{"product_id":"biomacromolecules-9780471713975","title":"Biomacromolecules","description":"\u003cb\u003eBook Synopsis\u003c\/b\u003e\u003cbr\u003eThis book is the first to offer an integrated, comprehensive overview of the structure and function of biomacromolecules together with a summary of the latest advances from bioinformatics and functional genomics.\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTrade Review\u003c\/b\u003e\u003cbr\u003e\"[The book] covers, in 18 chapters, most of what one would ever want to know about macromolecules' structure and functions.\" (\u003ci\u003eBiotechnology Journal\u003c\/i\u003e, June 2008)\u003cbr\u003e\u003cbr\u003e\u003cb\u003eTable of Contents\u003c\/b\u003e\u003cbr\u003ePreface.  \u003cp\u003eAbbreviations in Repetitive Use.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 1.\u003c\/b\u003e INTRODUCTION.\u003c\/p\u003e \u003cp\u003e1.1 Prelude.\u003c\/p\u003e \u003cp\u003e1.2 Covalent Bonds.\u003c\/p\u003e \u003cp\u003e1.3 Noncovalent Interactions.\u003c\/p\u003e \u003cp\u003e1.4 Isomerism: Configuration versus Conformation.\u003c\/p\u003e \u003cp\u003e1.5 Trilogy.\u003c\/p\u003e \u003cp\u003e1.6 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 2.\u003c\/b\u003e MONOMER CONSTITUENTS OF BIOMACROMOLECULES.\u003c\/p\u003e \u003cp\u003e2.1 Nucleotides: Constituents of Nucleic Acids.\u003c\/p\u003e \u003cp\u003e2.2 á-Amino Acids: Constituents of Proteins.\u003c\/p\u003e \u003cp\u003e2.3 Monosaccharides: Constituents of Glycans.\u003c\/p\u003e \u003cp\u003e2.4 Addendum.\u003c\/p\u003e \u003cp\u003e2.5 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 3.\u003c\/b\u003e PURIFICATION AND CHARACTERIZATION.\u003c\/p\u003e \u003cp\u003e3.1 Purification: Overview.\u003c\/p\u003e \u003cp\u003e3.2 Purification: Chromatography.\u003c\/p\u003e \u003cp\u003e3.3 Purification: Electrophoresis.\u003c\/p\u003e \u003cp\u003e3.4 Characterization: General.\u003c\/p\u003e \u003cp\u003e3.6 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 4.\u003c\/b\u003e BIOMACROMOLECULAR STRUCTURE: NUCLEIC ACIDS.\u003c\/p\u003e \u003cp\u003e4.1 Structural Organization.\u003c\/p\u003e \u003cp\u003e4.2 Sequence Analysis of Nucleic Acids.\u003c\/p\u003e \u003cp\u003e4.3 Secondary Structure and Structure Polymorphism of DNA.\u003c\/p\u003e \u003cp\u003e4.4 Supercoiling and Tertiary Structure of DNA.\u003c\/p\u003e \u003cp\u003e4.5 Classification and Structures of RNA.\u003c\/p\u003e \u003cp\u003e4.6 RNA Folds and Structure Motifs.\u003c\/p\u003e \u003cp\u003e4.7 Energetics of Nucleic Acid Structure.\u003c\/p\u003e \u003cp\u003e4.8 Nucleic Acid Application.\u003c\/p\u003e \u003cp\u003e4.9 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 5.\u003c\/b\u003e BIOMACROMOLECULAR STRUCTURE: PROTEINS.\u003c\/p\u003e \u003cp\u003e5.1 Architecture of Protein Molecules.\u003c\/p\u003e \u003cp\u003e5.2 Primary Structure of Proteins: Chemical and Enzymatic Sequence Analysis.\u003c\/p\u003e \u003cp\u003e5.3 Primary Structure of Proteins: Sequence Analysis by Tandem Mass Spectrometry.\u003c\/p\u003e \u003cp\u003e5.4 Conformational Map.\u003c\/p\u003e \u003cp\u003e5.5 Secondary Structures and Motifs of Proteins.\u003c\/p\u003e \u003cp\u003e5.6 Domains and Tertiary Structures of Proteins.\u003c\/p\u003e \u003cp\u003e5.7 Classification of Protein Structures.\u003c\/p\u003e \u003cp\u003e5.8 Quaternary (Subunit) Structures of Proteins.\u003c\/p\u003e \u003cp\u003e5.9 Quinternary Structure Exemplified: Nucleoproteins.\u003c\/p\u003e \u003cp\u003e5.10 Conformational Energetics.\u003c\/p\u003e \u003cp\u003e5.11 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 6.\u003c\/b\u003e BIOMACROMOLECULAR STRUCTURE: POLYSACCHARIDES.\u003c\/p\u003e \u003cp\u003e6.1 Propagation of Polysaccharide Chains.\u003c\/p\u003e \u003cp\u003e6.2 Sequence Analysis of Polysaccharides: Primary Structure.