{"product_id":"biomedical-mass-transport-and-chemical-reaction-9780471656326","title":"Biomedical Mass Transport and Chemical Reaction","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003e*        Presents complex material in an easy to understand progression of ideas.        *        Illustrates principles by example problems taken from physiology and medicine or design problems involving biomedical devices.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003e\u003cp\u003ePreface xvi\u003c\/p\u003e \u003cp\u003eGuidance to Instructors xvii\u003c\/p\u003e \u003cp\u003eMethods for Solving Model Equations xix\u003c\/p\u003e \u003cp\u003eAcknowledgments xx\u003c\/p\u003e \u003cp\u003eAbout the Companion Website xxi\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Introduction 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Biological Structure and Function 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Cell Energy Related to Whole-Body Function 4\u003c\/p\u003e \u003cp\u003e1.2 Tissue and Organ Systems 8\u003c\/p\u003e \u003cp\u003e1.3 Cell Structure and Energy Metabolism 16\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Modeling Concepts for Biological Mass Transport 21\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Representation of Biological Media 21\u003c\/p\u003e \u003cp\u003e2.2 Mechanisms of Mass Transport 25\u003c\/p\u003e \u003cp\u003e2.3 Formulation of Material Balances 30\u003c\/p\u003e \u003cp\u003e2.4 Spatially Lumped and Distributed Models 32\u003c\/p\u003e \u003cp\u003eReferences 39\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Thermodynamics of Biomedical Processes 41\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Basics of Equilibrium Thermodynamics 43\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Thermodynamic Systems and States 43\u003c\/p\u003e \u003cp\u003e3.2 Heat, Work, and the First Law 44\u003c\/p\u003e \u003cp\u003e3.3 Enthalpy and Heat Effects 45\u003c\/p\u003e \u003cp\u003e3.4 Entropy and the Second Law 46\u003c\/p\u003e \u003cp\u003e3.5 Gibbs Free Energy and Equilibrium 46\u003c\/p\u003e \u003cp\u003e3.6 Properties of the Chemical Potential 51\u003c\/p\u003e \u003cp\u003eReferences 53\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Interfacial and Membrane Equilibria 54\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Equilibrium Criterion 54\u003c\/p\u003e \u003cp\u003e4.2 Interfacial Equilibria 56\u003c\/p\u003e \u003cp\u003e4.3 Membrane Equilibria 62\u003c\/p\u003e \u003cp\u003e4.4 Electrical Double Layer 71\u003c\/p\u003e \u003cp\u003eReferences 75\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Chemical Reaction Equilibrium 76\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Equilibrium Criterion 76\u003c\/p\u003e \u003cp\u003e5.2 Equilibrium Coefficients 78\u003c\/p\u003e \u003cp\u003e5.3 Acid Dissociation 80\u003c\/p\u003e \u003cp\u003e5.4 Ligand–Receptor Binding 83\u003c\/p\u003e \u003cp\u003e5.5 Equilibrium Models of Blood Gas Content 90\u003c\/p\u003e \u003cp\u003eReferences 101\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Fundamentals of Rate Processes 103\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Nonequilibrium Thermodynamics and Transport Rates 105\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Transport Velocities and Fluxes 105\u003c\/p\u003e \u003cp\u003e6.2 Stefan–Maxwell Equation 109\u003c\/p\u003e \u003cp\u003e6.3 Diffusion of Uncharged Substances 111\u003c\/p\u003e \u003cp\u003e6.4 Diffusion of Electrolytes 116\u003c\/p\u003e \u003cp\u003e6.5 Transport across Membranes 117\u003c\/p\u003e \u003cp\u003eReferences 123\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Mechanisms and Models of Diffusion 124\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Transport Rates in Homogeneous Materials 125\u003c\/p\u003e \u003cp\u003e7.2 Diffusion Coefficients in Gases 125\u003c\/p\u003e \u003cp\u003e7.3 Diffusion Coefficients in Liquids 128\u003c\/p\u003e \u003cp\u003e7.4 Transport in Porous Media Models of Tissue 134\u003c\/p\u003e \u003cp\u003e7.5 Transport in Suspension Models of Tissue 144\u003c\/p\u003e \u003cp\u003eReferences 151\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Chemical Reaction Rates 152\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 General Kinetic Models 152\u003c\/p\u003e \u003cp\u003e8.2 Basis of Reaction Rate Equations 154\u003c\/p\u003e \u003cp\u003e8.3 Multi-Step Reactions 158\u003c\/p\u003e \u003cp\u003e8.4 Ligand–Receptor Kinetics 161\u003c\/p\u003e \u003cp\u003e8.5 Enzyme Kinetics 166\u003c\/p\u003e \u003cp\u003e8.6 Urea Cycle as a Reaction Network 173\u003c\/p\u003e \u003cp\u003eReferences 178\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Transport Models in Fluids and Membranes\u003c\/b\u003e \u003cb\u003e179\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Unidirectional Transport 181\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Unidirectional Transport Equations 181\u003c\/p\u003e \u003cp\u003e9.2 Steady-State Diffusion 186\u003c\/p\u003e \u003cp\u003e9.3 Diffusion with Parallel Convection 191\u003c\/p\u003e \u003cp\u003e9.4 Diffusion with Chemical Reaction 194\u003c\/p\u003e \u003cp\u003e9.5 Unsteady-State Diffusion 201\u003c\/p\u003e \u003cp\u003eReferences 203\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Membrane Transport I: Convection and Diffusion Processes 204\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Ordinary Diffusion 204\u003c\/p\u003e \u003cp\u003e10.2 Diffusion with Parallel Convection 211\u003c\/p\u003e \u003cp\u003e10.3 Cell Membrane Channels 216\u003c\/p\u003e \u003cp\u003eReferences 223\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Membrane Transport II: Carrier-Mediated Processes 224\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Facilitated Transport of a Single Substance 224\u003c\/p\u003e \u003cp\u003e11.2 Cotransport of Two Substrates 227\u003c\/p\u003e \u003cp\u003e11.3 Simulation of Tracer Experiments 230\u003c\/p\u003e \u003cp\u003e11.4 Primary Active Transport 237\u003c\/p\u003e \u003cp\u003e11.5 Electrical Effects on Ion Transport 242\u003c\/p\u003e \u003cp\u003eReferences 244\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Mass Transfer Coefficients and Chemical Separation Devices 245\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Transport Through a Single Phase 245\u003c\/p\u003e \u003cp\u003e12.2 Transport Through Multiple Phases 256\u003c\/p\u003e \u003cp\u003e12.3 Design and Performance of Separation Devices 265\u003c\/p\u003e \u003cp\u003eReferences 279\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V Multidimensional Processes of Molecules and Cells 281\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Fluid Mechanics I: Basic Concepts 283\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.2 Mechanical Properties and Rheology of Fluids 289\u003c\/p\u003e \u003cp\u003e13.3 Model Formulation and Scaling of Fluid Flow 293\u003c\/p\u003e \u003cp\u003e13.4 Steady Flow Through A Tube 299\u003c\/p\u003e \u003cp\u003eReferences 306\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Fluid Mechanics II: Complex Flows 307\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Boundary Layer Flows 307\u003c\/p\u003e \u003cp\u003e14.2 Creeping Flow Through a Leaky Tube 319\u003c\/p\u003e \u003cp\u003e14.3 Periodic Flow Along a Tube 323\u003c\/p\u003e \u003cp\u003eReference 329\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Mass Transport I: Basic Concepts and Nonreacting Systems 330\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Three-Dimensional Mass Balances 330\u003c\/p\u003e \u003cp\u003e15.2 Special Cases 332\u003c\/p\u003e \u003cp\u003e15.3 One-Dimensional Transport Equations 334\u003c\/p\u003e \u003cp\u003e15.4 Model Formulation and Scaling of Mass Transport 339\u003c\/p\u003e \u003cp\u003e15.5 Diffusion and Convection in Nonreacting Systems 344\u003c\/p\u003e \u003cp\u003eReferences 357\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Mass Transport II: Chemical Reacting Systems 358\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Single-Phase Processes 358\u003c\/p\u003e \u003cp\u003e16.2 Multiphase Processes 368\u003c\/p\u003e \u003cp\u003e16.3 Processes with Interfacial Reaction 380\u003c\/p\u003e \u003cp\u003eReferences 387\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Cell Population Dynamics 388\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17.1 Cell Number Balances 388\u003c\/p\u003e \u003cp\u003e17.2 Cell Transport and Fate Processes 389\u003c\/p\u003e \u003cp\u003e17.3 Single Cell Population Dynamics 394\u003c\/p\u003e \u003cp\u003e17.4 Multiple Cell Population Dynamics 399\u003c\/p\u003e \u003cp\u003eReference 409\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VI Compartmental Modeling 