{"product_id":"carbon-dots-as-theranostic-agents-9781119460107","title":"Carbon Dots As Theranostic Agents","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book is designed for researchers and students interested in carbon dots applications in health care, especially as a theranostic agent.    Carbon Dots as Theranostic Agents focuses on the fundamental understanding along with the applications of this unique fluorescent nano-biomachine. The book begins with the explanation that carbon dots fall between the usual daily macro or bulk physics and the quantum mechanics and covers their unique properties like quantum mechanics and quantum confinement. It then encompasses the domain of various physical, chemical and biological methods that efficiently synthesizes the carbon dots and their desired properties. The basic characterization techniques used for carbon dots is also covered in this book. Conjugation of carbon dots with different moieties is another aspect that enhances its applications, hence this is highlighted too. The book also details how to maneuver the carbon dots for their use in targeted drug delivery with emphasis on canc\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1. Carbon Dots: Discovery, Synthesis and Characterization 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1. Background 1\u003c\/p\u003e \u003cp\u003e1.2. Introduction to QD 2\u003c\/p\u003e \u003cp\u003e1.2.1. What is Quantum Mechanics? 4\u003c\/p\u003e \u003cp\u003e1.2.2. Quantum Confinement 7\u003c\/p\u003e \u003cp\u003e1.2.3. Discovery and History of Carbon Dots 8\u003c\/p\u003e \u003cp\u003e1.3. Carbon QD and Graphene QD 9\u003c\/p\u003e \u003cp\u003e1.4. Various Methods of Synthesis of Carbon Dots 10\u003c\/p\u003e \u003cp\u003e1.4.1. Electrochemical Methods 11\u003c\/p\u003e \u003cp\u003e1.4.2. Combustion and Thermal Oxidation Method 13\u003c\/p\u003e \u003cp\u003e1.4.3. Hydrothermal Oxidation Method 15\u003c\/p\u003e \u003cp\u003e1.4.4. Solvothermal Method 18\u003c\/p\u003e \u003cp\u003e1.4.5. Laser Ablation of Graphite 18\u003c\/p\u003e \u003cp\u003e1.4.6. Pulsed Laser Irradiation of Carbon Source 20\u003c\/p\u003e \u003cp\u003e1.4.7. Arc Discharge Method 20\u003c\/p\u003e \u003cp\u003e1.4.8. Plasma Treatment 21\u003c\/p\u003e \u003cp\u003e1.4.9. Opening of Fullerene Cage 22\u003c\/p\u003e \u003cp\u003e1.4.10. Ultrasonication Method 22\u003c\/p\u003e \u003cp\u003e1.4.11. Microwave-Assisted Method 23\u003c\/p\u003e \u003cp\u003e1.4.12. Chemical Methods 26\u003c\/p\u003e \u003cp\u003e1.4.13. Supported Synthetic Procedure 26\u003c\/p\u003e \u003cp\u003e1.4.14. Biogenic Method 28\u003c\/p\u003e \u003cp\u003e1.5. Characterization of Carbon Dots 31\u003c\/p\u003e \u003cp\u003e1.5.1. Microscopic Methods 32\u003c\/p\u003e \u003cp\u003e1.5.1.1. SEM and TEM Characterization 32\u003c\/p\u003e \u003cp\u003e1.5.1.2. AFM and STM Characterization 