{"product_id":"burgers-medicinal-chemistry-drug-discovery-and-development-8-volume-set-9781119530305","title":"Burgers Medicinal Chemistry Drug Discovery and Development 8 Volume Set","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e\u003cb\u003eBurger's Medicinal Chemistry, Drug Discovery and Development\u003c\/b\u003e \u003cp\u003e\u003cb\u003eExplore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe newly revised eighth edition of the eight-volume \u003ci\u003eBurger's Medicinal Chemistry, Drug Discovery and Development\u003c\/i\u003e is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures.\u003c\/p\u003e\u003cp\u003eAlong with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues t\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003ePREFACE OF THE EDITOR-IN-CHIEF\u003c\/p\u003e \u003cp\u003ePREFACE OF THE CONSULTING EDITOR\u003c\/p\u003e \u003cp\u003ePREFACE OF THE VOLUME EDITOR\u003c\/p\u003e \u003cp\u003eCONTRIBUTORS\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 1 : Methods in Drug Discovery\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Chirality and Drug Discovery\u003c\/p\u003e \u003cp\u003e2 Drug Discovery beyond the Rule of Five\u003c\/p\u003e \u003cp\u003e3 Microbes to Man: From Soils and the Depths to Drugs as of early 2019\u003c\/p\u003e \u003cp\u003e4 Fragment-Based Lead Discovery\u003c\/p\u003e \u003cp\u003e5 Recent Advances in Development, Validation, and Exploitation of QSAR Models\u003c\/p\u003e \u003cp\u003e6 Structure-Based Drug Design\u003c\/p\u003e \u003cp\u003e7 Docking, Scoring and Virtual Screening in Drug Discovery\u003c\/p\u003e \u003cp\u003e8 Computational Chemistry Tools\u003c\/p\u003e \u003cp\u003e9 Assay Development and High-Throughput Screening\u003c\/p\u003e \u003cp\u003e10 Advances in NMR-based Characterization of Drug Substances, Impurities, Degradants and Drug Metabolites\u003c\/p\u003e \u003cp\u003e11 NMR-Based Screening and Drug Discovery\u003c\/p\u003e \u003cp\u003e12 Mass Spectrometry and Drug Discovery\u003c\/p\u003e \u003cp\u003e13 Cryo Electron Microscopy in Drug Discovery and Development: Opportunities and Challenges\u003c\/p\u003e \u003cp\u003e14 Combinatorial Chemistry and Its Associated Technologies\u003c\/p\u003e \u003cp\u003e15 Recent Advances in Chemistry Technologies and Applications to Medicinal Chemistry\u003c\/p\u003e \u003cp\u003e16 Automated Synthesis\u003c\/p\u003e \u003cp\u003e17 Artificial Intelligence in Medicinal Chemistry\u003c\/p\u003e \u003cp\u003e18 Medicinal Chemical Biology\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 2 : Lead Discovery in Drug Discovery\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Ion Channels as Therapeutic Drug Targets  \u003c\/p\u003e \u003cp\u003e2 Drug Transport and Membrane Transport Proteins\u003c\/p\u003e \u003cp\u003e3 Structure-Based Drug Design for G Protein-Coupled Receptors\u003c\/p\u003e \u003cp\u003e4 Enzymes as Drug Targets\u003c\/p\u003e \u003cp\u003e5 Allosterism \u0026amp; Drug Discovery\u003c\/p\u003e \u003cp\u003e6 Nuclear Hormone Receptor Medicinal Chemistry\u003c\/p\u003e \u003cp\u003e7 ADMET In Vitro Profiling Utility and Applications in Lead Discovery\u003c\/p\u003e \u003cp\u003e8 Principles of Drug Metabolism\u003c\/p\u003e \u003cp\u003e9 Advances in Multiobjective Optimization for Drug Discovery and Development\u003c\/p\u003e \u003cp\u003e10 The Design and Application of Bioisosteres in Drug Design\u003c\/p\u003e \u003cp\u003e11 Structure Alerts in Medicinal Chemistry (original chapter: Structural Alerts for Toxicity)\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 