411\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Compartment Models I: Basic Concepts and Tracer Analysis 413\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18.1 Compartmental Modeling Concepts 413\u003c\/p\u003e \u003cp\u003e18.2 Multiple-Compartment Models 421\u003c\/p\u003e \u003cp\u003e18.3 Nonideal Inputs and Moment Analysis 430\u003c\/p\u003e \u003cp\u003eReference 438\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Compartment Models II: Analysis of Physiological Systems 439\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e19.1 Open-Loop Models 439\u003c\/p\u003e \u003cp\u003e19.1.1 Multipool Model of Glucose Metabolism 439\u003c\/p\u003e \u003cp\u003e19.2 Models with Feedback and Recirculation 452\u003c\/p\u003e \u003cp\u003eReferences 466\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart VII Advanced Biomedical Applications 467\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Therapies for Tissue and Organ Dysfunction 469\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e20.1 Dynamics of Urea Clearance in a Patient During Hemodialysis 469\u003c\/p\u003e \u003cp\u003e20.2 Hemodialyzer Performance with Varying Filtration 474\u003c\/p\u003e \u003cp\u003e20.3 Gas Exchange in an Intravascular Lung Device 480\u003c\/p\u003e \u003cp\u003e20.4 Separation of Blood Components by Apheresis 486\u003c\/p\u003e \u003cp\u003e20.5 Epidermal Regeneration in Tissue-Engineered Skin 490\u003c\/p\u003e \u003cp\u003eReferences 497\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Drug Release, Delivery, and Distribution 498\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e21.1 Drug Release From an Agglomerated Tablet 498\u003c\/p\u003e \u003cp\u003e21.2 Drug Release From an Osmotic Pump Device 504\u003c\/p\u003e \u003cp\u003e21.3 Intestinal Drug Transport 509\u003c\/p\u003e \u003cp\u003e21.4 Drug Distribution in Ablated Tissues 515\u003c\/p\u003e \u003cp\u003e21.5 Intracranial Drug Delivery and Distribution 520\u003c\/p\u003e \u003cp\u003e21.6 Whole-Body Methotrexate Distribution 526\u003c\/p\u003e \u003cp\u003eReferences 534\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Diagnostics and Sensing 535\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e22.1 Chemical Monitoring of Tissue by Microdialysis 535\u003c\/p\u003e \u003cp\u003e22.2 Dual-Electrode Measurement of Blood Flow and Oxygen 541\u003c\/p\u003e \u003cp\u003e22.3 Detection of Ethanol in Blood from Exhaled Gas 546\u003c\/p\u003e \u003cp\u003e22.4 Oxygen Uptake and Utilization in Exercising Muscle 552\u003c\/p\u003e \u003cp\u003e22.5 Tracer Analysis with Pet Imaging 562\u003c\/p\u003e \u003cp\u003e22.6 Cancer Cell Migration with Cell–Cell Interaction 569\u003c\/p\u003e \u003cp\u003eReferences 576\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAppendix A Units and Property Data 577\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eA.1 American National Standard for SI Units 577\u003c\/p\u003e \u003cp\u003eA.2 Definitions of Concentration 579\u003c\/p\u003e \u003cp\u003eA.3 Thermodynamic Properties 580\u003c\/p\u003e \u003cp\u003eA.4 Transport Properties 583\u003c\/p\u003e \u003cp\u003eReferences 586\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAppendix B Representing Transport Processes in Complex Systems 587\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eB.1 Vector and Tensor Operations 587\u003c\/p\u003e \u003cp\u003eB.2 Nonequilibrium Thermodynamics 592\u003c\/p\u003e \u003cp\u003eB.3 Spatially Averaged Balances for Heterogeneous Tissue 596\u003c\/p\u003e \u003cp\u003eB.4 Tables for Fluid Motion in Common Coordinate Systems 602\u003c\/p\u003e \u003cp\u003eReferences 604\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAppendix C Mathematical Methods 605\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eC.1 Dimensionless Forms and Scaling 605\u003c\/p\u003e \u003cp\u003eC.2 Inversion of Square Matrices 608\u003c\/p\u003e \u003cp\u003eC.3 Initial-value Problems 609\u003c\/p\u003e \u003cp\u003eC.4 Laplace Transforms 613\u003c\/p\u003e \u003cp\u003eC.5 Alternative Representation of a Point Source 614\u003c\/p\u003e \u003cp\u003eC.6 Similarity Transform of a Partial Differential Equation 615\u003c\/p\u003e \u003cp\u003eNomenclature 619\u003c\/p\u003e \u003cp\u003eIndex 624\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default 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