34\u003c\/p\u003e \u003cp\u003e1.5.2. Spectroscopic Methods 35\u003c\/p\u003e \u003cp\u003e1.5.2.1. UV-Vis Spectroscopy and its Application for Band Gap Determination 37\u003c\/p\u003e \u003cp\u003e1.5.2.2. Fluorescence Spectrometry 37\u003c\/p\u003e \u003cp\u003e1.5.2.3. Fourier Transform Infrared (FTIR) Spectroscopy 38\u003c\/p\u003e \u003cp\u003e1.5.2.4. X-Ray Diffraction (XRD) Analysis 40\u003c\/p\u003e \u003cp\u003e1.5.2.5. X-Ray Photoelectron Spectroscopy (XPS) 41\u003c\/p\u003e \u003cp\u003e1.5.2.6. Dynamic Light Scattering\/Photon Correlation Spectroscopy (DLS\/PCS) 41\u003c\/p\u003e \u003cp\u003e1.5.2.7. Dual Polarization Interferometry (DPI) 42\u003c\/p\u003e \u003cp\u003e1.5.2.8. Raman Spectroscopy 43\u003c\/p\u003e \u003cp\u003e1.5.2.9. Nuclear Magnetic Resonance (NMR) Spectroscopy 44\u003c\/p\u003e \u003cp\u003e1.6. Summary 45\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2. Properties of Carbon Dots 47\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1. Introduction 47\u003c\/p\u003e \u003cp\u003e2.2. Optical Properties 49\u003c\/p\u003e \u003cp\u003e2.2.1. Absorbance 51\u003c\/p\u003e \u003cp\u003e2.2.2. Photo-Induced Electron Transfer (PET) with CDs 52\u003c\/p\u003e \u003cp\u003e2.2.3. Fluorescence\/Photoluminescence (PL) 53\u003c\/p\u003e \u003cp\u003e2.2.3.1. Multiphoton Excitation 60\u003c\/p\u003e \u003cp\u003e2.2.3.2. Upconversion Photoluminescence 61\u003c\/p\u003e \u003cp\u003e2.2.3.3. Lack of Blinking 63\u003c\/p\u003e \u003cp\u003e2.2.3.4. Resistance to Photobleaching 64\u003c\/p\u003e \u003cp\u003e2.2.4. Photocatalytic Property 65\u003c\/p\u003e \u003cp\u003e2.3. Chemically Inert 67\u003c\/p\u003e \u003cp\u003e2.4. Easy Functionalization 67\u003c\/p\u003e \u003cp\u003e2.5. Water Solubility 68\u003c\/p\u003e \u003cp\u003e2.6. Low Toxicity 68\u003c\/p\u003e \u003cp\u003e2.7. Biocompatibility 69\u003c\/p\u003e \u003cp\u003e2.8. Summary 70\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3. Carbon Dots and Conjugates 71\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1. Introduction 71\u003c\/p\u003e \u003cp\u003e3.2. Why Conjugation of Carbon Dots? 74\u003c\/p\u003e \u003cp\u003e3.3. Types of Carbon Dot Conjugates and Their Applications 76\u003c\/p\u003e \u003cp\u003e3.3.1. Biogenic Compounds Conjugated with Carbon Dots 77\u003c\/p\u003e \u003cp\u003e3.3.1.1. CDs Conjugated with Proteins\/Peptides 78\u003c\/p\u003e \u003cp\u003e3.3.1.2. CD Conjugates of Amino: Carboxylic Acid Ratio 80\u003c\/p\u003e \u003cp\u003e3.3.1.3. CDs Conjugated with DNA 80\u003c\/p\u003e \u003cp\u003e3.3.1.4. CDs Conjugated with RNase and SiRNA 84\u003c\/p\u003e \u003cp\u003e3.3.1.5. CDs Conjugated with Lipid 86\u003c\/p\u003e \u003cp\u003e3.3.1.6. CDs Conjugated with Folic Acid 86\u003c\/p\u003e \u003cp\u003e3.3.1.7. CDs Conjugated with Chitosan 88\u003c\/p\u003e \u003cp\u003e3.3.1.8. CDs Conjugated with Digitonin 