3 : Development\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Intellectual Property for Biotechnology and Pharmaceutical Products\u003c\/p\u003e \u003cp\u003e2 Experiences in Academic and Industry Partnerships Forging a Path to Translational Drug Discovery\u003c\/p\u003e \u003cp\u003e3 Large-Scale Synthesis\u003c\/p\u003e \u003cp\u003e4 Preparative Chromatography for Production\u003c\/p\u003e \u003cp\u003e5 Translational Pharmaceutics and Early Phase Clinical Development\u003c\/p\u003e \u003cp\u003e6 Salt Screening and Selection\u003c\/p\u003e \u003cp\u003e7 Polymorphic Crystal Forms in Drug Delivery (Crystal Engineering)\u003c\/p\u003e \u003cp\u003e8 Physicochemical Characterization and Oral Dosage Form Design and Selection\u003c\/p\u003e \u003cp\u003e9 Prodrugs: Strategic Deployment, Metabolic Considerations, and Chemical Design Principles\u003c\/p\u003e \u003cp\u003e10 Provisional BCS Classification of Leading Oral Drugs in Global Market\u003c\/p\u003e \u003cp\u003e11 Process Development of Protein Therapeutics\u003c\/p\u003e \u003cp\u003e12 Role of Permeability in Drug ADME, PK Interactions and Toxicity\u003c\/p\u003e \u003cp\u003e13 Toxicology and Nonclinical Safety Assessment in Pharmaceutical Discovery and Development\u003c\/p\u003e \u003cp\u003e14 Quality Assurance  \u003c\/p\u003e \u003cp\u003e15 The FDA and Drug Regulatory Issues\u003c\/p\u003e \u003cp\u003e16 FDA-Approved Medicines\u003c\/p\u003e \u003cp\u003e17 Clinical Development - A Primer\u003c\/p\u003e \u003cp\u003e18 Global Health Outcomes and Real World Evidence a Primer\u003c\/p\u003e \u003cp\u003e19 A Brief Primer on Project Leadership, Project Management and Cross-Functional Teams\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 4 : Cardiovascular, Endocrine and Metabolic Diseases\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Dipeptidyl Peptidase 4 Inhibitors\u003c\/p\u003e \u003cp\u003e2 Glucagon Like Peptide 1 Receptor Activators\u003c\/p\u003e \u003cp\u003e3 Sodium Glucose Co-Transporter Inhibitors for the Treatment of Diabetes\u003c\/p\u003e \u003cp\u003e4 Treatments for Non-Alcoholic Steatohepatitis (NASH)\u003c\/p\u003e \u003cp\u003e5 Therapeutic Strategies for Sickle Cell Disease\u003c\/p\u003e \u003cp\u003e6 Hematopoietic Agents\u003c\/p\u003e \u003cp\u003e7 Anticoagulants\u003c\/p\u003e \u003cp\u003e8 Antiplatelet Agents (needs proofreading, few minor changes needs to be done by the author.\u003c\/p\u003e \u003cp\u003e9 Atherosclerosis: Cholesterol Management (original: Atherosclerosis I: LDL Cholesterol Lowering)\u003c\/p\u003e \u003cp\u003e10 Recent Advances Toward New Small Molecule Therapies for Heart Failure  \u003c\/p\u003e \u003cp\u003e11 ACE Inhibitors\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 5 : Inflammation, Pulmonary, Bone, Immunology Agents and Vitamins\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Fundamentals of Steroid Chemistry and Biochemistry\u003c\/p\u003e \u003cp\u003e2 Estrogen Receptor Modulators (original chapter: Female Sex Hormones, Contraceptives, And Fertility Drugs by Peter C. Ruenitz)\u003c\/p\u003e \u003cp\u003e3 Modulation of the Androgen Receptor Axis bmc055 (original chapter: Male Sex Hormones, Analogs, and Antagonists)\u003c\/p\u003e \u003cp\u003e4 Essential Micronutrients: Vitamins and Essential Fatty Acids\u003c\/p\u003e \u003cp\u003e5 Current and Emerging Therapies in Pulmonary Disease\u003c\/p\u003e \u003cp\u003e6 Anti-Inflammatory Glucocorticoids and Receptors\u003c\/p\u003e \u003cp\u003e7 Osteoporosis Therapy: Mechanistic Antiresorptives  \u003c\/p\u003e \u003cp\u003e8 Osteoporosis: Current and Future Anabolic Therapy\u003c\/p\u003e \u003cp\u003e9 Drug Discovery in Erectile Dysfunction and Sleep Disorders (original chapter: Drug Discovery in Non-Life-Threatening Disorders: Erectile Dysfunction, Insomnia, and Smoking)\u003c\/p\u003e \u003cp\u003e10 Multiple Sclerosis\u003c\/p\u003e \u003cp\u003e11 JAK Inhibitors for Autoimmune Diseases\u003c\/p\u003e \u003cp\u003e12 Eicosanoid Pathway Modulators: Prostaglandins, Prostacyclins and Thromboxanes\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 6 : Cancer\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Synthetic DNA Target Therapeutics\u003c\/p\u003e \u003cp\u003e2 USFDA-Approved Small-Molecule Kinase Inhibitors for Cancer Therapy (original chapter: Kinase Inhibitors: Approved Drugs and Clinical Candidates)\u003c\/p\u003e \u003cp\u003e3 Cancer Drug Resistance: Targets and Therapies\u003c\/p\u003e \u003cp\u003e4 Natural Products as Cytotoxic Agents\u003c\/p\u003e \u003cp\u003e5 Tumor Metabolism: Focused on Tumor Glycolysis, Progress and Prospects in Cancer Therapy\u003c\/p\u003e \u003cp\u003e6 Small-Molecule Effectors of DNA Repair Proteins: applications for development of cancer therapeutics and research  \u003c\/p\u003e \u003cp\u003e7 Angiogenesis Inhibitors\u003c\/p\u003e \u003cp\u003e8 Cancer Targets Involving the Ubiquitin Proteasome System\u003c\/p\u003e \u003cp\u003e9 Immuno-oncology\u003c\/p\u003e \u003cp\u003e10 The Design and Development of Antibody-Drug Conjugates (ADCs) for the Treatment of Cancer\u003c\/p\u003e \u003cp\u003e11 Hsp90 Inhibitors  \u003c\/p\u003e \u003cp\u003e12 Gene Therapy with Plasmid DNA\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 7 : Antiinfectives\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Confronting the COVID-19 Pandemic: December 2019 – May 2020\u003c\/p\u003e \u003cp\u003e2 Medicinal Chemistry of β-Lactam Antibiotics\u003c\/p\u003e \u003cp\u003e3 2010 to 2020: ten years of malaria drug discovery\u003c\/p\u003e \u003cp\u003e4 Drug Discovery and Development for Kinetoplastid Diseases  \u003c\/p\u003e \u003cp\u003e5 Anti-DNA Virus Agents\u003c\/p\u003e \u003cp\u003e6 Polymyxins as Antibacterials and Antibiotic Potentiators\u003c\/p\u003e \u003cp\u003e7 Antifungal Drugs  \u003c\/p\u003e \u003cp\u003e8 The Gut Microbiome\u003c\/p\u003e \u003cp\u003e9 Antitubercular Agents\u003c\/p\u003e \u003cp\u003e10 Bacterial Efflux Pumps and Their Inhibitors\u003c\/p\u003e \u003cp\u003e11 Current Status of Approaches to Eradicate HIV Infection\u003c\/p\u003e \u003cp\u003e12 Antiinfective Case Histories\u003c\/p\u003e \u003cp\u003e\u003cb\u003eVolume 8 : CNS\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Cholinergics\/Anticholinergics\u003c\/p\u003e \u003cp\u003e2 Therapeutic and Diagnostic Agents for Parkinson’s Disease\u003c\/p\u003e \u003cp\u003e3 Opioid Receptor Ligands\u003c\/p\u003e \u003cp\u003e4 Antipsychotic Agents  \u003c\/p\u003e \u003cp\u003e5 Antidepressants\u003c\/p\u003e \u003cp\u003e6 PET and SPECT in Drug Development\u003c\/p\u003e \u003cp\u003e7 New and Emerging Antiepileptic Drugs\u003c\/p\u003e \u003cp\u003e8 Cognition\u003c\/p\u003e \u003cp\u003e9 The Blood-brain Barrier and CNS Drug Delivery\u003c\/p\u003e \u003cp\u003eINDEX\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":53515638374743,"sku":"9781119530305","price":2999.66,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/bookcurl.com\/products\/burgers-medicinal-chemistry-drug-discovery-and-development-8-volume-set-9781119530305","provider":"Book Curl","version":"1.0","type":"link"}