\u003c\/p\u003e \u003cp\u003e6.3 Conformation: Secondary and Tertiary Structures of Polysaccharide Chains.\u003c\/p\u003e \u003cp\u003e6.4 Conformation: Description of Some Polysaccharide Structures.\u003c\/p\u003e \u003cp\u003e6.5 Glycobiology: Study of Glycoprotein- Associated Glycans.\u003c\/p\u003e \u003cp\u003e6.6 Neoglycoproteins.\u003c\/p\u003e \u003cp\u003e6.7 Organizational Levels of Biomacromolecular Structures.\u003c\/p\u003e \u003cp\u003e6.8 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 7.\u003c\/b\u003e STUDIES OF BIOMACROMOLECULAR STRUCTURES: SPECTROSCOPIC ANALYSIS OF CONFORMATION.\u003c\/p\u003e \u003cp\u003e7.1 Biochemical Spectroscopy: Overview.\u003c\/p\u003e \u003cp\u003e7.2 Ultraviolet and Visible Absorption Spectroscopy.\u003c\/p\u003e \u003cp\u003e7.3 Fluorescence Spectroscopy.\u003c\/p\u003e \u003cp\u003e7.4 Infrared Spectroscopy.\u003c\/p\u003e \u003cp\u003e7.5 Nuclear Magnetic Resonance Spectroscopy.\u003c\/p\u003e \u003cp\u003e7.6 Optical Rotatory Dispersion and Circular Dichroism Spectroscopy.\u003c\/p\u003e \u003cp\u003e7.7 X-ray Diffraction Spectroscopy.\u003c\/p\u003e \u003cp\u003e7.8 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 8.\u003c\/b\u003e STUDIES OF BIOMACROMOLECULAR STRUCTURES: CHEMICAL SYNTHESIS.\u003c\/p\u003e \u003cp\u003e8.1 Rationale.\u003c\/p\u003e \u003cp\u003e8.2 Synthetic Strategy: Conventional Approach.\u003c\/p\u003e \u003cp\u003e8.3 Synthetic Strategy: Solid Phase Approach.\u003c\/p\u003e \u003cp\u003e8.4 Practice of Solid Phase Synthesis and Its Application.\u003c\/p\u003e \u003cp\u003e8.5 Combinatorial Synthesis.\u003c\/p\u003e \u003cp\u003e8.6 Biochemical Polypeptide Chain Ligation.\u003c\/p\u003e \u003cp\u003e8.7 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 9.\u003c\/b\u003e STUDIES OF BIOMACROMOLECULAR STRUCTURES: COMPUTATION AND MODELING.\u003c\/p\u003e \u003cp\u003e9.1 Potential Energy and Molecular Thermodynamics.\u003c\/p\u003e \u003cp\u003e9.2 Molecular Modeling: Molecular Mechanical Approach.\u003c\/p\u003e \u003cp\u003e9.3 Statistical Thermodynamics.\u003c\/p\u003e \u003cp\u003e9.4 Structural Transition: Examples.\u003c\/p\u003e \u003cp\u003e9.5 Structure Prediction from Sequence by Statistical Methods.\u003c\/p\u003e \u003cp\u003e9.6 Molecular Docking: Prediction of Biomacromolecular Binding.\u003c\/p\u003e \u003cp\u003e9.7 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 10.\u003c\/b\u003e BIOMACROMOLECULAR INTERACTION.\u003c\/p\u003e \u003cp\u003e10.1 Biomacromolecules in Solution.\u003c\/p\u003e \u003cp\u003e10.2 Multiple Equilibria.\u003c\/p\u003e \u003cp\u003e10.3 Allosterism and Cooperativity.\u003c\/p\u003e \u003cp\u003e10.4 Specificity and Diversity of Antibody- Antigen Interactions.\u003c\/p\u003e \u003cp\u003e10.5 Complementarity in Nucleic Acid Interactions.\u003c\/p\u003e \u003cp\u003e10.6 Molecular Recognition in Carbohydrate- Lectin Interaction.\u003c\/p\u003e \u003cp\u003e10.7 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 11.\u003c\/b\u003e BIOMACROMOLECULAR CATALYSIS.\u003c\/p\u003e \u003cp\u003e11.1 Biocatalyst: Definition and Classification.\u003c\/p\u003e \u003cp\u003e11.2 Characteristics of Enzymes.\u003c\/p\u003e \u003cp\u003e11.3 Enzyme Kinetics.\u003c\/p\u003e \u003cp\u003e11.4 Enzyme Mechanisms.\u003c\/p\u003e \u003cp\u003e11.5 Enzyme Regulation.\u003c\/p\u003e \u003cp\u003e11.6 Abzyme.\u003c\/p\u003e \u003cp\u003e11.7 Ribozyme.\u003c\/p\u003e \u003cp\u003e11.8 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 12.\u003c\/b\u003e SIGNAL TRANSDUCTION AND BIODEGRADATION.\u003c\/p\u003e \u003cp\u003e12.1 Chemical Transduction: Metabolism.\u003c\/p\u003e \u003cp\u003e12.2 Elements of Signal Transduction.\u003c\/p\u003e \u003cp\u003e12.3 Effector Enzymes and Signal Transduction.\u003c\/p\u003e \u003cp\u003e12.4 Topics on Signal Transduction.\u003c\/p\u003e \u003cp\u003e12.5 Apoptosis.