{"product_id":"chemical-synthesis-using-highly-reactive-metals-9781118929117","title":"Chemical Synthesis Using Highly Reactive Metals","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eWritten by the creator of Rieke metals, valuable for chemical reaction methods and efficiency, this groundbreaking book addresses a significant aspect of organic and inorganic chemistry. The author discusses synthetic methods, preparation procedures, chemical reactions, and applications for highly reactive metals and organometallic reagents.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface xvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Genesis of Highly Reactive Metals 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 General Methods of Preparation and Properties 5\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 General Methods for Preparation of Highly Reactive Metals 5\u003c\/p\u003e \u003cp\u003e2.2 Physical Characteristics of Highly Reactive Metal Powders 8\u003c\/p\u003e \u003cp\u003e2.3 Origin of the Metals’ High Reactivity 9\u003c\/p\u003e \u003cp\u003eReferences 10\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Zinc 13\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 General Methods for Preparation of Rieke Zinc 13\u003c\/p\u003e \u003cp\u003e3.2 Direct Oxidative Addition of Reactive Zinc to Functionalized Alkyl, Aryl, and Vinyl Halides 16\u003c\/p\u003e \u003cp\u003e3.3 Reactions of Organozinc Reagents with Acid Chlorides 20\u003c\/p\u003e \u003cp\u003e3.4 Reactions of Organozinc Reagents with α,β-Unsaturated Ketones 27\u003c\/p\u003e \u003cp\u003e3.5 Reactions of Organozinc Reagents with Allylic and Alkynyl Halides 30\u003c\/p\u003e \u003cp\u003e3.6 Negishi Cross-Coupling of Vinyl and Aryl Organozinc Halides 34\u003c\/p\u003e \u003cp\u003e3.7 Intramolecular Cyclizations and Conjugate Additions Mediated by Rieke Zinc 42\u003c\/p\u003e \u003cp\u003e3.8 The Formation and Chemistry of Secondary and Tertiary Alkylzinc Halides 44\u003c\/p\u003e \u003cp\u003e3.9 Electrophilic Amination of Organozinc Halides 50\u003c\/p\u003e \u003cp\u003e3.10 Reformatsky and Reformatsky-Like Reagents and Their Chemistry 52\u003c\/p\u003e \u003cp\u003e3.11 Configurationally Stable Organozinc Reagents and Intramolecular Insertion Reactions 54\u003c\/p\u003e \u003cp\u003e3.12 Preparation of Tertiary Amides via Aryl, Heteroaryl, and Benzyl Organozinc Reagents 55\u003c\/p\u003e \u003cp\u003e3.13 Preparation of 5-Substituted-2-Furaldehydes 61\u003c\/p\u003e \u003cp\u003e3.14 Preparation and Chemistry of 4-Coumarylzinc Bromide 73\u003c\/p\u003e \u003cp\u003e3.15 Preparation and Cross-Coupling of 2-Pyridyl and 3-Pyridylzinc Bromides 77\u003c\/p\u003e \u003cp\u003e3.16 Preparation of Functionalized α-Chloromethyl Ketones 106\u003c\/p\u003e \u003cp\u003e3.17 Rieke Zinc as a Reducing Agent for Common Organic Functional Groups 108\u003c\/p\u003e \u003cp\u003e3.18 Detailed Studies on the Mechanism of Organic Halide Oxidative Addition at a Zinc Metal Surface 111\u003c\/p\u003e \u003cp\u003e3.19 Regiocontrolled Synthesis of Poly(3-Alkylthiophenes) Mediated by Rieke Zinc: A New Class of Plastic Semiconductors 133\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Magnesium 161\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 General Background and Mechanistic Details of Grignard Reaction 161\u003c\/p\u003e \u003cp\u003e4.2 General Methods for Preparation of Rieke Magnesium 165\u003c\/p\u003e \u003cp\u003e4.3 Grignard Reagent Formation and Range of Reactivity of Magnesium 167\u003c\/p\u003e \u003cp\u003e4.4 1,3-Diene-Magnesium Complexes and Their Chemistry 172\u003c\/p\u003e \u003cp\u003e4.5 Regioselectivity of Reaction of Complexes with Electrophiles 173\u003c\/p\u003e \u003cp\u003e4.6 Carbocyclization of (1,4-Diphenyl-2-butene-1,4-diyl) magnesium with Organic Dihalides 175\u003c\/p\u003e \u003cp\u003e4.7 1,2-Dimethylenecycloalkane-Magnesium Reagents 175\u003c\/p\u003e \u003cp\u003e4.8 Synthesis of Fused Carbocycles, β-γ-Unsaturated Ketones, and 3-Cyclopentenols from Conjugated Diene-Magnesium Reagents 178\u003c\/p\u003e \u003cp\u003e4.9 Synthesis of Spiro-γ-Lactones and Spiro-δ-Lactones from 1,3-Diene-Magnesium Reagents 184\u003c\/p\u003e \u003cp\u003e4.10 Synthesis of γ-Lactams from Conjugated Diene-Magnesium Reagents 190\u003c\/p\u003e \u003cp\u003e4.11 Low-Temperature Grignard Chemistry 192\u003c\/p\u003e \u003cp\u003e4.12 Typical Procedures for Preparation of Active Magnesium and Typical Grignard Reactions as Well as 1,3-Diene Chemistry 197\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Copper 209\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Background of Copper and Organocopper Chemistry 209\u003c\/p\u003e \u003cp\u003e5.2 Development of Rieke Copper 210\u003c\/p\u003e \u003cp\u003e5.3 Phosphine-Based Copper 211\u003c\/p\u003e \u003cp\u003e5.4 Lithium 2-Thienylcyanocuprate-Based Copper 220\u003c\/p\u003e \u003cp\u003e5.5 Copper Cyanide-Based Active Copper 224\u003c\/p\u003e \u003cp\u003e5.6 Formal Copper Anion Preparation and Resulting Chemistry 228\u003c\/p\u003e \u003cp\u003e5.7 Typical Experimental Details of Copper Chemistry 232\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Indium 241\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Background and Synthesis of Rieke Indium 241\u003c\/p\u003e \u003cp\u003e6.2 Preparation of Organoindium Compounds 241\u003c\/p\u003e \u003cp\u003e6.3 Preparation and Reactions of Indium Reformatsky Reagents 246\u003c\/p\u003e \u003cp\u003e6.4 Experimental Details for Preparation and Reactions of Activated Indium 250\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Nickel 255\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Preparation of Rieke Nickel, Characterization of Active Nickel Powder, and Some Chemistry 255\u003c\/p\u003e \u003cp\u003e7.2 Preparation of 3-Aryl-2-hydroxy-1-propane by Nickel-Mediated Addition of Benzylic Halides to 1,2-Diketones 261\u003c\/p\u003e \u003cp\u003e7.3 Preparation of 3-Arylpropanenitriles by Nickel-Mediated Reaction of Benzylic Halides with Haloacetonitriles 265\u003c\/p\u003e \u003cp\u003e7.4 Reformatsky-Type Additions of Haloacetonitriles to Aldehydes Mediated by Metallic Nickel 267\u003c\/p\u003e \u003cp\u003e7.5 Preparation of Symmetrical 1,3-Diarylpropan-2-ones from Benzylic Halides and Alkyl Oxalyl Chlorides 269\u003c\/p\u003e \u003cp\u003e7.6 Nickel-Mediated Coupling of Benzylic Halides and Acyl Halides to Yield Benzyl Ketones 273\u003c\/p\u003e \u003cp\u003e7.7 Nickel-Assisted Room Temperature Generation and Diels–Alder Chemistry of o-Xylylene Intermediates 275\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Manganese 305\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Preparation of Rieke Manganese 305\u003c\/p\u003e \u003cp\u003e8.2 Direct Formation of Aryl-, Alkyl-, and Vinylmanganese Halides Oxidative Addition of the Active Metal to the Corresponding Halide 306\u003c\/p\u003e \u003cp\u003e8.3 Direct Formation of Organomanganese Tosylates and Mesylates and Some Cross-Coupling Reactions 316\u003c\/p\u003e \u003cp\u003e8.4 Benzylic Manganese Halides, Sulfonates, and Phosphates: Preparation, Coupling Reactions, and Applications in New Reactions 320\u003c\/p\u003e \u003cp\u003e8.5 Preparation and Coupling Reactions of Thienylmanganese Halides 339\u003c\/p\u003e \u003cp\u003e8.6 Synthesis of β-Hydroxy Esters Using Active Manganese 343\u003c\/p\u003e \u003cp\u003e8.7 Reductive Coupling of Carbonyl-Containing Compounds and Imines Using Reactive Manganese 347\u003c\/p\u003e \u003cp\u003e8.8 Preparation of Heteroarylmanganese Reagents and Their Cross-Coupling Chemistry 355\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Calcium 371\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Preparation of Rieke Calcium 371\u003c\/p\u003e \u003cp\u003e9.2 Oxidative Addition Reactions of Rieke Calcium with Organic Halides and Some Subsequent Reactions 372\u003c\/p\u003e \u003cp\u003e9.3 Preparation and Reaction of Calcium Cuprate Reagents 373\u003c\/p\u003e \u003cp\u003e9.4 Preparation and Reactions of Calcium Metallocycles 377\u003c\/p\u003e \u003cp\u003e9.5 Synthesis of Polyphenylcarbynes Using Highly Reactive Calcium, Barium, and Strontium: A Precursor for\u003c\/p\u003e \u003cp\u003e9.6 Chemical Modification of Halogenated Polystyrenes Using Rieke Calcium or Rieke Copper 386\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Barium 391\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Preparation of Rieke Barium 391\u003c\/p\u003e \u003cp\u003e10.2 Oxidative Addition of Rieke Barium to Allylic Halides: Preparation of Stereochemically Homogeneous Allylic Barium Reagents 392\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Iron 395\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Preparation of Highly Reactive Iron and Some Oxidative Addition Chemistry 395\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Palladium and Platinum 399\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Preparation of Highly Reactive Palladium and Platinum and Some Oxidative Addition Chemistry 399\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Highly Reactive Uranium and Thorium 407\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Two Methods for Preparation of Highly Reactive Uranium and Thorium: Use of a Novel Reducing Agent Naphthalene Dianion 407\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Aluminum 425\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Preparation of Highly Reactive Aluminum and Reaction with Aryl Halides 425\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Cobalt 429\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Two Methods for Preparing Rieke Cobalt: Reaction with CO and Also Fischer–Tropsch Chemistry 429\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Chromium 443\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Preparation of Highly Reactive Chromium Metal and Its Reaction with CO to Yield Cr(CO)6 443\u003c\/p\u003e \u003cp\u003eReferences 446\u003c\/p\u003e \u003cp\u003eIndex 447\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default 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