowda, MD\/PhD\u003cbr\u003eSection II\tEpidemiology, Clinical History, and Work-Up for Chordoma\u003cbr\u003e3\tHistorical Overview, Demographics, and Clinical Presentation of Spinal Chordoma\tZach Pennington BS, Andrew Schilling AB, Joseph H. Schwab MS MS, Daniel M. Sciubba MD4\tClinical Work up, Diagnostic Imaging and Biopsy\tDaniel Ryan, MD; John Gross, MD; Zach Pennington BS, Majid Khan, MD5\tHistopathologic Classification of Spinal Chordoma\tJohn M Gross MD, Edward F McCarthy MD6\tMulti-disciplinary Planning for Treatment\tNicholas A Shepard MD, Matthew W Colman MD\u003cbr\u003eSection III\tSurgical Management of Chordoma\u003cbr\u003e7\tSurgical Management of Chordoma of the Occipitocervical Junction\tZach Pennington BS, Jeff Ehresman BS, Andrew Schilling BA, Daniel M. Sciubba MD8\tSurgical Management of Chordoma of the Cervical Spine\tOliver G.S. Ayling MD, MSc, Nicolas Dea MD, MSc9\tSurgical Management of Chordoma of the Thoracic Spine\tDaniel G. Tobert MD, John H. Shin MD, Joseph H. Schwab MD10\tSurgical Management of Chordoma of the Lumbar Spine\tSutipat Pairojboriboon MD, Amanda Sacino MDPhD, Sheng-fu Larry Lo MD11\tSurgical Management of Chordoma of the Sacrum\tPeter S. Rose, MD, Matthew T. Houdek, MD, Cory G. Couch, MD12\tSoft Tissue Reconstruction Following Surgery for Sacral Chordoma\tRachel Skladman MD, Zach Pennington BS, Justin M. Sacks MD MBA FACS13\tVascular Reconstruction After EnBloc Resection.\tDaniel G. Tobert MD, Joseph H. Schwab MD\u003cbr\u003eSection IV\tRadiation and Chemotherapeutic Adjuvants for Chordoma\u003cbr\u003e14\tPhoton Therapy for Chordoma of the Spine\tChunzi Jenny Jin MD MSc, Yoshiya Josh Yamada MD FRCPC15\tHeavy Particle Therapy for Chordoma\tDavid J. Konieczkowski MD PhD, Reiko Imai MD, Thomas F. DeLaney MD16\tSystemic Therapy, Trials and Future Directions for Chordoma of the Spine\tDaniel J. Zabransky, MD, PhD, Zach Pennington BS, Christian Meyer, MD, MS, PhD\u003cbr\u003eIndex\u003cbr\u003e","brand":"Springer Nature Switzerland AG","offers":[{"title":"Default Title","offer_id":49415636484439,"sku":"9783030762001","price":113.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9783030762001.jpg?v=1730527603","url":"https:\/\/bookcurl.com\/products\/chordoma-of-the-spine-a-comprehensive-review-9783030762001","provider":"Book Curl","version":"1.0","type":"link"}