\u003c\/p\u003e \u003cp\u003e12.6 Hydrolysis versus Phosphorolysis of Glycans.\u003c\/p\u003e \u003cp\u003e12.7 Nucleolysis of Nucleic Acids.\u003c\/p\u003e \u003cp\u003e12.8 Proteolysis and Protein Degradation.\u003c\/p\u003e \u003cp\u003e12.9 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 13.\u003c\/b\u003e BIOSYNTHESIS AND GENETIC TRANSMISSION.\u003c\/p\u003e \u003cp\u003e13.1 Saccharide Biosynthesis and Glycobiology.\u003c\/p\u003e \u003cp\u003e13.2 Genetic Information and Transmission.\u003c\/p\u003e \u003cp\u003e13.3 DNA Replication and Repair.\u003c\/p\u003e \u003cp\u003e13.4 Biosynthesis and Transcription of RNA.\u003c\/p\u003e \u003cp\u003e13.5 Translation and Protein Biosynthesis.\u003c\/p\u003e \u003cp\u003e13.6 Folding of Biomacromolecules.\u003c\/p\u003e \u003cp\u003e13.7 Bioengineering of Biomacromolecules.\u003c\/p\u003e \u003cp\u003e13.8 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 14.\u003c\/b\u003e BIOMACROMOLECULAR INFORMATICS.\u003c\/p\u003e \u003cp\u003e14.1 Overview.\u003c\/p\u003e \u003cp\u003e14.2 Biosequences.\u003c\/p\u003e \u003cp\u003e14.3 Microarray: General Description.\u003c\/p\u003e \u003cp\u003e14.4 Computer Technology.\u003c\/p\u003e \u003cp\u003e14.5 Informatics.\u003c\/p\u003e \u003cp\u003e14.6 Gene Ontology.\u003c\/p\u003e \u003cp\u003e14.7 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 15.\u003c\/b\u003e GENOMICS.\u003c\/p\u003e \u003cp\u003e15.1 Genome: Features and Organization.\u003c\/p\u003e \u003cp\u003e15.2 Genome Informatics: Databases and Web Servers.\u003c\/p\u003e \u003cp\u003e15.3 Approaches to Gene Identification.\u003c\/p\u003e \u003cp\u003e15.4 Gene Expression.\u003c\/p\u003e \u003cp\u003e15.5 Genome Project.\u003c\/p\u003e \u003cp\u003e15.6 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 16.\u003c\/b\u003e PROTEOMICS.\u003c\/p\u003e \u003cp\u003e16.1 Proteome: Features and Properties.\u003c\/p\u003e \u003cp\u003e16.2 Proteome Informatics: Sequence Databases and Servers.\u003c\/p\u003e \u003cp\u003e16.3 Proteome Informatics: Structure Databases and Servers.\u003c\/p\u003e \u003cp\u003e16.4 Proteome Informatics: Proteomic Servers.\u003c\/p\u003e \u003cp\u003e16.5 Protein Structure Analysis Using Bioinformatics.\u003c\/p\u003e \u003cp\u003e16.6 Investigation of Proteome Expression and Function.\u003c\/p\u003e \u003cp\u003e16.7 Metabolome.\u003c\/p\u003e \u003cp\u003e16.8 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 17.\u003c\/b\u003e GLYCOMICS.\u003c\/p\u003e \u003cp\u003e17.1 Features of Glycomics.\u003c\/p\u003e \u003cp\u003e17.2 Glycomic Databases and Servers.\u003c\/p\u003e \u003cp\u003e17.3 Glycomics: Genetic Approaches.\u003c\/p\u003e \u003cp\u003e17.4 Glycomics: Proteoglycomic Approaches.\u003c\/p\u003e \u003cp\u003e17.5 Glycomics: Chemoglycomic Approaches.\u003c\/p\u003e \u003cp\u003e17.6 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eCHAPTER 18.\u003c\/b\u003e BIOMACROMOLECULAR EVOLUTION.\u003c\/p\u003e \u003cp\u003e18.1 Variation in Biomacromolecular Sequences.\u003c\/p\u003e \u003cp\u003e18.2 Element of Molecular Phylogeny.\u003c\/p\u003e \u003cp\u003e18.3 Phylogenetic Analysis of Biosequences.\u003c\/p\u003e \u003cp\u003e18.4 Application of Sequence Analyses in Phylogenetic Inference.\u003c\/p\u003e \u003cp\u003e18.5 Evolution of Biosequences.\u003c\/p\u003e \u003cp\u003e18.6 Evolution of Protein Structure and Function.\u003c\/p\u003e \u003cp\u003e18.7 References.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eINDEX.\u003c\/b\u003e\u003c\/p\u003e","brand":"John Wiley \u0026 Sons Inc","offers":[{"title":"Default Title","offer_id":49525407777111,"sku":"9780471713975","price":160.5,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0817\/1739\/5799\/files\/9780471713975.jpg?v=1731860400","url":"https:\/\/bookcurl.com\/products\/biomacromolecules-9780471713975","provider":"Book Curl","version":"1.0","type":"link"}