89\u003c\/p\u003e \u003cp\u003e3.3.2. Inorganic Heteroatoms Conjugated with CDs 90\u003c\/p\u003e \u003cp\u003e3.3.2.1. CDs Conjugated with Gold Nanoparticles 91\u003c\/p\u003e \u003cp\u003e3.3.2.2. CDs Conjugated with Silica 92\u003c\/p\u003e \u003cp\u003e3.3.2.3. CDs Conjugated with ZnO 94\u003c\/p\u003e \u003cp\u003e3.3.2.4. CDs Conjugated with CdS 95\u003c\/p\u003e \u003cp\u003e3.3.2.5. CDs Conjugated with Strontium Oxide 96\u003c\/p\u003e \u003cp\u003e3.3.2.6. CDs Conjugated with Gadolinium(III) 97\u003c\/p\u003e \u003cp\u003e3.3.2.7. CDs Conjugated with Europium 97\u003c\/p\u003e \u003cp\u003e3.3.2.8. CDs Conjugated\/Doped with Nitrogen, Sulphur, Phosphorus and Boron 99\u003c\/p\u003e \u003cp\u003e3.3.3. Carbon Dots Conjugated with Organic Material 100\u003c\/p\u003e \u003cp\u003e3.3.3.1. PEG (Polyethylene Glycol) 101\u003c\/p\u003e \u003cp\u003e3.3.3.2. CDs Conjugated with PEI (Polyethylenimin) or Polyaziridine 102\u003c\/p\u003e \u003cp\u003e3.3.3.3. CDs Conjugated with α-Cyclodextrin 105\u003c\/p\u003e \u003cp\u003e3.3.3.4. CDs Conjugated with Cysteamine 106\u003c\/p\u003e \u003cp\u003e3.3.3.5. CDs Conjugated with Dihydrolipoic Acid 106\u003c\/p\u003e \u003cp\u003e3.3.3.6. CDs Conjugated with Polyamidoamine (PAMAM) Dendrimers 107\u003c\/p\u003e \u003cp\u003e3.3.3.7. CDs Covalently Conjugated with Rhodamine B Dyes 108\u003c\/p\u003e \u003cp\u003e3.3.3.8. CDs Conjugated with Fe–Aminoclay (FeAC) 109\u003c\/p\u003e \u003cp\u003e3.3.3.9. CDs Conjugated with MWCNT 109\u003c\/p\u003e \u003cp\u003e3.3.4. CDs Conjugated with Antibiotics 110\u003c\/p\u003e \u003cp\u003e3.3.4.1. CDs Conjugated with Ciprofloxacin 111\u003c\/p\u003e \u003cp\u003e3.3.4.2. CDs Conjugated with Tetracycline 114\u003c\/p\u003e \u003cp\u003e3.3.4.3. CDs Conjugated with Vancomycin 114\u003c\/p\u003e \u003cp\u003e3.3.4.4. CDs Conjugated with Ampicillin 115\u003c\/p\u003e \u003cp\u003e3.3.4.5. CDs Conjugated with Streptomycin 116\u003c\/p\u003e \u003cp\u003e3.3.5. CDs Conjugated with Anti-Neurodegenerative Drugs for Delivery to Central Nervous System 118\u003c\/p\u003e \u003cp\u003e3.3.5.1. CDs Conjugated with Haloperidol 119\u003c\/p\u003e \u003cp\u003e3.3.5.2. CDs Conjugated with Transferrin 124\u003c\/p\u003e \u003cp\u003e3.3.5.3. CDs Conjugated with Curcumin 125\u003c\/p\u003e \u003cp\u003e3.3.6. CDs Conjugated with Anticancer Drugs 128\u003c\/p\u003e \u003cp\u003e3.3.6.1. CDs Conjugated with Doxorubicin 128\u003c\/p\u003e \u003cp\u003e3.3.6.2. CDs Conjugated with Cisplatin 130\u003c\/p\u003e \u003cp\u003e3.4. Summary 132\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4. CD as Drug Delivery Vehicle 133\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1. Introduction 133\u003c\/p\u003e \u003cp\u003e4.2. Considerations in Using CD as Drug Delivery Vehicle 136\u003c\/p\u003e \u003cp\u003e4.3. Designs of CD-Based Drug Delivery System 137\u003c\/p\u003e \u003cp\u003e4.3.1. Designing for Water-Insoluble Drugs 138\u003c\/p\u003e \u003cp\u003e4.3.2. Designing for Targeting Tumor Location 138\u003c\/p\u003e \u003cp\u003e4.3.3. Designing a Theranostic Nanomedicine 139\u003c\/p\u003e \u003cp\u003e4.3.4. Designing a Photoresponsive Nzzano Drug Delivery System 139\u003c\/p\u003e \u003cp\u003e4.3.5. Designing for Gene Delivery 140\u003c\/p\u003e \u003cp\u003e4.3.6. Designing for Antibiotics Delivery 141\u003c\/p\u003e \u003cp\u003e4.4. Carbon Dots for Delivery of Anti-Cancer Drug 142\u003c\/p\u003e \u003cp\u003e4.4.1. A Brief Introduction to Cancer 143\u003c\/p\u003e \u003cp\u003e4.4.2. Necessity of Drug Targeting in Cancer Therapy 144\u003c\/p\u003e \u003cp\u003e4.4.3. Targeting Angiogenesis with CD 144\u003c\/p\u003e \u003cp\u003e4.4.4. Various CD Conjugates for Delivering Anti-Cancer Drug 145\u003c\/p\u003e \u003cp\u003e4.4.5. CD for pH-Dependent Drug Release 146\u003c\/p\u003e \u003cp\u003e4.4.6. CD for Drug Delivery to Renal Cancer 147\u003c\/p\u003e \u003cp\u003e4.4.7. CD for Drug Delivery to Lung Cancer 148\u003c\/p\u003e \u003cp\u003e4.4.8. CD for Drug Delivery to Breast Cancer 149\u003c\/p\u003e \u003cp\u003e4.5. CD for Drug Delivery to Neurodegenerative Disease 150\u003c\/p\u003e \u003cp\u003e4.6. CD for Gene Therapy 151\u003c\/p\u003e \u003cp\u003e4.7. CD to Monitor Delivery of SiRNA 152\u003c\/p\u003e \u003cp\u003e4.8. Challenges in Using CD as Drug Delivery Vehicle 152\u003c\/p\u003e \u003cp\u003e4.8.1. Prevention of Drug from Biological Degradation 153\u003c\/p\u003e \u003cp\u003e4.8.2. Effective Targeting 154\u003c\/p\u003e \u003cp\u003e4.8.3. Patient Compliance 155\u003c\/p\u003e \u003cp\u003e4.8.4. Cost Effectiveness 155\u003c\/p\u003e \u003cp\u003e4.9. Suitability of CD-Conjugated Drugs 156\u003c\/p\u003e \u003cp\u003e4.9.1. For Oral Drug Delivery 156\u003c\/p\u003e \u003cp\u003e4.9.2. By Inhalation 156\u003c\/p\u003e \u003cp\u003e4.9.3. As Transdermal Drug Delivery 157\u003c\/p\u003e \u003cp\u003e4.9.4. As Injection 157\u003c\/p\u003e \u003cp\u003e4.10. Summary 157\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5\u003c\/b\u003e\u003cb\u003e. \u003c\/b\u003e\u003cb\u003eCarbon Dots for Cell Imaging and Diagnostics 159\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1. Introduction 159\u003c\/p\u003e \u003cp\u003e5.2. Bioimaging 162\u003c\/p\u003e \u003cp\u003e5.2.1. Bioimaging of Cancerous Cells 166\u003c\/p\u003e \u003cp\u003e5.2.1.1. HeLa Cells 168\u003c\/p\u003e \u003cp\u003e5.2.1.2\u003cb\u003e. \u003c\/b\u003eHuman Breast Cancer MCF-7 Cells and Human Breast Tumor Cells MDA-MB-468 170\u003c\/p\u003e \u003cp\u003e5.2.1.3\u003cb\u003e. \u003c\/b\u003eB16F11 and HEK293 Cells 171\u003c\/p\u003e \u003cp\u003e5.2.1.4\u003cb\u003e. \u003c\/b\u003eEhrlich Ascites Carcinoma (EAC) Cells 173\u003c\/p\u003e \u003cp\u003e5.2.1.5\u003cb\u003e. \u003c\/b\u003eHuman U87 Cell 173\u003c\/p\u003e \u003cp\u003e5.2.1.6\u003cb\u003e. \u003c\/b\u003eMGC-803 Human Gastric Cancer Cells 174\u003c\/p\u003e \u003cp\u003e5.2.1.7\u003cb\u003e. \u003c\/b\u003eA549 Adenocarcinomic Human Alveolar (Lung) Basal Epithelial Cells 175\u003c\/p\u003e \u003cp\u003e5.2.1.8\u003cb\u003e. \u003c\/b\u003eHuman Hepatocellular Carcinoma Cells 175\u003c\/p\u003e \u003cp\u003e5.2.1.9\u003cb\u003e. \u003c\/b\u003eKidney Proximal Tubule Cell Line(LLC-PK1) 176\u003c\/p\u003e \u003cp\u003e5.2.1.10\u003cb\u003e. \u003c\/b\u003eC6 Glioma Cells 177\u003c\/p\u003e \u003cp\u003e5.2.2\u003cb\u003e. \u003c\/b\u003eBioimaging of Nucleus 178\u003c\/p\u003e \u003cp\u003e5.2.3\u003cb\u003e. \u003c\/b\u003eBioimaging of Virus 180\u003c\/p\u003e \u003cp\u003e5.2.4\u003cb\u003e. \u003c\/b\u003eBioimaging of Bacteria 181\u003c\/p\u003e \u003cp\u003e5.2.5\u003cb\u003e. \u003c\/b\u003eBioimaging of Drosophila melanogaster 183\u003c\/p\u003e \u003cp\u003e5.3\u003cb\u003e. \u003c\/b\u003eCDs as Sensor 184\u003c\/p\u003e \u003cp\u003e5.3.1\u003cb\u003e. \u003c\/b\u003eIntracellular Detection of Ions 185\u003c\/p\u003e \u003cp\u003e5.3.1.1\u003cb\u003e. \u003c\/b\u003eDetection of Ag Ions 185\u003c\/p\u003e \u003cp\u003e5.3.1.2\u003cb\u003e. \u003c\/b\u003eCD for Detection of Cu Ion 187\u003c\/p\u003e \u003cp\u003e5.3.1.3\u003cb\u003e. \u003c\/b\u003eDetection of Fe3+ Ions 190\u003c\/p\u003e \u003cp\u003e5.3.1.4\u003cb\u003e. \u003c\/b\u003eDetection of Hg2+ Ions 191\u003c\/p\u003e \u003cp\u003e5.3.2\u003cb\u003e. \u003c\/b\u003eDetection of Small Molecules 192\u003c\/p\u003e \u003cp\u003e5.3.2.1\u003cb\u003e. \u003c\/b\u003eDetection of Nitric Oxide 193\u003c\/p\u003e \u003cp\u003e5.3.2.2\u003cb\u003e. \u003c\/b\u003eDetection of Phosphate 193\u003c\/p\u003e \u003cp\u003e5.3.2.3\u003cb\u003e. \u003c\/b\u003eDetection of Reactive Oxygen Species 194\u003c\/p\u003e \u003cp\u003e5.3.2.4\u003cb\u003e. \u003c\/b\u003eDetection of H2S 194\u003c\/p\u003e \u003cp\u003e5.3.2.5\u003cb\u003e. \u003c\/b\u003eDetection of TNT 195\u003c\/p\u003e \u003cp\u003e5.3.2.6\u003cb\u003e. \u003c\/b\u003eDetection of Hydroquinone 195\u003c\/p\u003e \u003cp\u003e5.3.2.7\u003cb\u003e. \u003c\/b\u003eDetection of Surfactant 196\u003c\/p\u003e \u003cp\u003e5.3.2.8\u003cb\u003e. \u003c\/b\u003eDetection of Humidity 197\u003c\/p\u003e \u003cp\u003e5.3.3\u003cb\u003e. \u003c\/b\u003eDetection of Biological pH Value 198\u003c\/p\u003e \u003cp\u003e5.3.4\u003cb\u003e. \u003c\/b\u003eDetection of Nucleic Acid 200\u003c\/p\u003e \u003cp\u003e5.3.5\u003cb\u003e. \u003c\/b\u003eDetection of Vitamins 201\u003c\/p\u003e \u003cp\u003e5.3.6\u003cb\u003e. \u003c\/b\u003eDetection of Protein and Enzymes 202\u003c\/p\u003e \u003cp\u003e5.3.7\u003cb\u003e. \u003c\/b\u003eDetection of Glucose 202\u003c\/p\u003e \u003cp\u003e5.3.8\u003cb\u003e. \u003c\/b\u003eDetection of Cancerous Cells 203\u003c\/p\u003e \u003cp\u003e5.3.9\u003cb\u003e. \u003c\/b\u003eDetection of Dopamine Neurotransmitter 204\u003c\/p\u003e \u003cp\u003e5.4\u003cb\u003e. \u003c\/b\u003eConcluding Remarks 206\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6\u003c\/b\u003e\u003cb\u003e. \u003c\/b\u003e\u003cb\u003eSuitability of Carbon Dots as Payload for Plants 209\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1. Introduction 209\u003c\/p\u003e \u003cp\u003e6.2. Suitability of Carbon Dots as a Payload for Plant 211\u003c\/p\u003e \u003cp\u003e6.2.1. Cytotoxicity of Carbon Dots 212\u003c\/p\u003e \u003cp\u003e6.2.2. Carbon Dots and Plant Growth 213\u003c\/p\u003e \u003cp\u003e6.2.2.1. Wheat 215\u003c\/p\u003e \u003cp\u003e6.2.2.2. Green Beans 215\u003c\/p\u003e \u003cp\u003e6.2.3. Is Cell Wall a Barrier for Carbon Dot Internalization? 216\u003c\/p\u003e \u003cp\u003e6.2.4\u003cb\u003e. \u003c\/b\u003eOther Possible Routes for Entry of Carbon Dots 219\u003c\/p\u003e \u003cp\u003e6.3\u003cb\u003e. \u003c\/b\u003eCarbon Dots and Plant Fertilizer 221\u003c\/p\u003e \u003cp\u003e6.3.1\u003cb\u003e. \u003c\/b\u003eNitrogen 222\u003c\/p\u003e \u003cp\u003e6.3.2\u003cb\u003e. \u003c\/b\u003ePhosphorus 224\u003c\/p\u003e \u003cp\u003e6.3.3\u003cb\u003e. \u003c\/b\u003ePotassium 225\u003c\/p\u003e \u003cp\u003e6.3.4\u003cb\u003e. \u003c\/b\u003eMicronutrients 226\u003c\/p\u003e \u003cp\u003e6.4\u003cb\u003e. \u003c\/b\u003eNeed for Sensor to Detect 227\u003c\/p\u003e \u003cp\u003e6.4.1\u003cb\u003e. \u003c\/b\u003ePlant Nutrient Status 228\u003c\/p\u003e \u003cp\u003e6.4.2\u003cb\u003e. \u003c\/b\u003eWater 229\u003c\/p\u003e \u003cp\u003e6.4.3\u003cb\u003e. \u003c\/b\u003ePathological Status of Plant 231\u003c\/p\u003e \u003cp\u003e6.4.4\u003cb\u003e. \u003c\/b\u003eResidual Pesticide, Herbicide or Insecticide in Plants 232\u003c\/p\u003e \u003cp\u003e6.5\u003cb\u003e. \u003c\/b\u003eCarbon Dots and Foliar Application of Drugs on Plants 233\u003c\/p\u003e \u003cp\u003e6.5.1\u003cb\u003e. \u003c\/b\u003eCuticular Layer 233\u003c\/p\u003e \u003cp\u003e6.5.2\u003cb\u003e. \u003c\/b\u003eCell Wall 235\u003c\/p\u003e \u003cp\u003e6.5.3\u003cb\u003e. \u003c\/b\u003ePlasma Membrane 235\u003c\/p\u003e \u003cp\u003e6.6\u003cb\u003e. \u003c\/b\u003eCarbon Dots as Trojan Horse to Penetrate Foliar Surface for Therapeutic Molecule Delivery 236\u003c\/p\u003e \u003cp\u003e6.6.1\u003cb\u003e. \u003c\/b\u003eCD for Delivery of Antibiotics to Plants 237\u003c\/p\u003e \u003cp\u003e6.7\u003cb\u003e. \u003c\/b\u003eConcluding Remarks 240\u003c\/p\u003e \u003cp\u003eReferences 241\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49407059624279,"sku":"9781119460107","price":146.66,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9781119460107.jpg?v=1730498030","url":"https:\/\/bookcurl.com\/products\/carbon-dots-as-theranostic-agents-9781119460107","provider":"Book Curl","version":"1.0","type":"link"}